Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mobin A. Tawakkul"'
Publikováno v:
Pharmacology & Pharmacy. :281-290
The mechanism of degradation of dantrolene in aqueous buffer solutions was studied at various pH values in the range of pH 1.2-9.5 and at temperatures ranging from 25℃ to 75℃ to determine the optimum pH and temperature requirements for its stabil
Publikováno v:
Clinical Research and Regulatory Affairs. 27:21-29
A rapid, sensitive, and specific ultra-performance liquid chromatographic (UPLC) method was developed for the simultaneous determination of dantrolene and its potential degradation impurities. Chro...
Publikováno v:
Drug Development and Industrial Pharmacy. 35:1409-1418
The purpose of this work was to investigate the effect of preparation methods and the drug-to-resin ratio on complex formation between risperidone and amberlite resin.The existence of such resin complex may provide taste-masking properties to the dos
Publikováno v:
Pharmaceutical Development and Technology. 14:409-421
The purpose of the study was to investigate the complexation between a weakly basic drug (risperidone) and an ion exchange resin (amberlite IRP-64) used as a taste-masking agent via two preparation methods: physical mixture and solvent evaporation. B
Publikováno v:
AAPS PharmSciTech. 10:500-504
The purpose of this work was to evaluate and compare the functionality of bovine fatty acids-derived (MgSt-B) and vegetable fatty acids-derived (MgSt-V) magnesium stearate powders when used for the lubrication of granules prepared by high-shear (HSG)
Publikováno v:
AAPS PharmSciTech. 9:250-258
The objective of the present work was to carry out a systematic evaluation of flow of pharmaceutical powders and granules using compendial and non-compendial methods. Angle of repose, bulk density, tapped density, Carr's compressibility index, and Ha
Publikováno v:
International Journal of Pharmaceutics. 341:189-194
In the present work, a novel application of ultrasonic measurements is detailed to characterize nano-emulsion formulations as a part of the overall Quality by Design (QbD) goal. Ultrasonic resonator technology (URT) was utilized to measure sound velo
Autor:
Donna A. Volpe, Hyojong Kwon, Ebenezer B. Asafu-Adjaye, Mobin A. Tawakkul, Lawrence W. Anderson, Patrick J. Faustino, Lawrence X. Yu
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 43:1854-1859
Gastrointestinal stability of venlafaxine was evaluated in vitro in simulated gastric (SGF) and intestinal (SIF) fluids using a stability indicating HPLC method. The method was validated using a 5 microm Ascentis C18 column (150 mm x 4.6 mm) and mobi
Autor:
Mansoor A. Khan, Mobin A. Tawakkul, Patrick J. Faustino, Prasanna R. Hullahalli, Rakhi B. Shah, Agnes Nguyenpho
Publikováno v:
Clinical Research and Regulatory Affairs. 23:35-51
An isocratic reversed-phase high-performance liquid chromatographic method was developed and validated for the determination of ranitidine HCl in syrup. The samples were analyzed by high-performanc...
Publikováno v:
International journal of pharmaceutics. 401(1-2)
Metoprolol succinate extended release tablets comprise a multiple unit system containing metoprolol succinate in a multitude of controlled release pellets. Each pellet acts as a separate drug delivery unit and is designed to deliver metoprolol contin