Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia

Autor: Polychronidou, Eleftheria, Kalamaras, Ilias, Agathangelidis, Andreas, Sutton, Lesley Ann, Yan, Xiao Jie, Bikos, Vasilis, Vardi, Anna, Mochament, Konstantinos, Chiorazzi, Nicholas, Belessi, Chrysoula, Rosenquist, Richard, Ghia, Paolo, Stamatopoulos, Kostas, Vlamos, Panayiotis, Chailyan, Anna, Overby, Nanna, Marcatili, Paolo, Hatzidimitriou, Anastasia, Tzovaras, Dimitrios

Publikováno v: Polychronidou, E, Kalamaras, I, Agathangelidis, A, Sutton, L A, Yan, X J, Bikos, V, Vardi, A, Mochament, K, Chiorazzi, N, Belessi, C, Rosenquist, R, Ghia, P, Stamatopoulos, K, Vlamos, P, Chailyan, A, Overby, N, Marcatili, P, Hatzidimitriou, A & Tzovaras, D 2018, ' Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia ', BMC Bioinformatics, vol. 19, no. Suppl. 14, 414 . https://doi.org/10.1186/s12859-018-2381-1

Background: Although the etiology of chronic lymphocytic leukemia (CLL), the most common type of adult leukemia, is still unclear, strong evidence implicates antigen involvement in disease ontogeny and evolution. Primary and 3D structure analysis has

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