Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Mkrtchian S"'
Autor:
Yang, T., Xu, G., Newton, P.T., Chagin, A.S., Mkrtchian, S., Carlström, M., Zhang, X.-M., Harris, R.A., Cooter, M., Berger, M., Maddipati, K.R., Akassoglou, K., Terrando, N.
Publikováno v:
In British Journal of Anaesthesia March 2019 122(3):350-360
Autor:
Sheldrake, Helen M., Travica, S., Johansson, I., Loadman, Paul, Sutherland, Mark, Elsalem, Lina M.I., Illingworth, Nicola A., Cresswell, Alexander J., Reuillon, Tristan, Shnyder, Steven, Mkrtchian, S., Searcey, M., Ingelman-Sundberg, M., Patterson, Laurence H., Pors, Klaus
Yes
A library of duocarmycin bioprecursors based on the CPI and CBI scaffolds was synthesized and used to probe selective activation by cells expressing CYP1A1 and 2W1, CYPs known to be expressed in high frequency in some tumors. Several CPI-bas
A library of duocarmycin bioprecursors based on the CPI and CBI scaffolds was synthesized and used to probe selective activation by cells expressing CYP1A1 and 2W1, CYPs known to be expressed in high frequency in some tumors. Several CPI-bas
Externí odkaz:
http://hdl.handle.net/10454/9998
Autor:
Travica, S., Pors, Klaus, Loadman, Paul, Shnyder, Steven, Johansson, I., Alandas, Mohammed N., Sheldrake, Helen M., Mkrtchian, S., Patterson, Laurence H., Ingelman-Sundberg, M.
PURPOSE: Cytochrome P450 2W1 (CYP2W1) is a monooxygenase detected in 30% of colon cancers, whereas its expression in nontransformed adult tissues is absent, rendering it a tumor-specific drug target for development of novel colon cancer chemotherapy.
Externí odkaz:
http://hdl.handle.net/10454/6217
Autor:
Lauschke, VM, Vorrink, SU, Moro, SML, Rezayee, F, Nordling, A, Hendriks, DFG, Bell, CC, Sison-Young, R, Park, BK, Goldring, CE, Ellis, E, Johansson, I, Mkrtchian, S, Andersson, TB, Ingelman-Sundberg, M
Publikováno v:
HEPATOLOGY
Hepatocytes are dynamic cells that, upon injury, can alternate between nondividing differentiated and dedifferentiated proliferating states in vivo . However, in two‐dimensional cultures, primary human hepatocytes (PHHs) rapidly dedifferentiate, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::81aad76cea98d7954ea6bdc8c5f9b00d
http://livrepository.liverpool.ac.uk/3006888/1/miRNA_manuscript_240716_flat_changesaccepted.docx
http://livrepository.liverpool.ac.uk/3006888/1/miRNA_manuscript_240716_flat_changesaccepted.docx
Akademický článek
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ERp29 is an endoplasmic reticulum (ER) luminal protein with a putative secretion factor/escort chaperone function. Accumulated evidence has implicated ERp29 in the thyroglobulin secretion, polyoma virus transport and recently in carcinogenesis. ERp29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::9a9d04106afd966c64841751db2d37ed
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3149740
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3149740
Autor:
Christis, C., Fullaondo, A., Schildknegt, D., Mkrtchian, S., Heck, A.J.R., Braakman, L.J., Biomolecular Mass Spectrometry and Proteomics, Cellular Protein Chemistry, Dep Scheikunde, Sub Cellular Protein Chemistry, Sub Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spectrometry & Proteom.
Publikováno v:
Journal of Cell Science, 123(5), 787. Company of Biologists Ltd
Stimulation of thyrocytes with thyroid stimulating hormone (TSH) leads to a morphological change and a massive increase in thyroglobulin (Tg) production. Although Tg is a demanding client of the endoplasmic reticulum (ER), its increase did not result
Akademický článek
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Cancer cells are committed to an actively secretory state that facilitates communication with their microenvironment. We have addressed the role of ERp29, a novel endoplasmic reticulum secretion factor in mammary carcinogenesis using MCF-7 human brea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::ea0e72c72fb52a8cfc95ca252b13753b
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3095239
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3095239
Akademický článek
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