Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Mobien Kasiem"'
Autor:
Lyle E. Pegg, Jens Hausmann, Harald M. H. G. Albers, Leonie van Zeijl, Karl Harlos, Wouter H. Moolenaar, Susan S. Smyth, Evangelos Christodoulou, Jacqueline E. Day, Craig W. Vander Kooi, Mobien Kasiem, Andrew J. Morris, Timothy E. Benson, Anna J. S. Houben, Anastassis Perrakis, Maria Andries, Zachary Fulkerson, Mathieu Bollen, Tao Wu, Silvia Jansen, Satwik Kamtekar, Troii Hall, Laurens A. van Meeteren, Huib Ovaa
Publikováno v:
Nature Structural & Molecular Biology. 18:198-204
Autotaxin (ATX, also known as ectonucleotide pyrophosphatase/phosphodiesterase-2, ENPP2) is a secreted lysophospholipase D that generates the lipid mediator lysophosphatidic acid (LPA), a mitogen and chemoattractant for many cell types. ATX-LPA signa
Autor:
Evangelos Christodoulou, Valeria De Marco, Mobien Kasiem, Robin L. Owen, Laurens A. van Meeteren, Jens Hausmann, Gwyndaf Evans, Wouter H. Moolenaar, Danny Axford, Anastassis Perrakis
Publikováno v:
Acta Crystallographica Section F: Structural Biology and Crystallization Communications
Autotaxin, a four-domain ∼100 kDa mammalian glycoprotein, was expressed in stably transfected mammalian cells, purified from the medium and crystallized. Diffraction data from micrometre-thick crystal plates were collected on various European synch