Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Mlcochova, Petra"'
Autor:
Mlčochová, Petra
CONCLUSIONS AND PERSPECTIVES Recentry reported crystal sructures of GCpII provide stucturar insight into the organization of the substrate binding cavity and highlight residues implicated in substrate / inhibitor binding in the sI site of the enzyme.
Externí odkaz:
http://www.nusl.cz/ntk/nusl-372398
Autor:
Meng, Bo, Zhao, Na, Mlcochova, Petra, Ferreira, Isabella A.T.M., Ortmann, Brian M., Davis, Tanja, Wit, Niek, Rehwinkel, Jan, Cook, Simon, Maxwell, Patrick H., Nathan, James A., Gupta, Ravindra K.
Publikováno v:
In Cell Reports 23 July 2024 43(7)
Autor:
Fernández, Jose Javier, Marín, Arturo, Rosales, Romel, Penrice-Randal, Rebekah, Mlcochova, Petra, Alvarez, Yolanda, Villalón-Letelier, Fernando, Yildiz, Soner, Pérez, Enrique, Rathnasinghe, Raveen, Cupic, Anastasija, Kehrer, Thomas, Uccellini, Melissa B., Alonso, Sara, Martínez, Fernando, McGovern, Briana Lynn, Clark, Jordan J., Sharma, Parul, Bayón, Yolanda, Alonso, Andrés, Albrecht, Randy A., White, Kris M., Schotsaert, Michael, Miorin, Lisa, Stewart, James P., Hiscox, Julian A., Gupta, Ravindra K., Irigoyen, Nerea, García-Sastre, Adolfo, Crespo, Mariano Sánchez, Fernández, Nieves
Publikováno v:
In BBA - Molecular Basis of Disease June 2024 1870(5)
Autor:
Gupta, Ravi K, Mlcochova, Petra
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents a great threat to human health. The interplay between the virus and host plays a crucial role in successful virus replication and transmission. Unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::7969f8c15f62aa3a29f8e4836bc935b6
https://www.repository.cam.ac.uk/handle/1810/341882
https://www.repository.cam.ac.uk/handle/1810/341882
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Mlcochova, Petra, Kemp, Steven A., Dhar, Mahesh Shanker, Papa, Guido, Meng, Bo, Ferreira, Isabella A. T. M., Datir, Rawlings, Collier, Dami A., Albecka, Anna, Singh, Sujeet, Pandey, Rajesh, Brown, Jonathan, Zhou, Jie, Goonawardane, Niluka, Mishra, Swapnil, Whittaker, Charles, Mellan, Thomas, Marwal, Robin, Datta, Meena, Sengupta, Shantanu, Ponnusamy, Kalaiarasan, Radhakrishnan, Venkatraman Srinivasan, Abdullahi, Adam, Charles, Oscar, Chattopadhyay, Partha, Devi, Priti, Caputo, Daniela, Peacock, Tom, Wattal, Chand, Goel, Neeraj, Satwik, Ambrish, Vaishya, Raju, Agarwal, Meenakshi, Chauhan, Himanshu, Dikid, Tanzin, Gogia, Hema, Lall, Hemlata, Verma, Kaptan, Singh, Manoj K., Soni, Namita, Meena, Namonarayan, Madan, Preeti, Singh, Priyanka, Sharma, Ramesh, Sharma, Rajeev, Kabra, Sandhya, Kumar, Sattender, Kumari, Swati, Sharma, Uma, Chaudhary, Urmila, Sivasubbu, Sridhar, Scaria, Vinod, Oberoi, J. K., Raveendran, Reena, Datta, S., Das, Saumitra, Maitra, Arindam, Chinnaswamy, Sreedhar, Biswas, Nidhan Kumar, Parida, Ajay, Raghav, Sunil K., Prasad, Punit, Sarin, Apurva, Mayor, Satyajit, Ramakrishnan, Uma, Palakodeti, Dasaradhi, Seshasayee, Aswin Sai Narain, Thangaraj, K., Bashyam, Murali Dharan, Dalal, Ashwin, Bhat, Manoj, Shouche, Yogesh, Pillai, Ajay, Abraham, Priya, Potdar, Varsha Atul, Cherian, Sarah