Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Moeez Ghani Rathore"'
Autor:
Alberto eAnel, Juan Ignacio Aguiló, Elena eCatalán, Johan eGaraude, Moeez Ghani Rathore, Julián ePardo, Martín eVillalba
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
The protein kinase C-theta (PKCtheta), which is essential for T cell function and survival, is also required for efficient anti-tumor immune surveillance. Natural killer (NK) cells, which express PKCtheta, play a prominent role in this process, mainl
Externí odkaz:
https://doaj.org/article/772c76b28aa6499bb9df8ad398b9e37f
Autor:
Zigang Dong, Scott M. Lippman, Hitoshi Ashida, Ann M. Bode, Moeez Ghani Rathore, Mee-Hyun Lee, Xiaoyu Chang, Weiya Ma, Ke Yao, Kanamata Reddy, Tatyana A. Zykova, Naomi Oi, Ting Wang, Hanyong Chen, Keke Wang, Ge Gao, Mangaladoss Fredimoses, Qiushi Wang, Tianshun Zhang
Malignant melanoma is an aggressive tumor of the skin and still lacks effective preventive and therapeutic treatments. In melanoma, both the BRAF/MEK/ERK and PI3-K/AKT signaling pathways are constitutively activated through multiple mechanisms, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e305aa01ea54c2574cbcd9598bb3b5
https://doi.org/10.1158/1940-6207.c.6547082
https://doi.org/10.1158/1940-6207.c.6547082
Autor:
Moeez Ghani Rathore, Michelle Wright, Wei Huang, Derek Taylor, Yamu Li, Jordan Winter, Zhenghe Wang, John Greenwood, Stephen Moss, Rui Wang
Publikováno v:
Cancer Research. 83:3636-3636
Background: 25% of patients diagnosed with colorectal cancer (CRC) have liver metastasis at presentation, and ~80% of all metastatic CRC are developed in the liver. We previously reported that liver endothelial cells (ECs), a key component of the liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::536c90eb1555ad05519c4abeaa0e9c97
https://doi.org/10.1158/1538-7445.am2023-3636
https://doi.org/10.1158/1538-7445.am2023-3636
Autor:
Kanamata Reddy, Ann M. Bode, Tianshun Zhang, Zigang Dong, Xiaoyu Chang, Qiushi Wang, Seung-Ho Shin, Moeez Ghani Rathore, H. S. Chen, Wei-Ya Ma
Publikováno v:
Theranostics. 10:9721-9740
Rationale: Melanoma is an aggressive tumor of the skin and drug resistance is still a major problem in melanoma therapy. Novel targets and effective agents to overcome drug resistant melanoma are urgently needed in clinical therapy. Methods: Gene Exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b91c4b5e3112ed40893e7625fd221a93
https://doi.org/10.7150/thno.44342
https://doi.org/10.7150/thno.44342
Autor:
Jordan M. Winter, Joseph Willis, Fan Fan, Zhenghe Wang, Rajat Bhattacharya, Michel’le Wright, Lee M. Ellis, Sanford D. Markowitz, Ali Vaziri-Gohar, Rui Wang, Moeez Ghani Rathore
We previously showed that human epidermal growth factor receptor 3 (HER3, also known as ERBB3) is a key mediator in liver endothelial cell (EC) promoting colorectal cancer (CRC) growth and chemoresistance, and suggested HER3-targeted therapy as a str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::652a19f48fd06e1c95b9d676519a9304
https://doi.org/10.21203/rs.3.rs-745208/v1
https://doi.org/10.21203/rs.3.rs-745208/v1
Autor:
Marcel Deckert, Virginie Prod'homme, Mélanie Tichet, Frédéric Larbret, Christophe Girard, Stéphane Audebert, Mickaël Ohanna, E. Garcia, Henri Montaudié, Moeez Ghani Rathore, Maeva Gesson, Sophie Tartare-Deckert, R. Ben Jouira, J.-P. Lacour
