Atherosclerotic plaque injury-mediated murine thrombosis models: advantages and limitations

Autor: MFA Karel, B. Hechler, MJE Kuijpers, JMEM Cosemans

Publikováno v: Platelets, Vol 31, Iss 4, Pp 439-446 (2020)

In spite of current treatment strategies, myocardial infarction and stroke are still major causes of death worldwide. These events are triggered by damage of an atherosclerotic plaque, resulting in occlusive thrombus formation. Mouse studies have sig

Externí odkaz: https://doaj.org/article/d0e17a3ac0b34639a23f621a5b02e38d

Suppressed ORAI1-STIM1-dependent Ca ²⁺ entry by protein kinase C isoforms regulating platelet procoagulant activity.

Autor: Zou J; Synapse Research Institute Maastricht, Kon. Emmaplein 7, 6217 KD Maastricht, The Netherlands; Department of Biochemistry, CARIM, 6200 MD Maastricht University, Maastricht, The Netherlands., Zhang P; Department of Biochemistry, CARIM, 6200 MD Maastricht University, Maastricht, The Netherlands; Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany; Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V, Dortmund, Germany., Solari FA; Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V, Dortmund, Germany., Schönichen C; Department of Biochemistry, CARIM, 6200 MD Maastricht University, Maastricht, The Netherlands; Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Provenzale I; Department of Biochemistry, CARIM, 6200 MD Maastricht University, Maastricht, The Netherlands., Mattheij NJA; Department of Clinical Chemistry and Hematology, Maxima Medical Center Veldhoven, 5500 MB Veldhoven, The Netherlands., Kuijpers MJE; Department of Biochemistry, CARIM, 6200 MD Maastricht University, Maastricht, The Netherlands., Rauch JS; Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V, Dortmund, Germany., Swieringa F; Synapse Research Institute Maastricht, Kon. Emmaplein 7, 6217 KD Maastricht, The Netherlands., Sickmann A; Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V, Dortmund, Germany; Medizinische Fakultät, Medizinische Proteom-Center, Ruhr-Universität Bochum, Germany; Department of Chemistry, College of Physical Sciences, University of Aberdeen, United Kingdom., Zieger B; Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, University of Freiburg, Freiburg, Germany., Jurk K; Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Heemskerk JWM; Synapse Research Institute Maastricht, Kon. Emmaplein 7, 6217 KD Maastricht, The Netherlands; Department of Biochemistry, CARIM, 6200 MD Maastricht University, Maastricht, The Netherlands.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2024 Oct 16, pp. 107899. Date of Electronic Publication: 2024 Oct 16.

Design, manufacturing and testing of a green non-isocyanate polyurethane prosthetic heart valve.