S., Desai, Anita Sudhir, Pattabiraman, Chitra, Manjunatha, M. V., Mani, Reeta S., Udupi, Gautam Arunachal, Nandicoori, Vinay, Tallapaka, Karthik Bharadwaj, Sowpati, Divya Tej, Kawabata, Ryoko, Morizako, Nanami, Sadamasu, Kenji, Asakura, Hiroyuki, Nagashima, Mami, Yoshimura, Kazuhisa, Ito, Jumpei, Kimura, Izumi, Uriu, Keiya, Kosugi, Yusuke, Suganami, Mai, Oide, Akiko, Yokoyama, Miyabishara, Chiba, Mika, Saito, Akatsuki, Butlertanaka, Erika P., Tanaka, Yuri L., Ikeda, Terumasa, Motozono, Chihiro, Nasser, Hesham, Shimizu, Ryo, Yuan, Yue, Kitazato, Kazuko, Hasebe, Haruyo, Nakagawa, So, Wu, Jiaqi, Takahashi, Miyoko, Fukuhara, Takasuke, Shimizu, Kenta, Tsushima, Kana, Kubo, Haruko, Shirakawa, Kotaro, Kazuma, Yasuhiro, Nomura, Ryosuke, Horisawa, Yoshihito, Takaori-Kondo, Akifumi, Tokunaga, Kenzo, Ozono, Seiya, Baker, Stephen, Dougan, Gordon, Hess, Christoph, Kingston, Nathalie, Lehner, Paul J., Lyons, Paul A., Matheson, Nicholas J., Owehand, Willem H., Saunders, Caroline, Summers, Charlotte, Thaventhiran, James E. D., Toshner, Mark, Weekes, Michael P., Maxwell, Patrick, Shaw, Ashley, Bucke, Ashlea, Calder, Jo, Canna, Laura, Domingo, Jason, Elmer, Anne, Fuller, Stewart, Harris, Julie, Hewitt, Sarah, Kennet, Jane, Jose, Sherly, Kourampa, Jenny, Meadows, Anne, O'Brien, Criona, Price, Jane, Publico, Cherry, Rastall, Rebecca, Ribeiro, Carla, Rowlands, Jane, Ruffolo, Valentina, Tordesillas, Hugo, Bullman, Ben, Dunmore, Benjamin J., Fawke, Stuart, Graf, Stefan, Hodgson, Josh, Huang, Christopher, Hunter, Kelvin, Jones, Emma, Legchenko, Ekaterina, Matara, Cecilia, Martin, Jennifer, Mescia, Federica, O'Donnell, Ciara, Pointon, Linda, Pond, Nicole, Shih, Joy, Sutcliffe, Rachel, Tilly, Tobias, Treacy, Carmen, Tong, Zhen, Wood, Jennifer, Wylot, Marta, Bergamaschi, Laura, Betancourt, Ariana, Bower, Georgie, Cossetti, Chiara, De Sa, Aloka, Epping, Madeline, Gleadall, Nick, Grenfell, Richard, Hinch, Andrew, Huhn, Oisin, Jackson, Sarah, Jarvis, Isobel, Krishna, Ben, Lewis, Daniel, Marsden, Joe, Nice, Francesca, Okecha, Georgina, Omarjee, Ommar, Perera, Marianne, Potts, Martin, Richoz, Nathan, Romashova, Veronika, Yarkoni, Natalia Savinykh, Sharma, Rahul, Stefanucci, Luca, Stephens, Jonathan, Strezlecki, Mateusz, Turner, Lori, De Bie, Eckart M. D. D., Bunclark, Katherine, Josipovic, Masa, Mackay, Michael, Rossi, Sabrina, Selvan, Mayurun, Spencer, Sarah, Yong, Cissy, Allison, John, Butcher, Helen, Clapham-Riley, Debbie, Dewhurst, Eleanor, Furlong, Anita, Graves, Barbara, Gray, Jennifer, Ivers, Tasmin, Kasanicki, Mary, Le Gresley, Emma, Linger, Rachel, Meloy, Sarah, Muldoon, Francesca, Ovington, Nigel, Papadia, Sofia, Phelan, Isabel, Stark, Hannah, Stirrups, Kathleen E., Townsend, Paul, Walker, Neil, Webster, Jennifer, Scholtes, Ingrid, Hein, Sabine, King, Rebecca, Mavousian, Antranik, Lee, Joo Hyeon, Bassi, Jessica, Silacci-Fegni, Chiara, Saliba, Christian, Pinto, Dora, Irie, Takashi, Yoshida, Isao, Hamilton, William L., Sato, Kei, Bhatt, Samir, Flaxman, Seth, James, Leo C., Corti, Davide, Piccoli, Luca, Barclay, Wendy S., Rakshit, Partha, Agrawal, Anurag, Gupta, Ravindra K.
