Emerging Roles for the RNA-Binding Protein HuD (ELAVL4) in Nervous System Diseases.

Autor: Silvestri, Beatrice^1,2 (AUTHOR), Mochi, Michela¹ (AUTHOR), Garone, Maria Giovanna³ (AUTHOR), Rosa, Alessandro^1,2 (AUTHOR) alessandro.rosa@uniroma1.it

Publikováno v: International Journal of Molecular Sciences. Dec2022, Vol. 23 Issue 23, p14606. 13p.

HuD (ELAVL4) gain-of-function impairs neuromuscular junctions and induces apoptosis in in vitro and in vivo models of amyotrophic lateral sclerosis.

Autor: Silvestri B; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Rome, Italy.; Center for Life Nano-& Neuro-Science, Fondazione Istituto Italiano di Tecnologia (IIT), Rome, Italy., Mochi M; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Rome, Italy., Mawrie D; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, PA, USA., de Turris V; Center for Life Nano-& Neuro-Science, Fondazione Istituto Italiano di Tecnologia (IIT), Rome, Italy., Colantoni A; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Rome, Italy.; Center for Life Nano-& Neuro-Science, Fondazione Istituto Italiano di Tecnologia (IIT), Rome, Italy., Borhy B; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Rome, Italy., Medici M; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Rome, Italy., Anderson EN; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, PA, USA., Garone MG; Department of Stem Cell Biology, Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Melbourne, Victoria, Australia., Zammerilla CP; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, PA, USA., Pandey UB; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, PA, USA.; Children's Neuroscience Institute, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA USA., Rosa A; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Rome, Italy.; Center for Life Nano-& Neuro-Science, Fondazione Istituto Italiano di Tecnologia (IIT), Rome, Italy.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Mar 01. Date of Electronic Publication: 2024 Mar 01.