Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Moaddey Alfarhan"'
Autor:
Fang Liu, Moaddey Alfarhan, Leanna Baker, Nidhi Shenoy, Yini Liao, Harry O. Henry-Ojo, Payaningal R. Somanath, S. Priya Narayanan
Publikováno v:
Cells, Vol 11, Iss 24, p 4100 (2022)
Multiple Sclerosis (MS) is a highly disabling neurological disease characterized by inflammation, neuronal damage, and demyelination. Vision impairment is one of the major clinical features of MS. Previous studies from our lab have shown that MDL 725
Externí odkaz:
https://doaj.org/article/01a4df9a535c4b0b9d2eecdddd2a96b0
Autor:
Amritha A Candadai, Fang Liu, Abdelrahman Y Fouda, Moaddey Alfarhan, Chithra D Palani, Zhimin Xu, Ruth B Caldwell, S Priya Narayanan
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247901 (2021)
Vision impairment due to optic neuritis (ON) is one of the major clinical presentations in Multiple Sclerosis (MS) and is characterized by inflammation and degeneration of the optic nerve and retina. Currently available treatments are only partially
Externí odkaz:
https://doaj.org/article/274aeb5ae28b4b918a2679c336cb5cd5
Autor:
Moaddey Alfarhan, Fang Liu, Shengshuai Shan, Prahalathan Pichavaram, Payaningal R. Somanath, S. Priya Narayanan
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2133 (2022)
Polyamine oxidation plays a major role in neurodegenerative diseases. Previous studies from our laboratory demonstrated that spermine oxidase (SMOX, a member of the polyamine oxidase family) inhibition using MDL 72527 reduced neurodegeneration in mod
Externí odkaz:
https://doaj.org/article/e1d7d64ebd25412f9c2d1b11d9d415ef
Autor:
Amritha A. Candadai, Fang Liu, Arti Verma, Mir S. Adil, Moaddey Alfarhan, Susan C. Fagan, Payaningal R. Somanath, S. Priya Narayanan
Publikováno v:
Cells, Vol 10, Iss 11, p 2938 (2021)
Visual dysfunction resulting from optic neuritis (ON) is one of the most common clinical manifestations of multiple sclerosis (MS), characterized by loss of retinal ganglion cells, thinning of the nerve fiber layer, and inflammation to the optic nerv
Externí odkaz:
https://doaj.org/article/84d2577ff1f94fce89aef8faa6029b1e
Publikováno v:
Biomolecules, Vol 10, Iss 11, p 1579 (2020)
Diabetic retinopathy (DR) is the leading cause of vision loss among working-age adults. Extensive evidences have documented that oxidative stress mediates a critical role in the pathogenesis of DR. Acrolein, a product of polyamines oxidation and lipi
Externí odkaz:
https://doaj.org/article/fec55b154e234eafafe79eb2d880fcb0
Autor:
Chithra D. Palani, Ruth B. Caldwell, Moaddey Alfarhan, Abdelrahman Y. Fouda, S. Priya Narayanan, Amritha A. Candadai, Fang Liu, Zhimin Xu
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247901 (2021)
PLoS ONE
PLoS ONE
Vision impairment due to optic neuritis (ON) is one of the major clinical presentations in Multiple Sclerosis (MS) and is characterized by inflammation and degeneration of the optic nerve and retina. Currently available treatments are only partially
Autor:
Susan C. Fagan, Arti Verma, Fang Liu, S. Priya Narayanan, Mir S Adil, Payaningal R. Somanath, Amritha A. Candadai, Moaddey Alfarhan
Publikováno v:
Cells
Volume 10
Issue 11
Cells, Vol 10, Iss 2938, p 2938 (2021)
Volume 10
Issue 11
Cells, Vol 10, Iss 2938, p 2938 (2021)
Visual dysfunction resulting from optic neuritis (ON) is one of the most common clinical manifestations of multiple sclerosis (MS), characterized by loss of retinal ganglion cells, thinning of the nerve fiber layer, and inflammation to the optic nerv
Publikováno v:
Biomolecules
Biomolecules, Vol 10, Iss 1579, p 1579 (2020)
Biomolecules, Vol 10, Iss 1579, p 1579 (2020)
Diabetic retinopathy (DR) is the leading cause of vision loss among working-age adults. Extensive evidences have documented that oxidative stress mediates a critical role in the pathogenesis of DR. Acrolein, a product of polyamines oxidation and lipi