Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Mohamad Reza, Ganjalikhany"'
Publikováno v:
Heliyon, Vol 10, Iss 23, Pp e40563- (2024)
Cancer is known as the main cause of mortality in the world, and every year, the rate of incidence and death due to cancer is increasing. Bioactive peptides are one of the novel therapeutic options that are considered a suitable alternative to toxic
Externí odkaz:
https://doaj.org/article/84d9757ba87a4ecf8f73e08a4550d4a0
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0304270 (2024)
Cancer control and treatment remain a significant challenge in cancer therapy and recently immune checkpoints has considered as a novel treatment strategy to develop anti-cancer drugs. Many cancer types use the immune checkpoints and its ligand, PD-1
Externí odkaz:
https://doaj.org/article/76e6fe4e8c5c4e1aa846a7e44b2bfd21
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract In recent years, the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as the cause of the coronavirus disease (COVID-19) global pandemic, and its variants, especially those with higher transmissibility and substanti
Externí odkaz:
https://doaj.org/article/ad88c478be2a4f4094f42dcbca6cffdc
Autor:
Farzaneh Jafary, Farzane Abasi Joozdani, Kiana Shahzamani, Sepideh Jafari, Hossein Mirhendi, Mohamad Reza Ganjalikhany
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291210 (2023)
During replication, some mutations occur in SARS-CoV-2, the causal agent of COVID-19, leading to the emergence of different variants of the virus. The mutations that accrue in different variants of the virus, influence the virus' ability to bind to h
Externí odkaz:
https://doaj.org/article/0e207fefc99e441fa5115c3bf2af42d1
Autor:
Parnian Navabi, Mohamad Reza Ganjalikhany, Sepideh Jafari, Moein Dehbashi, Mazdak Ganjalikhani-Hakemi
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 24, Iss 3, Pp 360-368 (2021)
Objective(s): IL-2Rα plays a critical role in maintaining immune function. However, expression and secretion of CD25 in various malignant disorders and autoimmune diseases are now well established. Thus, CD25 is considered an important target candid
Externí odkaz:
https://doaj.org/article/b52bda3be7254dae8a7f66eb516382e5
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a newly-discovered coronavirus and responsible for the spread of coronavirus disease 2019 (COVID-19). SARS-CoV-2 infected millions of people in the world and immediately became
Externí odkaz:
https://doaj.org/article/2fb603d2d14949b984570c78da92d5f7
Autor:
Hossein Mohammadian, Karim Mahnam, Hamid Mirmohammad Sadeghi, Mohamad Reza Ganjalikhany, Vajihe Akbari
Publikováno v:
Research in Pharmaceutical Sciences, Vol 15, Iss 2, Pp 164-173 (2020)
Background and purpose: Tobacco etch virus (TEV) protease is a protease with high sequence specificity which is useful for the cleavage of fusion proteins. A major limitation of this enzyme is its relatively poor solubility. This study aimed to inves
Externí odkaz:
https://doaj.org/article/6fde3842b55e4fa1a737b17517aa6aef
Autor:
Moein Dehbashi, Zohreh Hojati, Majid Motovali-bashi, Mohamad Reza Ganjalikhany, William C. Cho, Akihiro Shimosaka, Parnian Navabi, Mazdak Ganjalikhani-Hakemi
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
For many years, high-affinity subunit of IL-2 receptor (CD25) has been considered as a promising therapeutic target for different pathologic conditions like allograft rejection, autoimmunity, and cancers. Although CD25 is transiently expressed by new
Externí odkaz:
https://doaj.org/article/b5e5271a349a4bbbb5dee82473356eba
Autor:
Hooria Seyedhosseini Ghaheh, Mohamad Reza Ganjalikhany, Parichehreh Yaghmaei, Morteza Pourfarzam, Hamid Mir Mohammad Sadeghi
Publikováno v:
Research in Pharmaceutical Sciences, Vol 14, Iss 4, Pp 359-368 (2019)
Reteplase (recombinant plasminogen activator, r-PA) is a thrombolytic agent recombined from tissue-type plasminogen activator (t-PA), which has several prominent features such as strong thrombolytic ability and E. coli expressibility. Despite these o
Externí odkaz:
https://doaj.org/article/7a62a8ed486941d5ad113c6eb85c555c
Autor:
Maryam Bidram, Yue Zhao, Natalia G. Shebardina, Alexey V. Baldin, Alexandr V. Bazhin, Mohamad Reza Ganjalikhany, Andrey A. Zamyatnin, Mazdak Ganjalikhani-hakemi
Publikováno v:
Vaccines, Vol 9, Iss 10, p 1060 (2021)
Malignant melanoma is one of the most aggressive forms of cancer and the leading cause of death from skin tumors. Given the increased incidence of melanoma diagnoses in recent years, it is essential to develop effective treatments to control this dis
Externí odkaz:
https://doaj.org/article/fee0951c76bf441bb6e7f03695567e1f