Increased NF-κB Activity and Decreased Wnt/β-Catenin Signaling Mediate Reduced Osteoblast Differentiation and Function in ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mice

Autor: Le Henaff, Carole, Mansouri, Rafik, Modrowski, Dominique, Zarka, Mylène, Geoffroy, Valérie, Marty, Caroline, Tarantino, Nadine, Laplantine, Emmanuel, Marie, Pierre J.

Publikováno v: In Journal of Biological Chemistry 17 July 2015 290(29):18009-18017

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Chapter 4 - Deregulation of osteoblast differentiation in primary bone cancers

Autor: Marie, Pierre J., Fromigué, Olivia, Modrowski, Dominique

Publikováno v: In Bone Cancer Edition: Second Edition. 2015:39-54

Correction: Osteoblastic heparan sulfate glycosaminoglycans control bone remodeling by regulating Wnt signaling and the crosstalk between bone surface and marrow cells.

Autor: Mansouri, Rafik, Jouan, Yohann, Hay, Eric, Blin-Wakkach, Claudine, Frain, Monique, Ostertag, Agnès, Le Henaff, Carole, Marty, Caroline, Geoffroy, Valérie, Marie, Pierre J, Cohen-Solal, Martine, Modrowski, Dominique

Publikováno v: Cell Death & Disease; Aug2018, Vol. 9 Issue 8, p1-15, 15p

RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation

Autor: Fromigue, Olivia, Hay, Eric, Modrowski, Dominique, Bouvet, Sophie, Jacquel, Arnaud, Auberger, Patrick, Marie, Pierre

Publikováno v: Cell Death and Differentiation
Cell Death and Differentiation, Nature Publishing Group, 2006, 13 (11), pp.1845-1856. ⟨10.1038/sj.cdd.4401873⟩

Osteosarcoma is the most common primary bone tumour in young adults. Despite improved prognosis, resistance to chemotherapy remains responsible for failure of osteosarcoma treatment. The identification of signals that promote apoptosis may provide cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::6fbd3741985661b9c1c81345ea7c94e5
https://doi.org/10.1038/sj.cdd.4401873