Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico

Autor: Mobarak, Edouard, Håversen, Liliana, Manna, Moutusi, Rutberg, Mikael, Levin, Malin, Perkins, Rosie, Rog, Tomasz, Vattulainen, Ilpo, Borén, Jan

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Mobarak, E, Håversen, L, Manna, M, Rutberg, M, Levin, M, Perkins, R, Rog, T, Vattulainen, I & Borén, J 2018, ' Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico ', Scientific Reports, vol. 8, 13600 . https://doi.org/10.1038/s41598-018-31926-0
Scientific Reports

Toll-like receptor 4 (TLR4) is activated by bacterial lipopolysaccharide (LPS), which drives the production of proinflammatory cytokines. Earlier studies have indicated that cholesterol- and glycosphingolipid-rich subregions of the plasma membrane (l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3f85c8056ef505ffd3f23c7dc2012aba
http://link.springer.com/article/10.1038/s41598-018-31926-0

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