Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Moeno, Kume"'
Autor:
Moeno Kume, Ayesha Ahmad, Stephanie Shiers, Michael D. Burton, Kathryn A. DeFea, Josef Vagner, Gregory Dussor, Scott Boitano, Theodore J. Price
Publikováno v:
The Journal of Pain. 24:605-616
Given the limited options and often harmful side effects of current analgesics and the suffering caused by the opioid crisis, new classes of pain therapeutics are needed. Protease-activated receptors (PARs), particularly PAR2, are implicated in a var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a29fc0d7e3afb63b1cdbfda3e539bad
https://doi.org/10.1016/j.jpain.2022.11.006
https://doi.org/10.1016/j.jpain.2022.11.006
Autor:
Ishwarya Sankaranarayanan, Diana Tavares-Ferreira, Lucy He, Moeno Kume, Juliet M. Mwirigi, Torsten M. Madsen, Kenneth A. Petersen, Gordon Munro, Theodore J. Price
Publikováno v:
The Journal of Pain. 24:555-567
Chemotherapy-induced peripheral neuropathy is a challenging condition to treat, and arises due to severe, dose-limiting toxicity of chemotherapeutic drugs such as paclitaxel. This often results in debilitating sensory and motor deficits that are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09db4b5b2f3cd999e678c46cd717123
https://doi.org/10.1016/j.jpain.2022.10.015
https://doi.org/10.1016/j.jpain.2022.10.015
Autor:
Hillary V. Schiff, Candy M. Rivas, William P. Pederson, Estevan Sandoval, Samuel Gillman, Joy Prisco, Moeno Kume, Gregory Dussor, Josef Vagner, Julie G. Ledford, Theodore J. Price, Kathryn A. DeFea, Scott Boitano
Publikováno v:
British Journal of Pharmacology. 180:667-680
Asthma is a heterogenous disease strongly associated with inflammation that has many different causes and triggers. Current asthma treatments target symptoms such as bronchoconstriction and airway inflammation. Despite recent advances in biological t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f12b41a8edcf2479b562cc26fc2a78
https://doi.org/10.1111/bph.15903
https://doi.org/10.1111/bph.15903
Autor:
Jamie K. Moy, Thomas Szabo-Pardi, Dipti V. Tillu, Salim Megat, Grishma Pradhan, Moeno Kume, Marina N. Asiedu, Michael D. Burton, Gregory Dussor, Theodore J. Price
Publikováno v:
Neurobiology of Pain, Vol 5, Iss , Pp - (2019)
Brain-derived neurotrophic factor (BDNF) signaling through its cognate receptor, TrkB, is a well-known promoter of synaptic plasticity at nociceptive synapses in the dorsal horn of the spinal cord. Existing evidence suggests that BDNF/TrkB signaling
Externí odkaz:
https://doaj.org/article/ac4227b8cd9546568e79bfd65ba62b36
Autor:
Moeno Kume, Ayesha Ahmad, Kathryn A. DeFea, Josef Vagner, Gregory Dussor, Scott Boitano, Theodore J. Price
Background and PurposeChemotherapy-Induced Peripheral Neuropathy (CIPN) is a common, dose-limiting side effect of cancer therapy. Protease-activated receptor 2 (PAR2) is implicated in a variety of pathologies, including CIPN. In this study, we demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b109c02cfeb9ff892671800602f005a7
https://doi.org/10.1101/2023.02.12.528175
https://doi.org/10.1101/2023.02.12.528175
Autor:
Ishwarya Sankaranarayanan, Diana Tavares-Ferreira, Lucy He, Moeno Kume, Juliet Mwirigi, Torsten M. Madsen, Kenneth A. Petersen, Gordon Munro, Theodore J. Price
Chemotherapy-induced peripheral neuropathy (CIPN) is a challenging condition to treat, and arises due to severe, dose-limiting toxicity of chemotherapeutic drugs such as paclitaxel. This often results in debilitating sensory and motor deficits that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61c3fc0a1b30252f30a55ac4f5f73eef
https://doi.org/10.1101/2022.09.13.507857
https://doi.org/10.1101/2022.09.13.507857
Autor:
Hajira Elahi, Shayne Hassler, Stephanie I. Shiers, Jessica Loucks, Rohita Arjarapu, Moeno Kume, Matthew Dalva, Theodore J. Price
Publikováno v:
The Journal of Pain. 24:8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc36adb4ea863678d0d826693fc2b8cd
https://doi.org/10.1016/j.jpain.2023.02.038
https://doi.org/10.1016/j.jpain.2023.02.038
Autor:
Candler Paige, Isabel Plasencia-Fernandez, Moeno Kume, Melina Papalampropoulou-Tsiridou, Louis-Etienne Lorenzo, Eric T. David, Lucy He, Galo L. Mejia, Christopher Driskill, Francesco Ferrini, Andrew L. Feldhaus, Leon F. Garcia-Martinez, Armen N. Akopian, Yves De Koninck, Gregory Dussor, Theodore J. Price
Publikováno v:
J Neurosci
We aimed to investigate a sexually dimorphic role of calcitonin gene-related peptide (CGRP) in rodent models of pain. Based on findings in migraine where CGRP has a preferential pain-promoting effect in female rodents, we hypothesized that CGRP antag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b99aaaa249bfec37f600d2341ae392
https://pubmed.ncbi.nlm.nih.gov/35058371
https://pubmed.ncbi.nlm.nih.gov/35058371
Autor:
Gregory Dussor, Moeno Kume, Pradipta R. Ray, Theodore J. Price, Eric T. David, Andi Wangzhou, Dhananjay K. Naik, Candler Paige, Sanjay V. Neerukonda
Publikováno v:
Sci Signal
In the peripheral nervous system, ligand-receptor interactions between cells and neurons shape sensory experience, including pain. We set out to identify the potential interactions between sensory neurons and peripheral cell types implicated in disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e3ffe1845d71395a2fe35557531ed1
https://europepmc.org/articles/PMC8097872/
https://europepmc.org/articles/PMC8097872/
Autor:
Benjamin D. Rivera, Nakleh Mseeh, Moeno Kume, Ayesha Ahmad, Breya P. Ludwig, Josef Vagner, Changyu Jiang, Marvin T. Nieman, Ru-Rong Ji, Scott Boitano, Gregory Dussor, Pradipta R. Ray, Shayne N. Hassler, Thomas Van de Ven, Alexander Chamessian, Juliet Mwirigi, Theodore J. Price
Publikováno v:
J Pain
The protease activated receptor (PAR) family is a group of G-protein coupled receptors (GPCRs) activated by proteolytic cleavage of the extracellular domain. PARs are expressed in a variety of cell types with crucial roles in homeostasis, immune resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb5f29a66d4459199b03dec06c750b7a
https://europepmc.org/articles/PMC8197731/
https://europepmc.org/articles/PMC8197731/