Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Moh Moh Lian"'
Autor:
Wei Xiong, R. Stott, James F. Markmann, Kang Mi Lee, Moh Moh Lian, Heidi Yeh, Gaoping Zhao, Elsie Akrawi, James I. Kim, Lindsey Fitzgerald, J. Soohoo, Ji Lei, S. Shi, Shaoping Deng
Publikováno v:
European Journal of Immunology. 44:1728-1736
Regulatory B (Breg) cells have been shown to play a critical role in immune homeostasis and in autoimmunity models. We have recently demonstrated that combined anti-T cell immunoglobulin domain and mucin domain-1 and anti-CD45RB antibody treatment re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e60123d90b903fca30245def5e78c4f8
https://doi.org/10.1002/eji.201344062
https://doi.org/10.1002/eji.201344062
Autor:
Daniel J. Moore, James F. Markmann, Heidi Yeh, Major K. Lee, Patrick E. Duff, Samsher Sonawane, James I. Kim, Andrew J. Caton, Moh Moh Lian, Seoung-Hoon Lee, Matthew R O’Connor, Yongwon Choi, Shaoping Deng
Publikováno v:
European Journal of Immunology. 40:1369-1374
Involvement of Treg in transplant tolerance has been demonstrated in multiple models. During the active process of graft rejection, these regulatory cells are themselves regulated and inactivated, a process termed counter-regulation. We hypothesize t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c466b7610918242c47131d9d3af794c9
https://doi.org/10.1002/eji.200940046
https://doi.org/10.1002/eji.200940046
Autor:
Heidi Yeh, Mohammad Mohiuddin, Shaoping Deng, Jing Wang, Moh Moh Lian, James F. Markmann, Xiaolun Huang, Samsher Sonawane, Yi Gu, James I. Kim, Daniel J. Moore
Publikováno v:
Transplantation. 85:675-680
The success of transplantation for numerous life-threatening illnesses is currently predicated on the efficacy of immunosuppressive therapies. Given the toxicities of these regimens, there is a strong impetus to develop new strategies that induce per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f14b93ef629c24e27bbaddbee75a061
https://doi.org/10.1097/tp.0b013e3181663422
https://doi.org/10.1097/tp.0b013e3181663422
Autor:
Steven E. Raper, Victor M. Rivera, Moh Moh Lian, Franz M. Matschinsky, Marko Z. Vatamaniuk, Tim Clackson, James M. Wilson, Jean-Pierre Louboutin, Shaoping Deng, Gary P. Kobinger, James F. Markmann
Publikováno v:
Molecular Therapy. 11(1):105-111
Transplantation of allogeneic islets can correct the metabolic abnormalities of Type I diabetes. Limited availability of donor pancreas tissues restricts the application of this therapeutic modality to a subset of eligible recipients. In an attempt t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818eccb44b8cf02eccaaf4d41fea9b36
Autor:
Brigitte Koeberlein, James F. Markmann, Ergun Velidedeoglu, Nicolai M. Doliba, Xiaolun Huang, Franz M. Matschinsky, Moh Moh Lian, Adam M. Frank, Marko Z. Vatamaniuk, Ali Naji, Niraj M. Desai, Clyde F. Barker, Bryan A. Wolf, Shaoping Deng
Publikováno v:
Diabetes. 53:624-632
Type 2 diabetic subjects manifest both disordered insulin action and abnormalities in their pancreatic islet cells. Whether the latter represents a primary defect or is a consequence of the former is unknown. To examine the β-cell mass and function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4b937333275442e1cdffa3075098b9
https://doi.org/10.2337/diabetes.53.3.624
https://doi.org/10.2337/diabetes.53.3.624
Autor:
Nicolai M. Doliba, Ewan Bell, Xiaolun Huang, Adam M. Frank, Kenneth L. Brayman, James F. Markmann, Ergun Velidedeoglu, Eileen Markmann, Ali Naji, Niraj M. Desai, Chengyang Liu, Bryan A. Wolf, Franz M. Matschinsky, Shaoping Deng, Clyde F. Barker, Moh Moh Lian, Marko Vitamaniuk
