Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mohak, Sharda"'
Publikováno v:
PLoS Biology, Vol 22, Iss 3, p e3002540 (2024)
DNA methylation plays central roles in diverse cellular processes, ranging from error-correction during replication to regulation of bacterial defense mechanisms. Nevertheless, certain aberrant methylation modifications can have lethal consequences.
Externí odkaz:
https://doaj.org/article/647ee7a5b65142d483987dafdbb71223
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Illumina sequencing platform requires base diversity in the initial 11 cycles for efficient cluster identification and colour matrix estimation. This limitation yields low-quality data for amplicon libraries having homogeneous bas
Externí odkaz:
https://doaj.org/article/c3f24f5605284fc29b23c8066c0f2bd5
Autor:
Raefa Abou Khouzam, Mohak Sharda, Shyama Prasad Rao, Stephanie Maame Kyerewah-Kersi, Nagwa Ahmed Zeinelabdin, Ayda Shah Mahmood, Husam Nawafleh, Munazza Samar Khan, Goutham Hassan Venkatesh, Salem Chouaib
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Hypoxia afflicts the microenvironment of solid tumors fueling malignancy. We investigated the impact of long hypoxia exposure on transcriptional remodeling, tumor mutational burden (TMB), and genomic instability of cancer cells that were grouped base
Externí odkaz:
https://doaj.org/article/6fed90ce929d4c819d8d8363db37fa79
Autor:
Rania Faouzi Zaarour, Mohak Sharda, Bilal Azakir, Goutham Hassan Venkatesh, Raefa Abou Khouzam, Ayesha Rifath, Zohra Nausheen Nizami, Fatima Abdullah, Fatin Mohammad, Hajar Karaali, Husam Nawafleh, Yehya Elsayed, Salem Chouaib
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6848 (2022)
The role of autophagy in lung cancer cells exposed to waterpipe smoke (WPS) is not known. Because of the important role of autophagy in tumor resistance and progression, we investigated its relationship with WP smoking. We first showed that WPS activ
Externí odkaz:
https://doaj.org/article/7e6d5769e16d463a8f459049ee66d495
Publikováno v:
Genome Biology and Evolution
DNA double-strand breaks (DSBs) are a threat to genome stability. In all domains of life, DSBs are faithfully fixed via homologous recombination. Recombination requires the presence of an uncut copy of duplex DNA which is used as a template for repai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8576af30fe853ce9ddf087756f667368
https://doi.org/10.1093/gbe/evaa223
https://doi.org/10.1093/gbe/evaa223
Autor:
Rania F. Zaarour, Mohak Sharda, Bilal Azakir, Goutham Hassan Venkatesh, Raefa Abou Khouzam, Ayesha Rifath, Zohra Nizami, Fatima Abdullah, Fatin Mohammad, Husam Nawafleh, Yehia ElSayed, Salem Chouaib
Publikováno v:
Cancer Research. 82:2995-2995
Smoking is the number one risk factor for lung cancer and tobacco smokers are at 20 to 40 times higher risk of developing lung cancer in comparison to non-smokers. We have previously shown that exposing lung cancer cell lines to tobacco smoke condens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74636fc74e624f82b35bc43e6e675985
https://doi.org/10.1158/1538-7445.am2022-2995
https://doi.org/10.1158/1538-7445.am2022-2995
Autor:
Raefa Abou Khouzam, Nagwa Ahmed Zeinelabdin, Mohak Sharda, Husam Nawafleh, Ayda shah Mahmood, Munazza Samar Khan, Goutham Hassan Venkatesh, Salem Chouaib, Shyama Prasad Rao
Publikováno v:
Cancer Research. 82:5679-5679
Hypoxia afflicts the microenvironment of solid tumors fueling tumor malignancy. Using an 8-gene in vitro hypoxia signature, we have recently shown that pancreatic cancer patients with highly hypoxic tumors experience worse survival and exhibit marker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0311296bf5b331a6ac9989bce21c0a2
https://doi.org/10.1158/1538-7445.am2022-5679
https://doi.org/10.1158/1538-7445.am2022-5679
Autor:
Shyam Sunder, Rangu, Ashish, Beck, Mohak, Sharda, Rita, Mukhopadhyaya, Aswin Sai Narain, Seshasayee, Devashish, Rath
Publikováno v:
Microbiology Resource Announcements
Sphingobium sp. strain RSMS was described earlier as an efficient degrader of tributyl phosphate, an organic pollutant. This report describes the generation and annotation of the genome sequence of Sphingobium sp. strain RSMS, which will facilitate f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91701ba786408b0a38c658b4f12bd78f
https://pubmed.ncbi.nlm.nih.gov/33060264
https://pubmed.ncbi.nlm.nih.gov/33060264
Autor:
Mohak Sharda, Shyam Sunder Rangu, Ashish Beck, Rita Mukhopadhyaya, Aswin Sai Narain Seshasayee, Devashish Rath
Publikováno v:
Microbiology Resource Announcements. 9
Sphingobium sp. strain RSMS was described earlier as an efficient degrader of tributyl phosphate, an organic pollutant. This report describes the generation and annotation of the genome sequence of Sphingobium sp. strain RSMS, which will facilitate f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c002f87c4a37b09317274d2b05d7ec4c
https://doi.org/10.1128/mra.00600-20
https://doi.org/10.1128/mra.00600-20
The current global pandemic COVID-19, caused by SARS-CoV-2, has resulted in millions of infections worldwide in a few months. Global efforts to tackle this situation have produced a tremendous body of genomic data, which can be used for tracing trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cac8001249d3a2d75abbaa49d9d56fe
https://doi.org/10.1101/2020.06.09.082834
https://doi.org/10.1101/2020.06.09.082834
