Chronic exposure to incretin metabolites GLP-1(9-36) and GIP(3-42) affect islet morphology and beta cell health in high fat fed mice.

Autor: Sridhar A; Biomedical Sciences Research Institute, Diabetes Research Centre, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, UK. Electronic address: a.sridhar@ulster.ac.uk., Khan D; Biomedical Sciences Research Institute, Diabetes Research Centre, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, UK., Babu G; Biomedical Sciences Research Institute, Diabetes Research Centre, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, UK., Irwin N; Biomedical Sciences Research Institute, Diabetes Research Centre, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, UK., Gault VA; Biomedical Sciences Research Institute, Diabetes Research Centre, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, UK., Flatt PR; Biomedical Sciences Research Institute, Diabetes Research Centre, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, UK., Moffett CR; Biomedical Sciences Research Institute, Diabetes Research Centre, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, UK.

Publikováno v: Peptides [Peptides] 2024 Aug; Vol. 178, pp. 171254. Date of Electronic Publication: 2024 May 28.

RYGB surgery has modest effects on intestinal morphology and gut hormone populations in the bypassed biliopancreatic limb but causes reciprocal changes in GLP-2 and PYY in the alimentary limb.

Autor: Sridhar A; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, N. Ireland, United Kingdom., Khan D; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, N. Ireland, United Kingdom., Elliott JA; Department of Surgery, Trinity Centre for Health Sciences and St. James's Hospital, Dublin, Ireland., Naughton V; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, N. Ireland, United Kingdom., Flatt PR; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, N. Ireland, United Kingdom., Irwin N; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, N. Ireland, United Kingdom., Moffett CR; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, N. Ireland, United Kingdom.

Publikováno v: PloS one [PLoS One] 2023 May 25; Vol. 18 (5), pp. e0286062. Date of Electronic Publication: 2023 May 25 (Print Publication: 2023).

Differential effects of RYGB surgery and best medical treatment for obesity-diabetes on intestinal and islet adaptations in obese-diabetic ZDSD rats.

Autor: Sridhar A; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, United Kingdom., Khan D; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, United Kingdom., Abdelaal M; Diabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland., Elliott JA; Department of Surgery, Trinity Centre for Health Sciences and St. James's Hospital, Dublin, Ireland., Naughton V; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, United Kingdom., Flatt PR; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, United Kingdom., Le Roux CW; Diabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland., Docherty NG; Diabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland., Moffett CR; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, United Kingdom.

Publikováno v: PloS one [PLoS One] 2022 Sep 22; Vol. 17 (9), pp. e0274788. Date of Electronic Publication: 2022 Sep 22 (Print Publication: 2022).

Unraveling the Complexity and Advancements of Transdifferentiation Technologies in the Biomedical Field and Their Potential Clinical Relevance.

Autor: Mishra, Purusottam, Biesiada, Izabella, Gupta, Payal, Ghavami, Saeid, Markowski, Jarosław, Łos, Marek J.

Publikováno v: Archivum Immunologiae & Therapiae Experimentalis; Jan2025, Vol. 73 Issue 1, p1-23, 23p

Unraveling the Complexity and Advancements of Transdifferentiation Technologies in the Biomedical Field and Their Potential Clinical Relevance.

Autor: Mishra P; Biotechnology Center, Silesian University of Technology, Gliwice, Poland., Biesiada I; Biotechnology Center, Silesian University of Technology, Gliwice, Poland., Gupta P; Department of Biotechnology, Graphic Era (Deemed to be University), Dehradun, India., Ghavami S; Department of Human Anatomy and Cell Science, Max Rady College of Medicine, Rady Faculty of Health Sciences, Research Institutes of Oncology and Hematology, Cancer Care Manitoba-University of Manitoba, Winnipeg, Canada.; Faculty of Medicine in Zabrze, University of Technology in Katowice, Zabrze, Poland., Markowski J; Department of Laryngology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland., Łos MJ; Biotechnology Center, Silesian University of Technology, Gliwice, Poland.; Department of Pathology, Pomeranian Medical University, Szczecin, Poland.

Publikováno v: Archivum immunologiae et therapiae experimentalis [Arch Immunol Ther Exp (Warsz)] 2024 Dec 05; Vol. 73 (1). Date of Electronic Publication: 2024 Dec 05 (Print Publication: 2025).