Zobrazeno 1 - 10
of 845
pro vyhledávání: '"Mochel, P."'
Non-small cell lung cancer (NSCLC) is often intrinsically resistant to several first- and second-line therapeutics and can rapidly acquire further resistance after a patient begins receiving treatment. Treatment outcomes are therefore significantly i
Externí odkaz:
http://arxiv.org/abs/2410.16967
Autor:
Jonathan P. Mochel, Jessica L. Ward, Thomas Blondel, Debosmita Kundu, Maria M. Merodio, Claudine Zemirline, Emilie Guillot, Ryland T. Giebelhaus, Paulina de la Mata, Chelsea A. Iennarella-Servantez, April Blong, Seo Lin Nam, James J. Harynuk, Jan Suchodolski, Asta Tvarijonaviciute, José Joaquín Cerón, Agnes Bourgois-Mochel, Faiez Zannad, Naveed Sattar, Karin Allenspach
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Cardiovascular-kidney-metabolic health reflects the interactions between metabolic risk factors, chronic kidney disease, and the cardiovascular system. A growing body of literature suggests that metabolic syndrome (MetS) in individuals of no
Externí odkaz:
https://doaj.org/article/d64609278e0c44a5a0b47e66b29defbd
Autor:
Ryan Flynn, Haley Cremerius, Lisa Ebner, Pierre-Yves Mulon, Jessica Garcia, Kailee Bennett, Jessica Gerbert, Lainey Harvill, Olivia Escher, Channing Cantrell, Windy Soto-Gonzalez, Rebecca R. Rahn, Jeff D. Olivarez, Lingnan Yuan, Jonathan P. Mochel, Amanda J. Kreuder, Joe Smith
Publikováno v:
Ruminants, Vol 4, Iss 3, Pp 304-315 (2024)
(1) Background: Multiple point-of-care (POC) glucometers are in use in veterinary medicine, but few are compared to each other. This leaves the potential for clinicians to be unaware of the effect of bias when comparing results from different POC glu
Externí odkaz:
https://doaj.org/article/030e8788c3a94e2c90e34f57a60eca8b
Autor:
Tatiana M. Garcia Marrero, Jessica L. Ward, Melissa A. Tropf, Agnes Bourgois‐Mochel, Emilie Guillot, Oliver Domenig, Lingnan Yuan, Debosmita Kundu, Jonathan P. Mochel
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 2, Pp 913-921 (2024)
Abstract Background Systemic hypertension (SH) is a common cardiovascular disease in older cats that is treated primarily with the calcium channel blocker amlodipine besylate (AML). The systemic effect of AML on the classical and alterative arms of t
Externí odkaz:
https://doaj.org/article/88b262a8e2244c0f96cbe165d0951d70
Autor:
Adam T. Copeland, Amanda J. Kreuder, Grant Dewell, Renee Dewell, Caitlin Wiley, Lingnan Yuan, Jonathan P. Mochel, Joe S. Smith
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 3, Pp 1941-1950 (2024)
Abstract Background Hypothermia is a cause of neonatal calf death in cold climates. Practical and effective rewarming methods are important for bovine health within affected regions. Hypothesis/Objectives To compare the rewarming rate and blood analy
Externí odkaz:
https://doaj.org/article/30ca8b699df047c8a6652d019e3a6117
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
We introduce a novel tree-based method for visualizing molecular conformation sampling. Our method offers enhanced precision in highlighting conformational differences and facilitates the observation of local minimas within proteins fold space. The p
Externí odkaz:
https://doaj.org/article/0bb247047bb5414282eab07cef68e480
Autor:
Karin Allenspach, Andreas Handel, Stanley Marks, Peter Kook, Kenny Simpson, Joseph Bartges, Kenjiro Fukushima, Aarti Kathrani, Silke Salavati, Julien Dandrieux, Caroline Mansfield, Alison Manchester, Craig Webb, Valerie Freiche, W. Zane Billings, Jonathan P. Mochel
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 3, Pp 1282-1284 (2024)
Externí odkaz:
https://doaj.org/article/6bae9d9ad35645258e859d61852422a7
Autor:
Christopher Zdyrski, Vojtech Gabriel, Thea B. Gessler, Abigail Ralston, Itzel Sifuentes-Romero, Debosmita Kundu, Sydney Honold, Hannah Wickham, Nicholas E. Topping, Dipak Kumar Sahoo, Basanta Bista, Jeffrey Tamplin, Oscar Ospina, Pablo Piñeyro, Marco Arriaga, Jacob A. Galan, David K. Meyerholz, Karin Allenspach, Jonathan P. Mochel, Nicole Valenzuela
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-19 (2024)
Abstract Painted turtles are remarkable for their freeze tolerance and supercooling ability along with their associated resilience to hypoxia/anoxia and oxidative stress, rendering them an ideal biomedical model for hypoxia-induced injuries (includin
Externí odkaz:
https://doaj.org/article/531fb488b91342cbb3698ef755cb2111
Autor:
Daphne H. Schoenmakers, Fanny Mochel, Laura A. Adang, Jaap-Jan Boelens, Valeria Calbi, Erik A. Eklund, Sabine W. Grønborg, Francesca Fumagalli, Samuel Groeschel, Caroline Lindemans, Caroline Sevin, Ludger Schöls, Dipak Ram, Ayelet Zerem, Holm Graessner, Nicole I. Wolf
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background For decades, early allogeneic stem cell transplantation (HSCT) has been used to slow neurological decline in metachromatic leukodystrophy (MLD). There is lack of consensus regarding who may benefit, and guidelines are lacking. Cli
Externí odkaz:
https://doaj.org/article/15b67733f9df4ad2852654ef151aeadb
Autor:
Huin, Vincent, Coarelli, Giulia, Guemy, Clément, Boluda, Susana, Debs, Rabab, Mochel, Fanny, Stojkovic, Tanya, Grabli, David, Maisonobe, Thierry, Gaymard, Bertrand, Lenglet, Timothée, Tard, Céline, Davion, Jean-Baptiste, Sablonnière, Bernard, Monin, Marie-Lorraine, Ewenczyk, Claire, Viala, Karine, Charles, Perrine, Ber, Isabelle Le, Reilly, Mary, Houlden, Henry, Cortese, Andrea, Seilhean, Danielle, Brice, Alexis, Durr, Alexandra
Publikováno v:
Brain - A Journal of Neurology , Oxford University Press (OUP), 2021
CANVAS caused by RFC1 biallelic expansions is a major cause of inherited sensory neuronopathy. Detection of RFC1 expansion is challenging and CANVAS can be associated with atypical features. We clinically and genetically characterized 50 patients, se
Externí odkaz:
http://arxiv.org/abs/2201.10143