Publikováno v:
Mlcochova, P, Kemp, S A, Dhar, M S, Papa, G, Meng, B, Ferreira, I A T M, Datir, R, Collier, D A, Albecka, A, Singh, S, Pandey, R, Brown, J, Zhou, J, Goonawardane, N, Mishra, S, Whittaker, C, Mellan, T, Marwal, R, Datta, M, Sengupta, S, Ponnusamy, K, Radhakrishnan, V S, Abdullahi, A, Charles, O, Chattopadhyay, P, Devi, P, Caputo, D, Peacock, T, Wattal, C, Goel, N, Satwik, A, Vaishya, R, Agarwal, M, Chauhan, H, Chauhan, H, Dikid, T, Gogia, H, Lall, H, Verma, K, Dhar, M S, Singh, M K, Soni, N, Meena, N, Madan, P, Singh, P, Sharma, R, Sharma, R, Kabra, S, Kumar, S, Kumari, S, Sharma, U, Chaudhary, U, Sivasubbu, S, Scaria, V, Oberoi, J K, Raveendran, R, Datta, S, Das, S, Maitra, A, Chinnaswamy, S, Biswas, N K, Parida, A, Raghav, S K, Prasad, P, Sarin, A, Mayor, S, Ramakrishnan, U, Palakodeti, D, Seshasayee, A S N, Thangaraj, K, Bashyam, M D, Dalal, A, Bhat, M, Shouche, Y, Pillai, A, Abraham, P, Potdar, V A, Cherian, S S, Desai, A S, Pattabiraman, C, Manjunatha, M V, Mani, R S, Udupi, G A, Nandicoori, V, Tallapaka, K B, Sowpati, D T, Kawabata, R, Kawabata, R, Morizako, N, Sadamasu, K, Asakura, H, Nagashima, M, Yoshimura, K, Ito, J, Kimura, I, Uriu, K, Kosugi, Y, Suganami, M, Oide, A, Yokoyama, M, Chiba, M, Saito, A, Butlertanaka, E P, Tanaka, Y L, Ikeda, T, Motozono, C, Nasser, H, Shimizu, R, Yuan, Y, Kitazato, K, Hasebe, H, Nakagawa, S, Wu, J, Takahashi, M, Fukuhara, T, Shimizu, K, Tsushima, K, Kubo, H, Shirakawa, K, Kazuma, Y, Nomura, R, Horisawa, Y, Takaori-Kondo, A, Tokunaga, K, Ozono, S, Baker, S, Baker, S, Dougan, G, Hess, C, Kingston, N, Lehner, P J, Lyons, P A, Matheson, N J, Owehand, W H, Saunders, C, Summers, C, Thaventhiran, J E D, Toshner, M, Weekes, M P, Maxwell, P, Shaw, A, Bucke, A, Calder, J, Canna, L, Domingo, J, Elmer, A, Fuller, S, Harris, J, Hewitt, S, Kennet, J, Jose, S, Kourampa, J, Meadows, A, O'Brien, C, Price, J, Publico, C, Rastall, R, Ribeiro, C, Rowlands, J, Ruffolo, V, Tordesillas, H, Bullman, B, Dunmore, B J, Fawke, S, Graf, S, Hodgson, J, Huang, C, Hunter, K, Jones, E, Legchenko, E, Matara, C, Martin, J, Mescia, F, O'Donnell, C, Pointon, L, Pond, N, Shih, J, Sutcliffe, R, Tilly, T, Treacy, C, Tong, Z, Wood, J, Wylot, M, Bergamaschi, L, Betancourt, A, Bower, G, Cossetti, C, De Sa, A, Epping, M, Fawke, S, Gleadall, N, Grenfell, R, Hinch, A, Huhn, O, Jackson, S, Jarvis, I, Krishna, B, Lewis, D, Marsden, J, Nice, F, Okecha, G, Omarjee, O, Perera, M, Potts, M, Richoz, N, Romashova, V, Yarkoni, N S, Sharma, R, Stefanucci, L, Stephens, J, Strezlecki, M, Turner, L, De Bie, E M D D, Bunclark, K, Josipovic, M, Mackay, M, Rossi, S, Selvan, M, Spencer, S, Yong, C, Allison, J, Butcher, H, Caputo, D, Clapham-Riley, D, Dewhurst, E, Furlong, A, Graves, B, Gray, J, Ivers, T, Kasanicki, M, Le Gresley, E, Linger, R, Meloy, S, Muldoon, F, Ovington, N, Papadia, S, Phelan, I, Stark, H, Stirrups, K E, Townsend, P, Walker, N, Webster, J, Scholtes, I, Hein, S, King, R, Mavousian, A, Lee, J H, Bassi, J, Silacci-Fegni, C, Saliba, C, Pinto, D, Irie, T, Yoshida, I, Hamilton, W L, Sato, K, Bhatt, S, Flaxman, S, James, L C, Corti, D, Piccoli, L, Barclay, W S, Rakshit, P, Agrawal, A, Gupta, R K & Mishra, S 2021, ' SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion ', Nature, vol. 599, pp. 114-119 . https://doi.org/10.1038/s41586-021-03944-y
