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Inducible developmental reprogramming redefines commitment to sexual development by malaria parasites

Autor: Kent, Robyn S., Modrzynska, Katarzyna K., Cameron, Rachael, Philip, Nisha, Billker, Oliver, Waters, Andrew P.

During malaria infection, Plasmodium spp. parasites cyclically invade red blood cells and can follow two different developmental pathways. They can either replicate asexually to sustain the infection, or differentiate into gametocytes, the sexual sta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::99a95dad722eacf51579fa35e2dd07b0
https://eprints.gla.ac.uk/161125/7/161125.pdf

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BCKDH: The Missing Link in Apicomplexan Mitochondrial Metabolism Is Required for Full Virulence of Toxoplasma gondii and Plasmodium berghei

Autor: Oppenheim, Rebecca D., Creek, Darren J., Macrae, James I., Modrzynska, Katarzyna K., Pino, Paco, Limenitakis, Julien, Polonais, Valerie, Seeber, Frank, Barrett, Michael P., Billker, Oliver, McConville, Malcolm J., Soldati-Favre, Dominique, Sibley, L. David

Publikováno v: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2014, 10 (7), pp.25032958. ⟨10.1371/journal.ppat.1004263⟩
PLoS Pathogens, Public Library of Science, 2014, 10 (7), pp.e1004263
PLOS Pathogens, Vol. 10, No 7 (2014) P. e1004263
PLoS Pathogens, 2014, 10 (7), pp.25032958. ⟨10.1371/journal.ppat.1004263⟩
PLoS Pathogens, Vol 10, Iss 7, p e1004263 (2014)

While the apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii are thought to primarily depend on glycolysis for ATP synthesis, recent studies have shown that they can fully catabolize glucose in a canonical TCA cycle. However, these pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65cb625f9b806af17b9b57ef4f0d844
https://hal.archives-ouvertes.fr/hal-01112521

BCKDH: The Missing Link in Apicomplexan Mitochondrial Metabolism Is Required for Full Virulence of Toxoplasma gondii and Plasmodium berghei.

Autor: Oppenheim, Rebecca D., Creek, Darren J., Macrae, James I., Modrzynska, Katarzyna K., Pino, Paco, Limenitakis, Julien, Polonais, Valerie, Seeber, Frank, Barrett, Michael P., Billker, Oliver, McConville, Malcolm J., Soldati-Favre, Dominique

Publikováno v: PLoS Pathogens; Jul2014, Vol. 10 Issue 7, p1-18, 18p