132 HLA-independent T cell receptors effectively target low abundance antigens

Autor: Zeguo Zhao, Mohamad Hamieh, Justin Eyquem, Michel Sadelain, Maria Sjöstrand, Jorge Mansilla-Soto, Sascha Haubner, Judith Feucht, Noémie Paillon, Andres Zucchetti, Zhuoning Li, Pieter Lindenbergh, Michelle Saetersmoen, Mathieu Maurin, Archana Iyer, Anton Dobrin, Andreina Garcia Angus, Matthew Miele, Theodoros Giavridis, Sjoukje van der Stegen, Fella Tamzalit, Morgan Huse, Ronald Hendrickson, Claire Hivroz

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)

Externí odkaz: https://doaj.org/article/595628448f684db780a076008ffd5232

Brucella prosthetic valve endocarditis with septic and cardiogenic shock

Autor: Amal Hamieh, Mohamad Hamieh

Publikováno v: IDCases, Vol 21, Iss , Pp e00881- (2020)

A young man with aortic prosthetic valve replacement, presented with prolonged fever and diagnosed with brucella endocarditis based on positive transthoracic echo findings with high titer positive brucellacapt serology. He was started on medical trea

Externí odkaz: https://doaj.org/article/36ed1c86170b4ff5bc12a8f5c7c55490

Correction: Exonic Splicing Mutations Are More Prevalent than Currently Estimated and Can Be Predicted by Using In Silico Tools.

Autor: Omar Soukarieh, Pascaline Gaildrat, Mohamad Hamieh, Aurélie Drouet, Stéphanie Baert-Desurmont, Thierry Frébourg, Mario Tosi, Alexandra Martins

Publikováno v: PLoS Genetics, Vol 12, Iss 4, p e1005971 (2016)

Externí odkaz: https://doaj.org/article/f8225fa7a21643beb504a37a145a5344

Study of genetic mutations and dynamic spread of SARS-CoV-2 pandemic and prediction of its evolution according to the SIR model

Autor: Mohamad, Hamieh, Mary, Doumit, Joumana, Toufaily, Tayssir, Hamieh

In this work, we aim to study that the dynamics behavior for cumulative number of SARS-CoV-2 pandemic can provide information on the overall behavior of the spread over daily time.The cumulative data can be synthesized in an empirical form obtained f

Externí odkaz: http://arxiv.org/abs/2011.06694

Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells

Autor: Sjoukje J. C. van der Stegen, Pieter L. Lindenbergh, Roseanna M. Petrovic, Hongyao Xie, Mame P. Diop, Vera Alexeeva, Yuzhe Shi, Jorge Mansilla-Soto, Mohamad Hamieh, Justin Eyquem, Annalisa Cabriolu, Xiuyan Wang, Ramzey Abujarour, Tom Lee, Raedun Clarke, Bahram Valamehr, Maria Themeli, Isabelle Riviere, Michel Sadelain

Publikováno v: van der Stegen, S J C, Lindenbergh, P L, Petrovic, R M, Xie, H, Diop, M P, Alexeeva, V, Shi, Y, Mansilla-Soto, J, Hamieh, M, Eyquem, J, Cabriolu, A, Wang, X, Abujarour, R, Lee, T, Clarke, R, Valamehr, B, Themeli, M, Riviere, I & Sadelain, M 2022, ' Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells ', Nature Biomedical Engineering, vol. 6, no. 11, pp. 1284-1297 . https://doi.org/10.1038/s41551-022-00915-0
Nature Biomedical Engineering, 6(11), 1284-1297. Nature Publishing Group
Nat Biomed Eng

The production of autologous T cells expressing a chimaeric antigen receptor (CAR) is time-consuming, costly and occasionally unsuccessful. T-cell-derived induced pluripotent stem cells (TiPS) are a promising source for the generation of ‘off-the-s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b154e71865ba41f6af9d0b1d675890f
https://doi.org/10.1038/s41551-022-00915-0