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2019, 38 (30), pp.5873-5889. ⟨10.1038/s41388-019-0848-9⟩
Oncogene, 2019, 38 (30), pp.5873-5889. ⟨10.1038/s41388-019-0848-9⟩
Oncogene, Nature Publishing Group, 2019, 38 (30), pp.5873-5889. ⟨10.1038/s41388-019-0848-9⟩
Oncogene, 2019, 38 (30), pp.5873-5889. ⟨10.1038/s41388-019-0848-9⟩
International audience; Cutaneous melanoma is one of the most aggressive cancers characterized by a high plasticity, a propensity for metastasis, and drug resistance. Melanomas are composed of phenotypically diverse subpopulations of tumor cells with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1f426491b7b515815fcd061ad2e91e
https://doi.org/10.1038/s41388-019-0848-9
https://doi.org/10.1038/s41388-019-0848-9
Autor:
Moeez Ghani Rathore, Wei Zhang, Michel'le Wright, Jordan Winter, Yamu Li, Zhenghe Wang, Rui Wang
Publikováno v:
Cancer Research. 82:3177-3177
Background: Liver is the most common site of developing distant metastasis in colorectal cancer (CRC). Patients with metastatic CRC (mCRC) have a 5-year survival rate at 14%. We previously showed that liver endothelial cells (EC), a key component of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c84e4304d474f07dce28782c0dec715
https://doi.org/10.1158/1538-7445.am2022-3177
https://doi.org/10.1158/1538-7445.am2022-3177
Autor:
Xiaoyu, Chang, Tianshun, Zhang, Qiushi, Wang, Moeez Ghani, Rathore, Kanamata, Reddy, Hanyong, Chen, Seung Ho, Shin, Wei-Ya, Ma, Ann M, Bode, Zigang, Dong
Publikováno v:
Theranostics
Rationale: Melanoma is an aggressive tumor of the skin and drug resistance is still a major problem in melanoma therapy. Novel targets and effective agents to overcome drug resistant melanoma are urgently needed in clinical therapy. Methods: Gene Exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60abe331dd0c9985b18e0f659bfa0ffe
https://pubmed.ncbi.nlm.nih.gov/32863956
https://pubmed.ncbi.nlm.nih.gov/32863956
Autor:
Abhijit Chakraborty, Raja Dey, Faisal Aziz, Zigang Dong, Le Thi My Le, Moeez Ghani Rathore, Aalekhya Biswas, Ann M. Bode, Tianshun Zhang, Eunmiri Roh
Publikováno v:
Oncotarget
Background: The Timeless (TIM) and its interacting partner TIPIN protein complex is well known for its role in replication checkpoint and normal DNA replication processes. TIM appears to be an essential component of the DNA damage response. Recent st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ea8365210df280c63c0ac9dfc36130
https://doi.org/10.2139/ssrn.3526288
https://doi.org/10.2139/ssrn.3526288
Autor:
Mee-Hyun Lee, Xiaoyu Chang, Tatyana A. Zykova, Scott M. Lippman, Naomi Oi, Wei-Ya Ma, Qiushi Wang, Tianshun Zhang, H. S. Chen, Zigang Dong, Ke Yao, Kanamata Reddy, Hitoshi Ashida, Ge Gao, Keke Wang, Moeez Ghani Rathore, Ting Wang, Ann M. Bode, Mangaladoss Fredimoses
Publikováno v:
Cancer Prevention Research. 11:607-620
Malignant melanoma is an aggressive tumor of the skin and still lacks effective preventive and therapeutic treatments. In melanoma, both the BRAF/MEK/ERK and PI3-K/AKT signaling pathways are constitutively activated through multiple mechanisms, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::304d9ff9b2fc258537a7249397a0a68f
https://doi.org/10.1158/1940-6207.capr-18-0092
https://doi.org/10.1158/1940-6207.capr-18-0092