Zobrazeno 1 - 10 of 109 pro vyhledávání: '"Mk, Gately"'
1
Analysis of the multiple interactions between IL-12 and the high affinity IL-12 receptor complex
Autor: Dh, Presky, Lj, Minetti, Silke Gillessen, Vl, Wilkinson, Cy, Wu, Gubler U, Chizzonite R, Mk, Gately
Publikováno v: Europe PubMed Central
IL-12 is a heterodimeric cytokine, composed of a p40 and a p35 subunit, that exerts its biological effects by binding to specific cell surface receptors. Two IL-12R proteins, designated human IL-12 (huIL-12) receptor beta1 (huIL-12Rbeta1) and huIL-12
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::373c706583af53a1462b8878726aabfa
https://pubmed.ncbi.nlm.nih.gov/9498755
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2
IL-12 protects immunocompetent and immunodeficient neonatal mice against infection with Cryptosporidium parvum
Autor: Joseph Urban, Fayer R, Sj, Chen, Wc, Gause, Mk, Gately, Fd, Finkelman
Publikováno v: Europe PubMed Central
The protozoan parasite Cryptosporidium parvum (Cp) causes diarrhea that can be acutely severe in immunocompetent persons and can become chronic and life-threatening in immunocompromised individuals. Because studies in mice have implicated IFN-gamma i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f230a373ec26939dda367637b205fcc1
https://pubmed.ncbi.nlm.nih.gov/8598471
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3
In vitro maturation of neonatal human CD8 T lymphocytes into IL-4- and IL-5-producing cells
Autor: Dg, Byun, Christian E. Demeure, Lp, Yang, Shu U, Ishihara H, Vezzio N, Mk, Gately, Delespesse G
Publikováno v: Europe PubMed Central
Naive CD8 T cells isolated from umbilical cord blood were examined for cytokine production and for surface phenotype before and after priming with anti-CD3 mAb in the presence of selected cytokines. On stimulation with anti-CD3 immobilized on CD32-B7
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::be29657048fa90dccfeda7a676bba005
https://pubmed.ncbi.nlm.nih.gov/7963550
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4
IL-12 regulates T helper type 1 cytokine responses in human infectious disease
Autor: PA Sieling, X Wang, MK Gately, JL Oliveros, T McHugh, PF Barnes, SF Wolf, L Golkar, M Yamamura, Y Yogi, K Uyemura, TH Rea, RL Modlin
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 153(8)
We investigated the role of IL-12 in regulating T cell and cytokine responses in human infectious disease by using the spectrum of leprosy as a model. Tuberculoid patients mount strong T cell responses to Mycobacterium leprae, with production of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8212585dfe48b71c149cefa3c89c5d15
https://pubmed.ncbi.nlm.nih.gov/7930584
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5
Hydrocortisone suppresses the generation of nonspecific 'anomalous' killers but not specific cytolytic T lymphocytes in human mixed lymphocyte-tumor cultures
Autor: LM Muul, MK Gately
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 132(3)
Interpretation of results with the use of effector populations generated in human mixed lymphocyte tumor cultures (MLTC) has in many cases been clouded by the presence of two distinct cytolytic effectors: specific cytolytic T lymphocytes (CTL) and no
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a52e84f7f97b93d08cedd3cd6e98a67
https://pubmed.ncbi.nlm.nih.gov/6198383
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7
Akademický článek
Measurement of human and mouse interleukin-12.
Autor: Gately MK; Hoffmann-La Roche Inc, Nutley, New Jersey., Chizzonite R; Hoffmann-La Roche Inc, Nutley, New Jersey., Presky DH; Hoffmann-La Roche Inc, Nutley, New Jersey.
Publikováno v: Current protocols in immunology [Curr Protoc Immunol] 2001 May; Vol. Chapter 6, pp. 6.16.1-6.16.15.
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8
Akademický článek
In vitro and in vivo responses to interleukin 12 are maintained until the late SIV infection stage but lost during AIDS.
Autor: Villinger F; Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia 30322, USA. fvillin@emory.edu, Bucur S, Chikkala NF, Brar SS, Bostik P, Mayne AE, Adams J, Lee ME, Novembre FJ, Gately MK, Ansari AA, Hillyer CD
Publikováno v: AIDS research and human retroviruses [AIDS Res Hum Retroviruses] 2000 May 20; Vol. 16 (8), pp. 751-63.
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9
Akademický článek
Down-regulation of the pharmacokinetic-pharmacodynamic response to interleukin-12 during long-term administration to patients with renal cell carcinoma and evaluation of the mechanism of this "adaptive response" in mice.
Autor: Rakhit A; Department of Clinical Pharmacology, Hoffmann-La Roche Inc, Nutley, NJ 07110, USA., Yeon MM, Ferrante J, Fettner S, Nadeau R, Motzer R, Bukowski R, Carvajal DM, Wilkinson VL, Presky DH, Magram J, Gately MK
Publikováno v: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 1999 Jun; Vol. 65 (6), pp. 615-29.
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10
Akademický článek
IL-12 is dispensable for innate and adaptive immunity against low doses of Listeria monocytogenes.
Autor: Brombacher F; Max-Planck-Institute for Immunobiology, Freiburg, Germany., Dorfmüller A, Magram J, Dai WJ, Köhler G, Wunderlin A, Palmer-Lehmann K, Gately MK, Alber G
Publikováno v: International immunology [Int Immunol] 1999 Mar; Vol. 11 (3), pp. 325-32.
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