Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Modesta Espada"'
Autor:
Dolors Salvatierra, Luis M. Díaz-Guerra, Carlos Jaime, M. Asuncion Ruiz, Carmen Avendaño, M. Teresa Ramos, J. Carlos Menéndez, José M. Pingarrón, Blanca Ocaña, Jose Maria Perez, Modesta Espada
Publikováno v:
Bulletin des Sociétés Chimiques Belges. 104:683-690
The redox properties of a series of 1-azaanthracene-9,10-diones, 1,8-diazaanthracene-9,10-diones, 1,8-diazaanthracene-(1H)2,9,10-triones and 1,8-diazaanthracene-(1H, 8H)2,7,9,10-tetraones have been studied. The results obtained show that the 2-pyrido
Publikováno v:
Tetrahedron. 55:1755-1762
(4S)-2,4-Dimethyl-2,4-dihydro-(1H)-pyrazino[2,1-b]quinazoline-3,6-dione was converted into to the cis-tosylate 2, whose reactivity as an electrophilic glycine template is discussed. It was found that this compound does not give direct SN2-type displa
Autor:
Modesta Espada, Carmen Pedregal, Carmen Dominguez, Stéphane Borrelly, Jesús Ezquerra, S. Richard Baker, Lourdes Prieto
Publikováno v:
Tetrahedron Letters. 39:9305-9308
( 1S,2S,5R,6S )-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740) was synthesised enantiospecifically from a sugar derived enantiomerically pure cyclopentenone. The α-amino acid stereogenic centre was formed by reacting the ketone with ch
Publikováno v:
Tetrahedron. 53:16795-16802
Dialkylation of the title compound occurs regioselectively at C-1. Addition of N,N′-dimethyl-N,N′-propylene urea (DMPU) permits the one-pot synthesis of 1,1-dialkylation products in good yields. The asymmetric induction of the stereogenic C-4 cen
Autor:
Félix L. Buenadicha, Carmen Avendaño, Modesta Espada, Sonsoles Martín-Santamaría, Mónica Söllhuber
Publikováno v:
The Journal of Organic Chemistry. 62:6424-6428
Publikováno v:
Tetrahedron: Asymmetry. 8:511-514
The asymmetric synthesis of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740) 1, a potent and selective group 2 mGluR agonist, has been accomplished starting from the readily available enantiomerically pure cyclopentenone 4. Thus, cycl
Autor:
Lourdes Prieto, Belén Yruretagoyena, William G. Prowse, Carmen Pedregal, Carmen Avendaño, Elena de la Cuesta, Rosario González, Jesús Ezquerra, Modesta Espada
Publikováno v:
Tetrahedron. 51:3271-3278
The synthesis of racemic 3-aminobicyclo[3.3.0]octane-1,3-dicarboxylic acids (2 and 3) which are conformationally constrained ACPD analogues, has been achieved in seven steps starting from the readily available Weiss diketone (4). Partial reduction of
Publikováno v:
Tetrahedron. 51:1253-1258
1-Azaanthracene-2,5,8-triones and 1,8-diazaanthracene-2,7,9,10-tetraones, which are structurally related to diazaquinomycin, are prepared by functionalization of azaathraquinone N-oxides. The complete procedure implies a Diels-Alder reaction as a key
Publikováno v:
Tetrahedron. 50:9505-9510
A procedure is described for the efficient N-oxidation of heterocyclic quinones, which represents a considerable improvement over previous, multi-step methods.
Autor:
Loreto Salazar, Dionisia Sanz, F. Gómez-Beltrán, Rosa Ma Claramunt, Modesta Espada, José Elguero, Ma Rosario Díaz, Santiago García-Granda
Publikováno v:
J. Chem. Soc., Perkin Trans. 2. :377-383
The molecular structures of N-(pyrazol-1-yl) formamide 1[C4H5N3O, orthorhombic, space group P212121, a= 5.269(8). b= 8.039(8). c= 12.79(2), Z= 4] and N-(indazol-1 -yl) formamide, 5[C8H7N3O, monoclinic, space group P21/c, a= 9.065(2). b= 11.089(7), c=