Zobrazeno 1 - 2
of 2
pro vyhledávání: '"MoPrP, mouse PrP"'
Autor:
Gerold Schmitt-Ulms, Mohadeseh Mehrabian, Hamza Arshad, Joel C. Watts, Zaid A.M. Al-Azzawi, Matthew E. C. Bourkas, Zeel Patel
Publikováno v:
The Journal of Biological Chemistry
The study of prions and the discovery of candidate therapeutics for prion disease have been facilitated by the ability of prions to replicate in cultured cells. Paradigms in which prion proteins from different species are expressed in cells with low
Autor:
Elena Quaglio, Vanessa Capone, Vladimiro Artuso, Fabio Fiordaliso, Ignazio Roiter, Davide Ortolan, Michele Sallese, Alessandro Corbelli, Galina V. Beznoussenko, Elena Restelli, Manuela Pozzoli, Roberto Chiesa
Publikováno v:
The Journal of Biological Chemistry
Fatal familial insomnia (FFI), genetic Creutzfeldt–Jakob disease (gCJD), and Gerstmann–Sträussler–Scheinker (GSS) syndrome are neurodegenerative disorders linked to prion protein (PrP) mutations. The pathogenic mechanisms are not known, but in