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The RNA-binding protein QKI controls alternative splicing in vascular cells, producing an effective model for therapy

Autor: Caines, Rachel, Cochrane, Amy, Kelaini, Sophia, Gonzalez, Marta Vila, Yang, Chunbo, Eleftheriadou, Magdalini, Moez, Arya, Stitt, Alan W, Zeng, Lingfang, Grieve, David J, Margariti, Andriana

Publikováno v: Caines, R, Cochrane, A, Kelaini, S, Gonzalez, M V, Yang, C, Eleftheriadou, M, Moez, A, Stitt, A W, Zeng, L, Grieve, D J & Margariti, A 2019, ' The RNA-binding protein QKI controls alternative splicing in vascular cells, producing an effective model for therapy ', Journal of Cell Science . https://doi.org/10.1242/jcs.230276

Rationale: Endothelial Cell (ECs) and Vascular Smooth Muscle Cell (VSMCs) dysfunction is central to Cardiovascular Disease pathology. Stem cell therapy holds great promise, but greater understanding of mechanisms underpinning vascular cell differenti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2607::8aec333b4bb8b5e896c40bf8e8904fe9
https://pure.qub.ac.uk/en/publications/the-rnabinding-protein-qki-controls-alternative-splicing-in-vascular-cells-producing-an-effective-model-for-therapy(9654419d-7f59-475f-af22-2db3d63a16aa).html

Endothelial cell Nox4 is an important regulator of cardiac ROS signaling and adverse remodeling in experimental diabetes

Autor: Gill, Eleanor, Edgar, Kevin, Hargey, Ciaran, Moez, Arya, Wilson, Adam, Patterson, Ellen, Wong, Xin Ni June, Curtis, Tim, Grieve, David

Publikováno v: In Journal of Molecular and Cellular Cardiology March 2020 140 Supplement:36-36

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The RNA-binding protein QKI controls alternative splicing in vascular cells, producing an effective model for therapy.

Autor: Caines R; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL., Cochrane A; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL., Kelaini S; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL., Vila-Gonzalez M; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL., Yang C; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL., Eleftheriadou M; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL., Moez A; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL., Stitt AW; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL., Zeng L; Cardiovascular Division, King's College London, London SE5 9NU, UK., Grieve DJ; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL., Margariti A; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL a.margariti@qub.ac.uk.

Publikováno v: Journal of cell science [J Cell Sci] 2019 Aug 15; Vol. 132 (16). Date of Electronic Publication: 2019 Aug 15.