Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Mo-fei Li"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In the complement system, C3 is a central component in complement activation, immune defense and immune regulation. In all pathways of complement activation, the pivotal step is conversion of the component C3 to C3b and C3a, which is responsible to e
Externí odkaz:
https://doaj.org/article/fecb5092db7e45c392d90ca895547f89
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Translocation and assembly module (TAM) is a protein channel known to mediate the secretion of virulence factors during pathogen infection. Edwardsiella tarda is a Gram-negative bacterium that is pathogenic to a wide range of farmed fish and other ho
Externí odkaz:
https://doaj.org/article/9457e020937b4f1c877db1b5229ef199
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Edwardsiella tarda is a broad-host pathogen that can infect mammals, reptiles, and fish. E. tarda exhibits a remarkable ability to survive in host serum and replicate in host phagocytes, but the underlining mechanism is unclear. In this study, in ord
Externí odkaz:
https://doaj.org/article/fe8d8cbc51804bed86602912010bed26
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106543 (2014)
NK-lysin is an antimicrobial protein produced by cytotoxic T lymphocytes and natural killer cells. In this study, we examined the biological property of a peptide, NKLP27, derived from tongue sole (Cynoglossus semilaevis) NK-lysin. NKLP27 is composed
Externí odkaz:
https://doaj.org/article/17db47a798794c929700177dc0cef0d0
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e96222 (2014)
Streptococcus iniae is a Gram-positive bacterium and a severe pathogen to a wide range of economically important fish species. In addition, S. iniae is also a zoonotic pathogen and can cause serious infections in humans. In this study, we identified
Externí odkaz:
https://doaj.org/article/2dba459fa5d2471fa0f9fd6073de3022
Publikováno v:
Fish & Shellfish Immunology. 104:439-446
In this study, we examined the function of a Japanese flounder (Paralichthys olivaceus) microRNA (miRNA), pol-miR-363-3p. We found that pol-miR-363-3p targets an ubiquitin-specific protease (USP), USP32. USP is a family of deubiquitinating enzymes es
Publikováno v:
Fish & Shellfish Immunology. 97:18-26
In mammals, complement factor I (CFI) is a serine protease in serum and plays a pivotal role in the regulation of complement activation. In the presence of cofactor, CFI cleaves C3b to iC3b, and further degrades iC3b to C3c and C3d. In teleost, the f
Publikováno v:
Aquaculture. 567:739289
Publikováno v:
Fish & Shellfish Immunology. 132:108472
Complement C1q domain containing protein (C1qDC) is a vital recognition molecule and has an important effect on immunity. The C1qDCs exhibit opsonic activity in fish, while the mechanisms of C1qDCs in activation complement still remain unclear. This
Autor:
Mo-Fei, Li, Hong-Qiang, Zhang
Publikováno v:
Developmental & Comparative Immunology. 137:104520
Complement plays an important role in the innate immune system, and it comprises about 35 individual proteins. In mammals, complement is activated via three different pathways, the classical pathway, the alternative pathway, and the lectin pathway. A