Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mladen, Tzvetkov"'
Autor:
Caspar Mewes, Tessa Alexander, Benedikt Büttner, José Hinz, Ayelet Alpert, Aron-F. Popov, Tim Beißbarth, Mladen Tzvetkov, Marian Grade, Michael Quintel, Ingo Bergmann, Ashham Mansur
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 22, p 5302 (2021)
(1) Background: Sepsis is a leading cause of death and a global public health problem. Accordingly, deciphering the underlying molecular mechanisms of this disease and the determinants of its morbidity and mortality is pivotal. This study examined th
Externí odkaz:
https://doaj.org/article/36888c994df64f12935d94fabe780b64
Autor:
Caspar Mewes, Tessa Alexander, Benedikt Büttner, José Hinz, Ayelet Alpert, Aron-F. Popov, Michael Ghadimi, Tim Beißbarth, Mladen Tzvetkov, Marian Grade, Michael Quintel, Ingo Bergmann, Ashham Mansur
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8318 (2020)
Background: Previous studies have reported the fundamental role of immunoregulatory proteins in the clinical phenotype and outcome of sepsis. This study investigated two functional single nucleotide polymorphisms (SNPs) of T cell immunoglobulin and m
Externí odkaz:
https://doaj.org/article/9e3ccf2fb7204b159b914bc367e1c038
Autor:
Julius Runzheimer, Caspar Mewes, Benedikt Büttner, José Hinz, Aron-Frederik Popov, Michael Ghadimi, Katalin Kristof, Tim Beissbarth, Joel Schamroth, Mladen Tzvetkov, Bastian Schmack, Michael Quintel, Ingo Bergmann, Ashham Mansur
Publikováno v:
Journal of Clinical Medicine, Vol 8, Iss 3, p 301 (2019)
Sepsis is a life-threatening condition and a significant challenge for those working in intensive care, where it remains one of the leading causes of mortality. According to the sepsis-3 definition, sepsis is characterized by dysregulation of the hos
Externí odkaz:
https://doaj.org/article/55471699fcc54c48966dd58db7be06b3
Autor:
Ashham Mansur, Benjamin Liese, Maximilian Steinau, Michael Ghadimi, Ingo Bergmann, Mladen Tzvetkov, Aron Frederik Popov, Tim Beissbarth, Martin Bauer, José Hinz
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127761 (2015)
According to previous investigations, CD14 is suggested to play a pivotal role in initiating and perpetuating the pro-inflammatory response during sepsis. A functional polymorphism within the CD14 gene, rs2569190, has been shown to impact the pro-inf
Externí odkaz:
https://doaj.org/article/1e91e247e83d4fae8a2b4f08f8ae7e37
Autor:
Ashham Mansur, Maximilian Steinau, Aron Frederik Popov, Sinisa Milenovic, Christian Bireta, Alexander Weymann, Hanna Schotola, Christoph H Wiese, Tim Beissbarth, Mladen Tzvetkov, José Hinz
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131155 (2015)
Genetic variants within the endothelin-1 gene (EDN1) have been associated with several cardiovascular diseases and may act as genetic prognostic markers. Here, we explored the overall relevance of EDN1 polymorphisms for long-term survival in patients
Externí odkaz:
https://doaj.org/article/24307e114815412980fd140a8a02f5a0
Autor:
Caspar, Mewes, Benedikt, Büttner, José, Hinz, Ayelet, Alpert, Aron Frederik, Popov, Michael, Ghadimi, Tim, Beissbarth, Mladen, Tzvetkov, Shai, Shen-Orr, Ingo, Bergmann, Ashham, Mansur
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a surface protein on T cells, that has an inhibitory effect on the host immune reaction and prevents overreaction of the immune system. Because the functional single-nucleotide polymorphism (SNP
Autor:
Ulrich Schwantes, Danilo Wegner, Tobias Tadken, Eberhard Scheuch, Werner Siegmund, Hans-Ulrich Schulz, Christiane Modess, Mladen Tzvetkov, Bayew Tsega Abebe, Claudia Neumeister, Marleen J. Meyer, Michael Weiss
Publikováno v:
Journal of clinical pharmacologyReferences. 60(3)
Trospium chloride, a muscarinic receptor blocker, is poorly absorbed with different rates from areas in the jejunum and the cecum/ascending colon. To evaluate whether organic cation transporter (OCT) 1, OCT2 and multidrug and toxin extrusion (MATE) 1
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 141:1480-1482
Anamnese und klinischer Befund | Eine 79-jahrige Patientin ohne bekannten Diabetes mellitus wird mit einer schweren Hypoglykamie (Blut-Glukose: 36 mg / dl und Glasgow-Coma-Scale Score von 3) eingeliefert. Die Glukosewerte stabilisieren sich prompt un
Autor:
José Hinz, Benedikt Büttner, Fabian Kriesel, Maximilian Steinau, Aron Frederik Popov, Michael Ghadimi, Tim Beissbarth, Mladen Tzvetkov, Ingo Bergmann, Ashham Mansur
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
A recent genome-wide association study showed that a genetic variant within the FER gene is associated with survival in patients with sepsis due to pneumonia. Because severe pneumonia is the main cause of acute respiratory distress syndrome (ARDS), w
Publikováno v:
Deutsche medizinische Wochenschrift (1946). 141(20)