Zobrazeno 1 - 10
of 335
pro vyhledávání: '"Mogens H Jensen"'
Autor:
Thomas Holst-Hansen, Pernille Yde Nielsen, Mogens H. Jensen, Thomas Mandrup-Poulsen, Ala Trusina
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Type 2 diabetes (T2D) is associated with a systemic increase in the pro-inflammatory cytokine IL-1β. While transient exposure to low IL-1β concentrations improves insulin secretion and β-cell proliferation in pancreatic islets, prolonged
Externí odkaz:
https://doaj.org/article/a2ec5519be3141949357ae26ecb70924
Autor:
Malthe S Nordentoft, Naoya Takahashi, Mathias S Heltberg, Mogens H Jensen, Rune N Rasmussen, Athanasia Papoutsi
Publikováno v:
PLoS Biology, Vol 22, Iss 12, p e3002935 (2024)
During neuronal activity, the extracellular concentration of potassium ions ([K+]o) increases substantially above resting levels, yet it remains unclear what role these [K+]o changes play in the dendritic integration of synaptic inputs. We here used
Externí odkaz:
https://doaj.org/article/c60d0dbb7b614c4199f26a5b6595b80d
Autor:
Christian Michelsen, Christoffer C. Jørgensen, Mathias Heltberg, Mogens H. Jensen, Alessandra Lucchetti, Pelle B. Petersen, Troels Petersen, Henrik Kehlet, The Center for Fast-track Hip Knee Replacement Collaborative group, Frank Madsen, Torben B. Hansen, Kirill Gromov, Thomas Jakobsen, Claus Varnum, Soren Overgaard, Mikkel Rathsach, Lars Hansen
Publikováno v:
BMC Anesthesiology, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Machine-learning models may improve prediction of length of stay (LOS) and morbidity after surgery. However, few studies include fast-track programs, and most rely on administrative coding with limited follow-up and information on
Externí odkaz:
https://doaj.org/article/1864298286a649cea4f53a18bbca4ba8
Autor:
Mathias L. Heltberg, Christian Michelsen, Emil S. Martiny, Lasse Engbo Christensen, Mogens H. Jensen, Tariq Halasa, Troels C. Petersen
Publikováno v:
Royal Society Open Science, Vol 9, Iss 9 (2022)
The modelling of pandemics has become a critical aspect in modern society. Even though artificial intelligence can help the forecast, the implementation of ordinary differential equations which estimate the time development in the number of susceptib
Externí odkaz:
https://doaj.org/article/af86e2ae74004f25a5bb33ca8b870b48
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The transcription factor NF-κB plays a vital role in the control of the immune system, and following stimulation with TNF-α its nuclear concentration shows oscillatory behaviour. How environmental factors, in particular temperature, can control the
Externí odkaz:
https://doaj.org/article/434e5909814b4cc598e01af5bf02c241
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
It is becoming clear that the dynamics of transcription factors may be important for gene regulation. Here, the authors study the implications of oscillatory and chaotic dynamics of NF-κB and demonstrate that it allows a degree of control of gene ex
Externí odkaz:
https://doaj.org/article/bec13c5bbbb440a98ed977675cd73994
Publikováno v:
Physical Review Research, Vol 3, Iss 3, p 033041 (2021)
Neurons are traditionally grouped in two excitability classes, which correspond to two different responses to external inputs, called phase response curves (PRCs). In this paper we have considered a network of two neural populations with delayed coup
Externí odkaz:
https://doaj.org/article/54f794ec6de94b1a993995803897e6e7
Publikováno v:
Physical Review Research, Vol 2, Iss 4, p 043078 (2020)
Modern biological techniques such as Hi-C permit one to measure probabilities that different chromosomal regions are close in space. These probabilities can be visualized as matrices called contact maps. In this paper, we introduce a multifractal ana
Externí odkaz:
https://doaj.org/article/25ae3737d2894673a1b1fea94bd20599
Autor:
Silas Boye Nissen, Marta Perera, Javier Martin Gonzalez, Sophie M Morgani, Mogens H Jensen, Kim Sneppen, Joshua M Brickman, Ala Trusina
Publikováno v:
PLoS Biology, Vol 15, Iss 7, p e2000737 (2017)
Early mammalian development is both highly regulative and self-organizing. It involves the interplay of cell position, predetermined gene regulatory networks, and environmental interactions to generate the physical arrangement of the blastocyst with
Externí odkaz:
https://doaj.org/article/4ca8e980dd604296bab37e5d629be73a
Autor:
Mathias S. Heltberg, Yuanxu Jiang, Yingying Fan, Zhibo Zhang, Malthe S. Nordentoft, Wei Lin, Long Qian, Qi Ouyang, Mogens H. Jensen, Ping Wei
Publikováno v:
Cell Systems. 14:382-391.e5