Granzyme B-based cytolytic fusion protein targeting EpCAM specifically kills triple negative breast cancer cells in vitro and inhibits tumor growth in a subcutaneous mouse tumor model

Autor: Amoury, Manal, Kolberg, Katharina, Pham, Anh-Tuan, Hristodorov, Dmitrij, Mladenov, Radoslav, Di Fiore, Stefano, Helfrich, Wijnand, Kiessling, Fabian, Fischer, Rainer, Pardo, Alessa, Thepen, Theophilus, Hussain, Ahmad F., Nachreiner, Thomas, Barth, Stefan ^*

Publikováno v: In Cancer Letters 28 March 2016 372(2):201-209

A CSPG4-specific immunotoxin kills rhabdomyosarcoma cells and binds to primary tumor tissues

Autor: Brehm, Hannes, Niesen, Judith, Mladenov, Radoslav, Stein, Christoph, Pardo, Alessa, Fey, Georg, Helfrich, Wijnand, Fischer, Rainer, Gattenlöhner, Stefan, Barth, Stefan

Publikováno v: In Cancer Letters 1 October 2014 352(2):228-235

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Macrophage-Targeted Therapy: CD64-Based Immunotoxins for Treatment of Chronic Inflammatory Diseases.

Autor: Hristodorov, Dmitrij¹ dmitrij.hristodorov@rwth-aachen.de, Mladenov, Radoslav¹ radoslav.mladenov@rwth-aachen.de, Huhn, Michael¹ michael.huhn@molbiotech.rwth-aachen.de, Barth, Stefan^1,2 barth@hia.rwth-aachen.de, Thepen, Theo² thepen@ime.fraunhofer.de

Publikováno v: Toxins. Sep2012, Vol. 4 Issue 9, p676-694. 19p. 3 Diagrams.

Evaluation of FcR-directed immunotherapeutic strategies to manipulate macrophages in in vitro and ex vivo models of chronic inflammation

Autor: Mladenov, Radoslav

Publikováno v: Aachen 1 Online-Ressource (115 Seiten) : Illustrationen, Diagramme (2016). doi:10.18154/RWTH-2016-11694 = Dissertation, RWTH Aachen University, 2016

RWTH Aachen University, Diss., 2016; 115 pp., (2016).
Macrophages are a fundamental part of the immune system and are responsible for diverse physiological processes including inflammation, tissue repair and homeostasis. Displaying extraordinary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5bea3a457181328433517c136abb90