Publikováno v:
Transplantation. 75:1423-1429
Recent improvements in isolated islet transplantation indicate that this therapy may ultimately prove applicable to patients with type I diabetes. An obstacle preventing widespread application of islet transplantation is an insufficient supply of cad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5de1c6cca97b31e6f70e0c18b3cec8c
https://doi.org/10.1097/01.tp.0000061119.32575.f4
https://doi.org/10.1097/01.tp.0000061119.32575.f4
Vulnerability of allografts to rejection by MHC class II-restricted T-cell receptor transgenic mice1
Autor:
Ergun Velidedeoglu, Daniel J. Moore, Andrew L. Singer, Moh Moh Lian, Niraj M. Desai, Joseph W. Markmann, Beth P. Jarrett, Xiaolun Huang, Major K. Lee, and James F. Markmann, Andrew J. Caton, Adam M. Frank, Shaoping Deng
Publikováno v:
Transplantation. 75:1415-1422
Background Examination of the in vivo activation and function of CD4+ T cells in response to allografts may advance our understanding of the rejection process. We analyzed the capacity of transgenic class II-restricted CD4 T cells to reject skin, car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf484bdd324887b628f3951c46e3e302
https://doi.org/10.1097/01.tp.0000064296.65628.6c
https://doi.org/10.1097/01.tp.0000064296.65628.6c
Autor:
Shaoping Deng, Marko Z. Vatamaniuk, Nicolai M. Doliba, Steven E. Raper, Ewan Bell, Bryan A. Wolf, James F. Markmann, Moh Moh Lian, Franz M. Matschinsky, J. Wang
Publikováno v:
Diabetologia. 46:386-393
Recent success in islet transplantation renews the hope for the complete cure of patients afflicted with Type 1 diabetes. However, in the Edmonton series, two to four pancreas donors were required to obtain a sufficient islet mass to reverse the diab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5e9245a2d0f85a6966dfc91873b7e8
https://doi.org/10.1007/s00125-003-1038-3
https://doi.org/10.1007/s00125-003-1038-3
Suppressive regulatory T cell activity is potentiated by glycogen synthase kinase 3{beta} inhibition
Autor:
Robert B. Colvin, Stephanie de Haseth, Joren C. Madsen, Jay A. Graham, A. Benedict Cosimi, Alessandro Alessandrini, Michael Fray, Kang Mi Lee, Moh Moh Lian, Shaoping Deng, James Kim, Gilles Benichou, Catharine M. Chase, James F. Markmann
Publikováno v:
The Journal of biological chemistry. 285(43)
The mechanism by which regulatory T (Treg) cells suppress the immune response is not well defined. A recent study has shown that β-catenin prolongs Treg cell survival. Because β-catenin is regulated by glycogen synthase kinase 3β (GSK-3β)-directe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa9c0462a58f730e82949cf20f955d5
https://pubmed.ncbi.nlm.nih.gov/20729209
https://pubmed.ncbi.nlm.nih.gov/20729209
Autor:
Patrick E. Duff, Yongwon Choi, Daniel J. Moore, Seoung-Hoon Lee, James I. Kim, Shaoping Deng, Major K. Lee, Andrew J. Caton, James F. Markmann, Samsher Sonawane, Moh Moh Lian, Heidi Yeh
Publikováno v:
Transplantation. 88(10)
Background Many models of transplant tolerance have been found to depend on the induction of regulatory T cells (Tregs). Innate immune signals are known to suppress Tregs thereby augmenting immunity by abrogating Treg function. Such signals may also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102840578c55ae19f0f869ecd87b1e38
https://pubmed.ncbi.nlm.nih.gov/19935368
https://pubmed.ncbi.nlm.nih.gov/19935368