Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Mohamad Assi"'
Autor:
Marie-Albane Minati, Mohamad Assi, Maxime Libert, Sabine Cordi, Frédéric Lemaigre, Patrick Jacquemin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
KRAS mutants are common in many cancers and wild-type KRAS is essential in development as its absence causes embryonic lethality. Despite this critical role in development and disease, the normal expression pattern of KRAS protein is still largely un
Externí odkaz:
https://doaj.org/article/45865a32c689411d80104951814aaa70
Publikováno v:
Redox Biology, Vol 35, Iss , Pp 101439- (2020)
In this paper of the special issue dedicated for the Olympics 2020, we put the light on an exciting facet of exercise-oncology, which may still be unknown to some audience. Accumulating convincing evidences show that exercise reduces cancer progressi
Externí odkaz:
https://doaj.org/article/7908a4479c6d4696a611b299ebe3e5b2
Publikováno v:
Antioxidants, Vol 10, Iss 7, p 1107 (2021)
Pancreatitis, an inflammation of the pancreas, appears to be a main driver of pancreatic cancer when combined with Kras mutations. In this context, the exact redox mechanisms are not clearly elucidated. Herein, we treated mice expressing a KrasG12D m
Externí odkaz:
https://doaj.org/article/a8db77ce74b4438aaec7b75207a33c8f
Publikováno v:
Antioxidants, Vol 10, Iss 4, p 570 (2021)
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with few therapeutic options. The identification of new promising targets is, therefore, an urgent need. Using available transcriptomic datasets, we first found that Peroxiredoxin-1 gen
Externí odkaz:
https://doaj.org/article/a1605226a5d641dbbe591502a37dd8ce
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6361 (2020)
KRAS is a powerful oncogene responsible for the development of many cancers. Despite the great progress in understanding its function during the last decade, the study of KRAS expression, subcellular localization, and post-translational modifications
Externí odkaz:
https://doaj.org/article/62b541cf12f24443b5769462a1a25355
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
The isolation of ribonucleic acid (RNA) suitable for gene expression studies is challenging in the pancreas, due to its high ribonuclease activity. This is even more complicated during pancreatitis, a condition associated with inflammation and fibros
Externí odkaz:
https://doaj.org/article/be47179060c54c10b39fea10f4145e29
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Lower-extremities sarcoma patients, with bone tumor and soft-tissue sarcoma, are a unique population at high risk of physical dysfunction and chronic heart diseases. Thus, providing an adequate physical activity (PA) program constitutes a primary par
Externí odkaz:
https://doaj.org/article/83256d0f82a34e618ed320f05ecf7a11
Autor:
Mohamad Assi, Alec C. Kimmelman
Publikováno v:
Nature Cancer. 4:596-607
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e8345c782d4d8380218ee465b9fbdf5
https://doi.org/10.1038/s43018-023-00546-7
https://doi.org/10.1038/s43018-023-00546-7
Autor:
Patrick Jacquemin, Frédéric P. Lemaigre, Mariano Barbacid, Luc Bouwens, Carmen Guerra, Jean S. Fain, Maxime Libert, Jonathan Baldan, Hajar Dahou, Nicolas Dauguet, Axelle Loriot, Younes Achouri, Mohamad Assi
Document describing important findings related to the main manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7365ea47b69027aa0851951d5bd97b51
https://doi.org/10.1158/0008-5472.22426914
https://doi.org/10.1158/0008-5472.22426914
Autor:
Patrick Jacquemin, Frédéric P. Lemaigre, Mariano Barbacid, Luc Bouwens, Carmen Guerra, Jean S. Fain, Maxime Libert, Jonathan Baldan, Hajar Dahou, Nicolas Dauguet, Axelle Loriot, Younes Achouri, Mohamad Assi
Document describing important mouse lines, treatment protocols, antibodies and primers used in the present study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa7f094f4b7e772e21332935d3ccddc
https://doi.org/10.1158/0008-5472.22426911.v1
https://doi.org/10.1158/0008-5472.22426911.v1