Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Mohamad Samer Mouksassi"'
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 10, Pp 1283-1293 (2022)
Abstract The current tutorial describes why forest plots are needed for an effective communication of covariates effects, how they are constructed, and how they should be presented. Simulation‐based methodologies allowing the user to evaluate the m
Externí odkaz:
https://doaj.org/article/c83b89f55cf64660b1be3521588802b9
Autor:
Ronald D. Perrone, Mohamad-Samer Mouksassi, Klaus Romero, Frank S. Czerwiec, Arlene B. Chapman, Berenice Y. Gitomer, Vicente E. Torres, Dana C. Miskulin, Steve Broadbent, Jean F. Marier
Publikováno v:
Kidney International Reports, Vol 2, Iss 3, Pp 451-460 (2017)
Total kidney volume (TKV) is a promising imaging biomarker for tracking and predicting the natural history of patients with autosomal dominant polycystic kidney disease. Methods: A drug development tool was developed by linking longitudinal TKV measu
Externí odkaz:
https://doaj.org/article/f08a175e4d28433fa812dcc450b0272e
Autor:
Ronald D. Perrone, Mohamad-Samer Mouksassi, Klaus Romero, Frank S. Czerwiec, Arlene B. Chapman, Berenice Y. Gitomer, Vicente E. Torres, Dana C. Miskulin, Steve Broadbent, Jean F. Marier
Publikováno v:
Kidney International Reports, Vol 2, Iss 3, Pp 442-450 (2017)
Autosomal dominant polycystic kidney disease is the most common hereditary kidney disease. TKV is a promising imaging biomarker for tracking and predicting the natural history of autosomal dominant polycystic kidney disease. The prognostic value of T
Externí odkaz:
https://doaj.org/article/a822dc0a1d63446397c72464395de61a
Autor:
Lazaro M. Mwandigha, Keith J. Fraser, Azra C. Ghani, Mohamad-Samer Mouksassi, Amy Racine-Poon
Publikováno v:
International Journal of Epidemiology
Background Cluster randomized trials (CRTs) are increasingly used to study the efficacy of interventions targeted at the population level. Formulae exist to calculate sample sizes for CRTs, but they assume that the domain of the outcomes being consid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3bddd77b15631d7247593b00089b17
http://hdl.handle.net/10044/1/100446
http://hdl.handle.net/10044/1/100446
Publikováno v:
Pain physician. 21(4)
Understanding analgesic pharmacodynamics (PD) in the elderly is key to optimising pain management. Electrically stimulated pain models (ESPM) permit assessment of pain responses in humans. C and A-delta sensory fibres convey pain and respond to low f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db6d9761d6dde698f1d1cad980fc002e
https://pubmed.ncbi.nlm.nih.gov/30045593
https://pubmed.ncbi.nlm.nih.gov/30045593
Autor:
Sybil Skinner-Robertson, Caroline Fradette, Sylvie Bouchard, Mohamad-Samer Mouksassi, France Varin
Publikováno v:
Drugs & Aging. 32:1029-1043
Tramadol is frequently used in geriatric patients; however, pharmacokinetic (PK) publications on tramadol and O-desmethyltramadol (ODM) in elderly patients are rare. Our objective was to characterize the PK of tramadol and ODM, including absorption p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d65c9a91cf9c6a6b2484eb9fac80b3e
https://doi.org/10.1007/s40266-015-0315-4
https://doi.org/10.1007/s40266-015-0315-4
Publikováno v:
Clinical Pharmacology in Drug Development. 4:463-472
Motesanib is a small molecule and potent multikinase inhibitor with antiangiogenic and antitumor activity. Population pharmacokinetic (POPPK) modeling of motesanib and M4, an active metabolite, was performed to assess sources of variability in cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8434d670fc423026db35ee72a0bcdb58
https://doi.org/10.1002/cpdd.196
https://doi.org/10.1002/cpdd.196
Autor:
Mohamad Samer Mouksassi, Berenice Gitomer, Vicente E. Torres, Arlene B. Chapman, Dana C. Miskulin, Ronald D. Perrone, Frank S. Czerwiec, Jean F. Marier, Steve Broadbent, Klaus Romero
Publikováno v:
Kidney International Reports, Vol 2, Iss 3, Pp 451-460 (2017)
Kidney International Reports
Kidney International Reports
Introduction Total kidney volume (TKV) is a promising imaging biomarker for tracking and predicting the natural history of patients with autosomal dominant polycystic kidney disease. Methods A drug development tool was developed by linking longitudin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6adec8d864eb57ab79f9587cb13500f6
Publikováno v:
Clinical Pharmacology in Drug Development. 4:210-217
Thrombomodulin alfa is a soluble recombinant human thrombomodulin that was reported to enhance the reversal of disseminated intravascular coagulation (DIC) in subjects with sepsis or hematologic malignancy and reduce mortality in subjects with sepsis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a4c3dad3bc678c919496e4af481cbb7
https://doi.org/10.1002/cpdd.163
https://doi.org/10.1002/cpdd.163
Publikováno v:
Journal of Clinical Pharmacology
Ceftolozane/tazobactam is a novel antipseudomonal cephalosporin and β-lactamase inhibitor in clinical development for treatment of complicated urinary tract (cUTI) and intra-abdominal (cIAI) infections and nosocomial pneumonia. The population pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702766eb35b8891257441b273b6a896c
https://doi.org/10.1002/jcph.395
https://doi.org/10.1002/jcph.395