Nature
Nature
The B.1.617.2 (Delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in the state of Maharashtra in late 2020 and spread throughout India, outcompeting pre-existing lineages including B.1.617.1 (Kappa) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d15d086906aa18db47f0ee053650ce
https://doi.org/10.1038/s41586-021-03944-y
https://doi.org/10.1038/s41586-021-03944-y
Autor:
Meng, Bo, Abdullahi, Adam, Ferreira, Isabella ATM, Goonawardane, Niluka, Saito, Akatsuki, Kimura, Izumi, Yamasoba, Daichi, Gerber, Pehuén Pereyra, Fatihi, Saman, Rathore, Surabhi, Zepeda, Samantha K, Papa, Guido, Kemp, Steven, Ikeda, Terumasa, Toyoda, Mako, Tan, Toong Seng, Kuramochi, Jin, Mitsunaga, Shigeki, Ueno, Takamasa, Shirakawa, Kotaro, Takaori-Kondo, Akifumi, Brevini, Teresa, Mallery, Donna L, Charles, Oscar J, CITIID-NIHR BioResource COVID-19 Collaboration, Genotype To Phenotype Japan (G2P-Japan) Consortium, Ecuador-COVID19 Consortium, Bowen, John E, Joshi, Anshu, Walls, Alexandra C, Jackson, Laurelle, Martin, Darren, Smith, Kenneth, Bradley, John, Briggs, John AG, Choi, Jinwook, Madissoon, Elo, Meyer, Kerstin B, Mlcochova, Petra, Ceron-Gutierrez, Lourdes, Doffinger, Rainer, Teichmann, Sarah, Fisher, Andrew J, Pizzuto, Matteo S, De Marco, Anna, Corti, Davide, Hosmillo, Myra, Lee, Joo, James, Leo C, Thukral, Lipi, Veesler, David, Sigal, Alex, Sampaziotis, Fotios, Goodfellow, Ian G, Matheson, Nicholas J, Sato, Kei, Gupta, Ravindra
The SARS-CoV-2 Omicron BA.1 variant emerged in 20211 and has multiple mutations in its spike protein2. Here we show that the spike protein of Omicron has a higher affinity for ACE2 compared with Delta, and a marked change in its antigenicity increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4783eb7570e97c73e0fe2a43f7044f8
Autor:
Meng, Bo, Kemp, Steven A, Papa, Guido, Datir, Rawlings, Ferreira, Isabella ATM, Marelli, Sara, Harvey, William T, Lytras, Spyros, Mohamed, Ahmed, Gallo, Giulia, Thakur, Nazia, Collier, Dami A, Mlcochova, Petra, COVID-19 Genomics UK (COG-UK) Consortium, Duncan, Lidia M, Carabelli, Alessandro M, Kenyon, Julia C, Lever, Andrew M, De Marco, Anna, Saliba, Christian, Culap, Katja, Cameroni, Elisabetta, Matheson, Nicholas J, Piccoli, Luca, Corti, Davide, James, Leo C, Robertson, David L, Bailey, Dalan, Gupta, Ravindra K
Publikováno v:
Cell reports, vol 35, iss 13
We report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ΔH69/V70 in multiple independent lineages, often occurring after acquisition of receptor binding motif replacements such as N439K and Y453F, known to increase binding affin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4febb581039282ecd061e3308366ee51
https://www.repository.cam.ac.uk/handle/1810/326096
https://www.repository.cam.ac.uk/handle/1810/326096