Zobrazeno 1 - 10 of 158 pro vyhledávání: '"Mn porphyrins"'
1
Akademický článek
The central role of NADPH depletion in MnTE-2-PyP-induced prostate cancer cell growth inhibition
Autor: Yuxiang Zhu, Divya Murthy, Sai Sundeep Kollala, Elizabeth A. Kosmacek, Arpita Chatterjee, Joshua A. McDowell, Pankaj K. Singh, Rebecca E. Oberley-Deegan
Publikováno v: Advances in Redox Research, Vol 3, Iss , Pp 100025- (2021)
Radiotherapy is commonly used in prostate cancer treatment. MnTE-2-PyP is a superoxide dismutase (SOD) mimic that can protect normal tissues from radiation toxicities while simultaneously promoting radiation-induced damage to cancer tissues. Previous
Externí odkaz: https://doaj.org/article/c88a430211594c2db68f4a6a08566a9f
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2
Akademický článek
Effects of Manganese Porphyrins on Cellular Sulfur Metabolism
Autor: Kenneth R. Olson, Yan Gao, Andrea K. Steiger, Michael D. Pluth, Charles R. Tessier, Troy A. Markel, David Boone, Robert V. Stahelin, Ines Batinic-Haberle, Karl D. Straubg
Publikováno v: Molecules, Vol 25, Iss 4, p 980 (2020)
Manganese porphyrins (MnPs), MnTE-2-PyP5+, MnTnHex-2-PyP5+ and MnTnBuOE-2-PyP5+, are superoxide dismutase (SOD) mimetics and form a redox cycle between O2 and reductants, including ascorbic acid, ultimately producing hydrogen peroxide (H2O2). We prev
Externí odkaz: https://doaj.org/article/175883133928472f8a1e4bd315c8543f
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3
Ascorbate-dependent and ascorbate-independent Mn porphyrin cytotoxicity: anticancer activity of Mn porphyrin-based SOD mimics through ascorbate-dependent and -independent routes
Autor: Bader Hasan, Ines Batinic-Haberle, Artak Tovmasyan, Ludmil Benov
Publikováno v: Redox Report, Vol 26, Iss 1, Pp 85-93 (2021)
Redox Report : Communications in Free Radical Research
article-version (VoR) Version of Record
Objective The aim of this study was to investigate how modifications at the periphery of the porphyrin ring affect the anticancer activity of Mn porphyrins (MnPs)-based SOD mimics. Methods Six compounds: MnTE-2-PyP with a short ethyl chain on the pyr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40200af374a0a130d31ba69c85bb5d0
https://doi.org/10.1080/13510002.2021.1917214
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4
Akademický článek
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5
The central role of NADPH depletion in MnTE-2-PyP-induced prostate cancer cell growth inhibition
Autor: Pankaj K. Singh, Yuxiang Zhu, Sai Sundeep Kollala, Divya Murthy, Arpita Chatterjee, Elizabeth A. Kosmacek, Rebecca E. Oberley-Deegan, Joshua A. McDowell
Publikováno v: Advances in Redox Research, Vol 3, Iss, Pp 100025-(2021)
Radiotherapy is commonly used in prostate cancer treatment. MnTE-2-PyP is a superoxide dismutase (SOD) mimic that can protect normal tissues from radiation toxicities while simultaneously promoting radiation-induced damage to cancer tissues. Previous
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a111f159ba6e9ae6bc8f78cae09d08
http://www.sciencedirect.com/science/article/pii/S2667137921000254
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6
Desenvolvimento de mímicos das enzimas superóxido dismutases (SOD) e fotossensibilizadores à base de metaloporfirinas hidrossolúveis do tipo [A3B]3+ ou [A4] 4+ (A = 2-N-alquilpiridínio; B = vanilina ou O-alquilvanilina)
Autor: Sarmento Neto, José Ferreira
Publikováno v: Biblioteca Digital de Teses e Dissertações da UFPB
Universidade Federal da Paraíba (UFPB)
instacron:UFPB
Water-soluble Mn(III)-porphyrins and Zn(II)-porphyrins (MnPs ou ZnPs) derived from 2-N-alkylpyridiniumporphyrins, MnTalkyl-2-PyP5+ or ZnTalkyl-2-PyP4+, have been widely explored as redox-active therapeutics or photosensitizers (PSs). The in vivo effi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::ebf70de9f0def60b6ca7406d2699d74e
https://repositorio.ufpb.br/jspui/handle/123456789/22774
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7
Ortho Isomeric Mn(III) N-Alkyl- and Alkoxyalkylpyridylporphyrins—Enhancers of Hyaluronan Degradation Induced by Ascorbate and Cupric Ions
Autor: Ladislav Šoltés, Katarína Valachová, Ines Batinic-Haberle, Nuno M. M. Moura, Peter Rapta
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 8608, p 8608 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16
High levels of hyaluronic acid (HA) in tumors correlate with poor outcomes with several types of cancers due to HA-driven support of adhesion, migration and proliferation of cells. In this study we explored how to enhance the degradation of HA into l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cc3b5531cddba5ff074abefacf36ed
https://www.mdpi.com/1422-0067/22/16/8608
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8
25 years of development of Mn porphyrins — from mimics of superoxide dismutase enzymes to thiol signaling to clinical trials: The story of our life in the USA
Autor: Ivan Spasojevic, Ines Batinic-Haberle
Publikováno v: Journal of Porphyrins and Phthalocyanines. 23:1326-1335
We have developed Mn porphyrins (MnPs) initially as mimics of superoxide dismutase (SOD) enzymes based on structure–activity relationships. Several cationic Mn porphyrins, being substituted with cationic ortho [Formula: see text]-alkyl- or alkoxyal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b90f65c5031c8a632b9f3ce497fd879b
https://doi.org/10.1142/s1088424619300283
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9
Akademický článek
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10
Akademický článek
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