Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Modem, Suhasini"'
Publikováno v:
Oncogene. 21:7187-7194
Sam68 is a target of the c-Src tyrosine kinase. We previously showed that overexpression of Sam68 functionally substitutes for, as well as synergies with, HIV-1 Rev in Rev-response element (RRE)-mediated gene expression and virus replication. Here we
Autor:
Lan Yu Yeh, Karen Artzt, Jian-Ping Yang, T. Raghavendar Reddy, Modem Suhasini, Weidong Xu, Flossie Wong-Staal, Jiang Wu
Publikováno v:
Journal of Biological Chemistry. 277:5778-5784
Overexpression of Sam68 functionally substitutes for, as well as synergizes with, human immunodeficiency virus type 1 (HIV-1) Rev in RRE (Rev response element)-mediated gene expression and virus replication. In addition, COOH-terminal deletion and/or
Autor:
Hengli Tang, Kenneth Frimpong, Christopher D. Goodwin, Jonathan K. L. Mau, Modem Suhasini, Flossie Wong-Staal, Thipparthi R. Reddy, David W. Rose, Weidong Xu
Publikováno v:
Nature Medicine. 5:635-642
The HIV-1 Rev protein facilitates the nuclear export of mRNA containing the Rev response element (RRE) through binding to the export receptor CRM-1. Here we show that a cellular nuclear protein, Sam68 (Src-associated protein in mitosis), specifically
Publikováno v:
Oncogene. 15:1859-1870
During hexamethylene bisactamide (HMBA)-induced differentiation of murine erythroleukemia (MEL) cells erythroid genes are transcriptionally activated while c-myb and several other nuclear proto-oncogenes are down-regulated. Differentiation is inhibit
Publikováno v:
The FASEB Journal. 9:552-558
Nitric oxide (NO) increases cytosolic guanylate cyclase activity and thereby activates the cGMP signal transduction pathway. The cAMP and Ca2+/phospholipid signal transduction pathways activate transcription factors that bind to the cAMP response ele
Autor:
Marjaneh Berjis, Gerry R. Boss, Soha D. Idriss, Immo E. Scheffler, Modem Suhasini, Renate B. Pilz, Jürgen Scheele, Lin Gao
Publikováno v:
Journal of Biological Chemistry. 269:32155-32161
Sodium nitroprusside and sodium nitrite, which generate nitric oxide and increase the intracellular cGMP concentration, and 8-bromo-cGMP, a membrane-permeable cGMP analog, induce myelomonocytic differentiation of HL-60 cells (Boss, G. R. (1989) Proc.
Autor:
Thipparthi R. Reddy, Modem Suhasini
Publikováno v:
Current HIV research. 7(1)
The human immunodeficiency virus (HIV-1) differentially controls viral protein expression at the level of splicing as well as nuclear export of incompletely spliced viral RNA. This process, mediated by the Rev protein, interfaces with cellular compon
Autor:
Renate B. Pilz, Modem Suhasini
Publikováno v:
Oncogene. 18(51)
High levels of c-myb expression are necessary for the proliferation of hematopoietic precursor cells whereas down-regulation of c-myb is required for terminal differentiation; this down-regulation occurs through a conditional block to transcriptional
Publikováno v:
Molecular and cellular biology. 18(12)
Many mitogenic stimuli, including growth factors like epidermal growth factor (EGF), cytokines such as granulocyte-monocyte colony-stimulating factor, and hormones which bind to G-protein-coupled receptors, activate the Ras/mitogen-activated protein
Publikováno v:
Blood. 91(9)
Activation of cyclic adenosine monophosphate (cAMP)-dependent protein kinase (A-kinase) promotes hemoglobin synthesis in several erythropoietin-dependent cell lines, whereas A-kinase–deficient murine erythroleukemia (MEL) cells show impaired hemogl