Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Modem, Suhasini"'
Publikováno v:
Oncogene. 21:7187-7194
Sam68 is a target of the c-Src tyrosine kinase. We previously showed that overexpression of Sam68 functionally substitutes for, as well as synergies with, HIV-1 Rev in Rev-response element (RRE)-mediated gene expression and virus replication. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f8a286c384ee0961bce3773b87f7ce
https://doi.org/10.1038/sj.onc.1205759
https://doi.org/10.1038/sj.onc.1205759
Autor:
Lan Yu Yeh, Karen Artzt, Jian-Ping Yang, T. Raghavendar Reddy, Modem Suhasini, Weidong Xu, Flossie Wong-Staal, Jiang Wu
Publikováno v:
Journal of Biological Chemistry. 277:5778-5784
Overexpression of Sam68 functionally substitutes for, as well as synergizes with, human immunodeficiency virus type 1 (HIV-1) Rev in RRE (Rev response element)-mediated gene expression and virus replication. In addition, COOH-terminal deletion and/or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109cef08f159ae649ebd3ff050050f52
https://doi.org/10.1074/jbc.m106836200
https://doi.org/10.1074/jbc.m106836200
Autor:
Hengli Tang, Kenneth Frimpong, Christopher D. Goodwin, Jonathan K. L. Mau, Modem Suhasini, Flossie Wong-Staal, Thipparthi R. Reddy, David W. Rose, Weidong Xu
Publikováno v:
Nature Medicine. 5:635-642
The HIV-1 Rev protein facilitates the nuclear export of mRNA containing the Rev response element (RRE) through binding to the export receptor CRM-1. Here we show that a cellular nuclear protein, Sam68 (Src-associated protein in mitosis), specifically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c311fbc14206fdb9214a6fe943912c
https://doi.org/10.1038/9479
https://doi.org/10.1038/9479
Publikováno v:
Oncogene. 15:1859-1870
During hexamethylene bisactamide (HMBA)-induced differentiation of murine erythroleukemia (MEL) cells erythroid genes are transcriptionally activated while c-myb and several other nuclear proto-oncogenes are down-regulated. Differentiation is inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865101f4f55f4fcda82b332c19659370
https://doi.org/10.1038/sj.onc.1201530
https://doi.org/10.1038/sj.onc.1201530
Publikováno v:
The FASEB Journal. 9:552-558
Nitric oxide (NO) increases cytosolic guanylate cyclase activity and thereby activates the cGMP signal transduction pathway. The cAMP and Ca2+/phospholipid signal transduction pathways activate transcription factors that bind to the cAMP response ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b3bc6fde1db317bc42884aa1784ddb
https://doi.org/10.1096/fasebj.9.7.7737465
https://doi.org/10.1096/fasebj.9.7.7737465
Autor:
Marjaneh Berjis, Gerry R. Boss, Soha D. Idriss, Immo E. Scheffler, Modem Suhasini, Renate B. Pilz, Jürgen Scheele, Lin Gao
Publikováno v:
Journal of Biological Chemistry. 269:32155-32161
Sodium nitroprusside and sodium nitrite, which generate nitric oxide and increase the intracellular cGMP concentration, and 8-bromo-cGMP, a membrane-permeable cGMP analog, induce myelomonocytic differentiation of HL-60 cells (Boss, G. R. (1989) Proc.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::847a9c72e40332cb5f0a3d9caed67474
https://doi.org/10.1016/s0021-9258(18)31614-4
https://doi.org/10.1016/s0021-9258(18)31614-4
Autor:
Thipparthi R. Reddy, Modem Suhasini
Publikováno v:
Current HIV research. 7(1)
The human immunodeficiency virus (HIV-1) differentially controls viral protein expression at the level of splicing as well as nuclear export of incompletely spliced viral RNA. This process, mediated by the Rev protein, interfaces with cellular compon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf60006816b6d04ffe26f30568a26ca
https://pubmed.ncbi.nlm.nih.gov/19149558
https://pubmed.ncbi.nlm.nih.gov/19149558
Autor:
Renate B. Pilz, Modem Suhasini
Publikováno v:
Oncogene. 18(51)
High levels of c-myb expression are necessary for the proliferation of hematopoietic precursor cells whereas down-regulation of c-myb is required for terminal differentiation; this down-regulation occurs through a conditional block to transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5032c68a732c1c4de189849157a5748c
https://pubmed.ncbi.nlm.nih.gov/10602492
https://pubmed.ncbi.nlm.nih.gov/10602492
Publikováno v:
Molecular and cellular biology. 18(12)
Many mitogenic stimuli, including growth factors like epidermal growth factor (EGF), cytokines such as granulocyte-monocyte colony-stimulating factor, and hormones which bind to G-protein-coupled receptors, activate the Ras/mitogen-activated protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016c357425d46cf15ad40c71859e60dc
https://pubmed.ncbi.nlm.nih.gov/9819386
https://pubmed.ncbi.nlm.nih.gov/9819386
Publikováno v:
Blood. 91(9)
Activation of cyclic adenosine monophosphate (cAMP)-dependent protein kinase (A-kinase) promotes hemoglobin synthesis in several erythropoietin-dependent cell lines, whereas A-kinase–deficient murine erythroleukemia (MEL) cells show impaired hemogl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c306c1e229c981cc5365cf0640f0743
https://pubmed.ncbi.nlm.nih.gov/9558374
https://pubmed.ncbi.nlm.nih.gov/9558374