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Akademický článek

Gene expression in IFN-g-activated murine macrophages

Autor: Pereira C.A., Modolell M., Frey J.R., Lefkovits I.

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 37, Iss 12, Pp 1795-1809 (2004)

Macrophages are critical for natural immunity and play a central role in specific acquired immunity. The IFN-gamma activation of macrophages derived from A/J or BALB/c mice yielded two different patterns of antiviral state in murine hepatitis virus 3

Externí odkaz: https://doaj.org/article/2e2cf9a2d64d4b2e9f98a318782da2aa

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Malnutrition in Healthy Individuals Results in Increased Mixed Cytokine Profiles, Altered Neutrophil Subsets and Function

Autor: Takele, Y., Adem, E., Getahun, M., Tajebe, F., Kiflie, A., Hailu, A., Raynes, J., Mengesha, B., Ayele, T. A., Shkedy, Z., Lemma, M., Diro, E., Toulza, F., Modolell, M., Munder, M., Müller, I., Kropf, P.

Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0157919 (2016)
PLoS ONE

Malnutrition is commonly associated with increased infectious disease susceptibility and severity. Whereas malnutrition might enhance the incidence of disease as well as its severity, active infection can in turn exacerbate malnutrition. Therefore, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::35d59793946607b1489dcfc27c598941
https://researchonline.lshtm.ac.uk/id/eprint/2805696/1/journal.pone.0157919.PDF

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Th1/Th2-Regulated Expression of Arginase Isoforms in Murine Macrophages and Dendritic Cells

Autor: Munder, M., Eichmann, K., Morán, J. M., Francisco Centeno, Soler, G., Modolell, M.

Publikováno v: Scopus-Elsevier

Activated murine macrophages metabolize arginine by two alternative pathways involving the enzymes inducible NO synthase (iNOS) or arginase. The balance between the two enzymes is competitively regulated by Th1 and Th2 T helper cells via their secret

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92022f50132ff5158241086c9ee9901
https://doi.org/10.4049/jimmunol.163.7.3771

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Differential impact of L-arginine deprivation on the activation and effector functions of T cells and macrophages

Autor: Choi, B-S, Martinez-Falero, I Clara, Corset, C, Munder, M, Modolell, M, Müller, I, Kropf, P

The metabolism of the amino acid L-arginine is emerging as a crucial mechanism for the regulation of immune responses. Here, we characterized the impact of L-arginine deprivation on T cell and macrophage (MPhi) effector functions: We show that wherea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::5d14d3ec5920e342c59bcaa187d37b08
https://researchonline.lshtm.ac.uk/id/eprint/1637/1/268.full.pdf

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Interferon-gamma regulates nucleoside transport systems in macrophages through signal transduction and activator of transduction factor 1 (STAT1)-dependent and -independent signalling pathways

Autor: Soler C, Felipe A, García-Manteiga J, Serra M, Guillén-Gómez E, Casado FJ, MacLeod C, Modolell M, Pastor-Anglada M, Celada A

Publikováno v: BIOCHEMICAL JOURNAL
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

The expressions of CNT and ENT (concentrative and equilibrative nucleoside transporters) in macrophages are differentially regulated by IFN-gamma (interferon-gamma). This cytokine controls gene expression through STAT1-dependent and/or -independent p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0a15fd3c011a7a79da4d904accb5e674
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=11828

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