Enhancement of oral moxidectin bioavailability in rabbits by lipid co-administration

Autor: Mohamad Firas Bassissi, Michel Alvinerie, Anne Lespine

Publikováno v: Parasitology Research
Parasitology Research, Springer Verlag (Germany), 2004, 94 (3), pp.188-192. ⟨10.1007/s00436-004-1192-7⟩

Moxidectin is a member of the macrocyclic lactone family of drugs widely used for the control of internal and external parasites. Because moxidectin is highly lipophilic, we suspect that lymphatic transport influences the intestinal absorption of ora

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e39a232f0ba0c32c639db44f588778
https://doi.org/10.1007/s00436-004-1192-7

Macrocyclic lactones: distribution in plasma lipoproteins of several animal species including humans

Autor: Michel Alvinerie, Mohamad Firas Bassissi, Anne Lespine

Publikováno v: Comparative Biochemistry and Physiology-Part C: Toxicology and Pharmacology
Comparative Biochemistry and Physiology-Part C: Toxicology and Pharmacology, Elsevier, 2004, 138 (4), pp.437-444. ⟨10.1016/j.cca.2004.07.011⟩

We studied the in vitro distribution of macrocyclic lactones (MLs), lipophilic anthelmintic drugs, in the plasma of several animal species including humans. First, in vitro spiking of goat plasma was performed with ivermectin, moxidectin, abamectin,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1765f6b63492189bff648f9f4debc9
https://hal.inrae.fr/hal-02680351