Zobrazeno 1 - 10
of 833
pro vyhledávání: '"Mobile element"'
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 38, Iss , Pp 227-230 (2024)
Objectives: To investigate the tet(X) gene, a determinant of tigecycline resistance, in the emerging pathogen Elizabethkingia meningoseptica and its association with an integrative and conjugative element (ICE). Methods: All E. meningoseptica genomes
Externí odkaz:
https://doaj.org/article/7300e0e2464749c58d0f84f3d5194413
Autor:
Xin-Yan Fan, Yue Jiang, Han Wu, Jie Liu, Qing-Yun Gu, Zhen-Yu Wang, Lin Sun, Xinan Jiao, Qiuchun Li, Jing Wang
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Tigecycline serves as a last-resort antimicrobial agent against severe infections caused by multidrug-resistant bacteria. Tet(X) and its numerous variants encoding flavin-dependent monooxygenase can confer resistance to tigecycline, with tet(X4) bein
Externí odkaz:
https://doaj.org/article/57c669fa54ef4084a171dc9da86bcdbd
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 12, Iss 3, Pp n/a-n/a (2024)
Abstract Background Familial hypercholesterolemia (MIM: PS143890) is a genetic disorder characterized by an increase in blood cholesterol. LDLR is one of the genes which their defect contributes to the disorder. Affected individuals may carry a heter
Externí odkaz:
https://doaj.org/article/6a7477e0eda544abb134fe80cbc0d97a
Akademický článek
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SCIFER: approach for analysis of LINE-1 mRNA expression in single cells at a single locus resolution
Autor:
Emily C. Stow, Melody Baddoo, Alexis J. LaRosa, Dawn LaCoste, Prescott Deininger, Victoria Belancio
Publikováno v:
Mobile DNA, Vol 13, Iss 1, Pp 1-20 (2022)
Abstract Background Endogenous expression of L1 mRNA is the first step in an L1-initiated mutagenesis event. However, the contribution of individual cell types to patterns of organ-specific L1 mRNA expression remains poorly understood, especially at
Externí odkaz:
https://doaj.org/article/eb7e2933ba034fd3a88cf17d82998512
Autor:
Gérard Guédon, Julie Lao, Sophie Payot, Thomas Lacroix, Hélène Chiapello, Nathalie Leblond-Bourget
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-4 (2022)
Abstract Objectives ‘Integrative and Conjugative Elements’ (ICEs) and ‘Integrative and Mobilizable Elements’ (IMEs) are two classes of mobile genetic elements that are complex to detect and delineate. Therefore, they are yet poorly annotated
Externí odkaz:
https://doaj.org/article/bb7c1376fea743e7bbdf5e6e5c73587b
Autor:
François P. Douillard, Inês Martins Portinha, Yağmur Derman, Cédric Woudstra, Tommi Mäklin, Martin B. Dorner, Hannu Korkeala, Adriano O. Henriques, Miia Lindström
Publikováno v:
Viruses, Vol 15, Iss 12, p 2431 (2023)
Sporulation is a finely regulated morphogenetic program important in the ecology and epidemiology of Clostridium botulinum. Exogenous elements disrupting sporulation-associated genes contribute to sporulation regulation and introduce diversity in the
Externí odkaz:
https://doaj.org/article/561ef2e3f4704224b01857a3548a23f1
Autor:
Chunyang Wu, Ying Zhou, Wenxiu Ai, Yinjuan Guo, Xiaocui Wu, Bingjie Wang, Huilin Zhao, Lulin Rao, Xinyi Wang, Jiao Zhang, Fangyou Yu, Liangxing Wang
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) strains and restricted therapeutic options pose a global threat to public health. Aminoglycosides are a wise choice, which can effectively reduce the mortality rate when combined with
Externí odkaz:
https://doaj.org/article/d6aee57259644089a42d18ac2bd49e48
Autor:
Matias I. Autio, Talal Bin Amin, Arnaud Perrin, Jen Yi Wong, Roger S.-Y. Foo, Shyam Prabhakar
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-17 (2021)
Abstract Background Transposable elements (TE) comprise nearly half of the human genome and their insertions have profound effects to human genetic diversification and as well as disease. Despite their abovementioned significance, there is no consens
Externí odkaz:
https://doaj.org/article/37cbd73da4dc4bac9f79b35ef2968e33
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Free-living bacteria have evolved multiple times to become host-restricted endosymbionts. The transition from a free-living to a host-restricted lifestyle comes with a number of different genomic changes, including a massive loss of genes. I
Externí odkaz:
https://doaj.org/article/29bd0665dc0c4c7896f8308720482c51