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Autor:
Justin A. Colacino, Sadeesh K. Ramakrishnan, Nupur K. Das, Mladen T. Jurkovic, Chesta Jain, Elizabeta Nemeth, Andrew J. Schwartz, Yatrik M. Shah, Jun Wu, Samira Lakhal-Littleton
Publikováno v:
The Journal of clinical investigation, vol 129, iss 1
Iron-related disorders are among the most prevalent diseases worldwide. Systemic iron homeostasis requires hepcidin, a liver-derived hormone that controls iron mobilization through its molecular target ferroportin (FPN), the only known mammalian iron