Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Moein, Yaqubi"'
Autor:
Afsaneh Shirani, Nil Saez-Calveras, Jack P. Antel, Moein Yaqubi, Wayne Moore, Amy L. Brewster, Olaf Stuve
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Multiple lines of evidence suggest a role of inflammation in epilepsy. Seizure incidence in patients with multiple sclerosis (MS) is twofold to threefold higher than the age-matched general population. Objectives: To explore the associati
Externí odkaz:
https://doaj.org/article/8935f835fd054892b36d48d14c69d1c2
Autor:
Marie-France Dorion, Diana Casas, Irina Shlaifer, Moein Yaqubi, Peter Fleming, Nathan Karpilovsky, Carol X.-Q. Chen, Michael Nicouleau, Valerio E. C. Piscopo, Emma J. MacDougall, Aeshah Alluli, Taylor M. Goldsmith, Alexandria Schneider, Samuel Dorion, Nathalia Aprahamian, Adam MacDonald, Rhalena A. Thomas, Roy W. R. Dudley, Jeffrey A. Hall, Edward A. Fon, Jack P. Antel, Jo Anne Stratton, Thomas M. Durcan, Roberta La Piana, Luke M. Healy
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-26 (2024)
Abstract Background Induced pluripotent stem cell-derived microglia (iMGL) represent an excellent tool in studying microglial function in health and disease. Yet, since differentiation and survival of iMGL are highly reliant on colony-stimulating fac
Externí odkaz:
https://doaj.org/article/aa6be16cdc4045c0b1747096bb52aa8a
Autor:
Chao Weng, Adam M.R. Groh, Moein Yaqubi, Qiao-Ling Cui, Jo Anne Stratton, G. R. Wayne Moore, Jack P. Antel
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 5, Pp 1336-1349 (2025)
Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous system. Recent evidence has challenged the classical view of the functionally static mature oligodendroc
Externí odkaz:
https://doaj.org/article/e0be70ed53e9484c8f42390661cc299e
Autor:
Milton Guilherme Forestieri Fernandes, Abdulshakour Mohammadnia, Florian Pernin, Laura Eleonora Schmitz-Gielsdorf, Caroline Hodgins, Qiao-Ling Cui, Moein Yaqubi, Manon Blain, Jeffery Hall, Roy Dudley, Myriam Srour, Stephanie E. J. Zandee, Wendy Klement, Alexandre Prat, Jo Anne Stratton, Moses Rodriguez, Tanja Kuhlmann, Wayne Moore, Timothy E. Kennedy, Jack P. Antel
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Oligodendrocyte (OL) injury and loss are central features of evolving lesions in multiple sclerosis. Potential causative mechanisms of OL loss include metabolic stress within the lesion microenvironment. Here we use the injury response of pr
Externí odkaz:
https://doaj.org/article/0b83309164e245e4aea64f44e59886dc
Autor:
Moein Yaqubi, Adam M. R. Groh, Marie-France Dorion, Elia Afanasiev, Julia Xiao Xuan Luo, Hadi Hashemi, Sarthak Sinha, Nicholas W. Kieran, Manon Blain, Qiao-Ling Cui, Jeff Biernaskie, Myriam Srour, Roy Dudley, Jeffery A. Hall, Joshua A. Sonnen, Nathalie Arbour, Alexandre Prat, Jo Anne Stratton, Jack Antel, Luke M. Healy
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-18 (2023)
Abstract Background Microglia are tissue resident macrophages with a wide range of critically important functions in central nervous system development and homeostasis. Method In this study, we aimed to characterize the transcriptional landscape of e
Externí odkaz:
https://doaj.org/article/af75dc06fd684de888eae1e621a52263
Autor:
Shannon Tansley, Sonali Uttam, Alba Ureña Guzmán, Moein Yaqubi, Alain Pacis, Marc Parisien, Haley Deamond, Calvin Wong, Oded Rabau, Nicole Brown, Lisbet Haglund, Jean Ouellet, Carlo Santaguida, Alfredo Ribeiro-da-Silva, Soroush Tahmasebi, Masha Prager-Khoutorsky, Jiannis Ragoussis, Ji Zhang, Michael W. Salter, Luda Diatchenko, Luke M. Healy, Jeffrey S. Mogil, Arkady Khoutorsky
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Microglia subpopulations may differentially contribute to pain. Here, the authors show that peripheral nerve injury induces time- and sex-specific transcriptional changes in mouse spinal cord microglia subpopulations and that ApoE is linked to neurop
Externí odkaz:
https://doaj.org/article/da0c9468505d43fa969f7922829123de
Autor:
Ali Motahharynia, Shiva Moein, Farnoush Kiyanpour, Kobra Moradzadeh, Moein Yaqubi, Yousof Gheisari
Publikováno v:
npj Systems Biology and Applications, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract Olfactory receptors (ORs) which are mainly known as odor-sensors in the olfactory epithelium are shown to be expressed in several non-sensory tissues. Despite the specified role of some of these receptors in normal physiology of the kidney,
Externí odkaz:
https://doaj.org/article/14d4bc8ac09040a1a9f983cc78c79e0c
Autor:
Milton Guilherme Forestieri Fernandes, Julia Xiao Xuan Luo, Qiao-Ling Cui, Kelly Perlman, Florian Pernin, Moein Yaqubi, Jeffery A. Hall, Roy Dudley, Myriam Srour, Charles P. Couturier, Kevin Petrecca, Catherine Larochelle, Luke M. Healy, Jo Anne Stratton, Timothy E. Kennedy, Jack P. Antel
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Milton Fernandes et al. combine single cell RNA-sequencing and functional assays to show that human oligodendrocytes exhibit an age-dependent resistance to apoptosis. Their findings have important implications for the pathology and treatment of myeli
Externí odkaz:
https://doaj.org/article/2f5ecb99de5f4c29b216220d02b72b5a
Autor:
Shantala A. Hari Dass, Kathryn McCracken, Irina Pokhvisneva, Lawrence M. Chen, Elika Garg, Thao T.T. Nguyen, Zihan Wang, Barbara Barth, Moein Yaqubi, Lisa M. McEwen, Julie L. MacIsaac, Josie Diorio, Michael S. Kobor, Kieran J. O'Donnell, Michael J. Meaney, Patricia P. Silveira
Publikováno v:
EBioMedicine, Vol 42, Iss , Pp 188-202 (2019)
Background: Activation of brain insulin receptors modulates reward sensitivity, inhibitory control and memory. Variations in the functioning of this mechanism likely associate with individual differences in the risk for related mental disorders (atte
Externí odkaz:
https://doaj.org/article/0a930b227bbe495788b5d17b8ed4a14e
Autor:
Marie‐France Dorion, Moein Yaqubi, Hunter J. Murdoch, Jeffery A. Hall, Roy Dudley, Jack P. Antel, Thomas Martin Durcan, Luke Michael Healy
Publikováno v:
Glia. 71:1278-1293
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e430f3551f60d092272fe60897aafcf
https://doi.org/10.1002/glia.24338
https://doi.org/10.1002/glia.24338