Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Mo Jun Lin"'
Autor:
Rui-Xing Wang, Rui-Lan He, Hai-Xia Jiao, Run-Tian Zhang, Jing-Yi Guo, Xiao-Ru Liu, Long-Xin Gui, Mo-Jun Lin, Zhi-Juan Wu
Publikováno v:
Pharmaceutical Biology, Vol 58, Iss 1, Pp 1055-1063 (2020)
Context Ginsenoside Rb1, the main active ingredient of ginseng, exhibits ex vivo depression of store-operated calcium entry (SOCE) and related vasoconstriction in pulmonary arteries derived from pulmonary hypertension (PH) rats. However, the in vivo
Externí odkaz:
https://doaj.org/article/903f3d8974614ea5918d59a448d58d8d
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-20 (2019)
Abstract Background Pulmonary artery hypertension (PAH), which is characterized by an increase in pulmonary circulation blood pressure, is a fatal disease, and its pathogenesis remains unclear. Methods In this study, RNA sequencing (RNA-seq), tandem
Externí odkaz:
https://doaj.org/article/53b6b6d6b3e64f518cdd99b57f34bde2
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 2, Pp 763-777 (2018)
Background/Aims: Vascular muscularity is a key event in vessel remodeling during pulmonary artery hypertension (PAH). Endothelial-mesenchymal transdifferentiation (EndMT) has been increasingly reported to play a role in disease occurrence. Galectin-3
Externí odkaz:
https://doaj.org/article/a5ae8ba9c8dc448498f80eef06cd9d61
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 1, Pp 172-189 (2018)
Background/Aims: Pulmonary arterial hypertension (PAH) is a severe and debilitating disease characterized by remodeling of the pulmonary vessels, which is driven by excessive proliferation and migration and apoptosis resistance in pulmonary artery sm
Externí odkaz:
https://doaj.org/article/1d52a1189da04517972d0a139ae5a23e
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 2, Pp 438-452 (2016)
Background/Aims: Alterations in intracellular Ca2+ concentration ([Ca2+]i) underlie the pathogenesis of various cardiovascular diseases. Caveolin-1 (Cav-1) is the primary functional protein associated with caveolae, which are invaginations in the pla
Externí odkaz:
https://doaj.org/article/4ea8b3dd797d42a1ab5f69785e8a66e8
Autor:
Da Cen Lin, Rui Xiang Zhou, Li Li, Zhuang Li Zhu, Jian-Hua Luo, Si Yi Zheng, Zhi Guang Zhang, Mo Jun Lin, Xinjian Lin, Lu Shan Chen, James S.K. Sham
Publikováno v:
Cancer Letters. 519:211-225
The transient receptor potential canonical (TRPC) channels have been implicated in various types of malignancies including gastric cancer (GC). However, the detailed mechanisms of TRPC channels underlying cell proliferation and apoptosis of GC cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2005817070536ecff2fbe8ca67ddc966
https://doi.org/10.1016/j.canlet.2021.07.038
https://doi.org/10.1016/j.canlet.2021.07.038
Autor:
Zhi-Juan Wu, Jing Yu, Qiu-Juan Fang, Rui-Xing Wang, Jia-Bian Lian, Rui-Lan He, Hai-Xia Jiao, Mo-Jun Lin
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 6, Pp 2121-2136 (2015)
Background: Daunorubicin (DNR)-induced cardiotoxicity, which is closely associated with cardiomyocyte apoptosis, limits the drug's clinical application. The activation of the extracellular regulated protein kinases (ERKs) pathway is responsible for t
Externí odkaz:
https://doaj.org/article/0f1ab91002e54ae69fcb93ccaab53a97
Autor:
Rui-Xing Wang, Rui-Lan He, Hai-Xia Jiao, Mao Dai, Yun-Ping Mu, Ying Hu, Zhi-Juan Wu, James S.K. Sham, Mo-Jun Lin
Publikováno v:
Cellular Physiology and Biochemistry, Vol 35, Iss 4, Pp 1467-1481 (2015)
Background: Pulmonary hypertension (PH) is characterized by sustained vasoconstriction, enhanced vasoreactivity and vascular remodeling, which leads to right heart failure and death. Despite several treatments are available, many forms of PH are stil
Externí odkaz:
https://doaj.org/article/36ca4a90697f4cf09b6dd1e3d85ab5d1
Publikováno v:
Journal of hypertension. 40(10)
Vascular calcification has been considered as a potential therapeutic target in pulmonary hypertension. Mg2+ has a protective role against calcification. This study aimed to investigate whether Mg2+ could alleviate pulmonary hypertension by reducing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d9b7d5f4795f334fddad3721efeaad
https://pubmed.ncbi.nlm.nih.gov/36052522
https://pubmed.ncbi.nlm.nih.gov/36052522
Autor:
Gui-Feng Lu, Fei Geng, Li-Ping Deng, Da-Cen Lin, Yan-Zhen Huang, Su-Mei Lai, Yi-Chen Lin, Long-Xin Gui, James S.K. Sham, Mo-Jun Lin
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 79(11)
Background: Pulmonary arterial hypertension maintains rapid cell proliferation and vascular remodeling through metabolic reprogramming. Recent studies suggested that circRNAs play important role in pulmonary vascular remodeling and pulmonary arterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df3af293db10590feb1e5f25b52dc2c
https://pubmed.ncbi.nlm.nih.gov/35997022
https://pubmed.ncbi.nlm.nih.gov/35997022