Autor: Melo SF; Laboratory of Cardiology, GIGA-Cardiovascular Sciences, University of Liège, Avenue de l'Hôpital 11, B34, 4000 Liège, Belgium. cecile.oury@uliege.be., Nondonfaz A; Laboratory of Cardiology, GIGA-Cardiovascular Sciences, University of Liège, Avenue de l'Hôpital 11, B34, 4000 Liège, Belgium. cecile.oury@uliege.be., Aqil A; Center for Education and Research on Macromolecules (CERM), CESAM Research Unit, Department of Chemistry, University of Liège, Allée du 6 août 13, B6a, 4000 Liège, Belgium., Pierrard A; Center for Education and Research on Macromolecules (CERM), CESAM Research Unit, Department of Chemistry, University of Liège, Allée du 6 août 13, B6a, 4000 Liège, Belgium., Hulin A; Laboratory of Cardiology, GIGA-Cardiovascular Sciences, University of Liège, Avenue de l'Hôpital 11, B34, 4000 Liège, Belgium. cecile.oury@uliege.be., Delierneux C; Laboratory of Cardiology, GIGA-Cardiovascular Sciences, University of Liège, Avenue de l'Hôpital 11, B34, 4000 Liège, Belgium. cecile.oury@uliege.be., Ditkowski B; Laboratory of Cardiology, GIGA-Cardiovascular Sciences, University of Liège, Avenue de l'Hôpital 11, B34, 4000 Liège, Belgium. cecile.oury@uliege.be., Gustin M; Laboratory of Cardiology, GIGA-Cardiovascular Sciences, University of Liège, Avenue de l'Hôpital 11, B34, 4000 Liège, Belgium. cecile.oury@uliege.be., Legrand M; Sirris, Liège Science Park, Rue du Bois Saint-Jean 12, 4102 Seraing, Belgium., Tullemans BME; Cardiovascular Research Institute Maastricht (CARIM), Department of Biochemistry, Maastricht University, Universiteitssingel 50, 6200 MD Maastricht, The Netherlands., Brouns SLN; Cardiovascular Research Institute Maastricht (CARIM), Department of Biochemistry, Maastricht University, Universiteitssingel 50, 6200 MD Maastricht, The Netherlands., Nchimi A; Laboratory of Cardiology, GIGA-Cardiovascular Sciences, University of Liège, Avenue de l'Hôpital 11, B34, 4000 Liège, Belgium. cecile.oury@uliege.be., Carrus R; Sirris, Liège Science Park, Rue du Bois Saint-Jean 12, 4102 Seraing, Belgium., Dejosé A; Sirris, Liège Science Park, Rue du Bois Saint-Jean 12, 4102 Seraing, Belgium., Heemskerk JWM; Cardiovascular Research Institute Maastricht (CARIM), Department of Biochemistry, Maastricht University, Universiteitssingel 50, 6200 MD Maastricht, The Netherlands., Kuijpers MJE; Cardiovascular Research Institute Maastricht (CARIM), Department of Biochemistry, Maastricht University, Universiteitssingel 50, 6200 MD Maastricht, The Netherlands., Ritter J; Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Medical Faculty RWTH Aachen University, Pauwelsstraße 20, 52074 Aachen, Germany., Steinseifer U; Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Medical Faculty RWTH Aachen University, Pauwelsstraße 20, 52074 Aachen, Germany., Clauser JC; Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Medical Faculty RWTH Aachen University, Pauwelsstraße 20, 52074 Aachen, Germany., Jérôme C; Center for Education and Research on Macromolecules (CERM), CESAM Research Unit, Department of Chemistry, University of Liège, Allée du 6 août 13, B6a, 4000 Liège, Belgium., Lancellotti P; Laboratory of Cardiology, GIGA-Cardiovascular Sciences, University of Liège, Avenue de l'Hôpital 11, B34, 4000 Liège, Belgium. cecile.oury@uliege.be., Oury C; Laboratory of Cardiology, GIGA-Cardiovascular Sciences, University of Liège, Avenue de l'Hôpital 11, B34, 4000 Liège, Belgium. cecile.oury@uliege.be.

Publikováno v: Biomaterials science [Biomater Sci] 2024 Apr 16; Vol. 12 (8), pp. 2149-2164. Date of Electronic Publication: 2024 Apr 16.

Endothelium-mediated regulation of platelet activation: Involvement of multiple protein kinases.

Autor: Provenzale I; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.; Institute for Cardiovascular and Metabolic Research (ICMR), School of Biological Sciences, University of Reading, Reading, UK.; Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany., Solari FA; Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany., Schönichen C; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.; Center for Thrombosis and Haemostasis, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Brouns SLN; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands., Fernández DI; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.; Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Kuijpers MJE; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.; Thrombosis Expertise Center, Heart and Vascular Center, Maastricht University Medical Center+, Maastricht, The Netherlands., van der Meijden PEJ; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.; Thrombosis Expertise Center, Heart and Vascular Center, Maastricht University Medical Center+, Maastricht, The Netherlands., Gibbins JM; Institute for Cardiovascular and Metabolic Research (ICMR), School of Biological Sciences, University of Reading, Reading, UK., Sickmann A; Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany.; Medizinische Fakultät, Medizinische Proteom-Center, Ruhr-Universität Bochum, Bochum, Germany.; Department of Chemistry, College of Physical Sciences, University of Aberdeen, Aberdeen, UK., Jones C; Institute for Cardiovascular and Metabolic Research (ICMR), School of Biological Sciences, University of Reading, Reading, UK., Heemskerk JWM; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.; Synapse Research Institute Maastricht, Maastricht, The Netherlands.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Feb 29; Vol. 38 (4), pp. e23468.

Antagonistic Roles of Human Platelet Integrin αIIbβ3 and Chemokines in Regulating Neutrophil Activation and Fate on Arterial Thrombi Under Flow.

Autor: Schönichen C; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands (C.S., S.L.N.B., J.M.E.M.C., R.R.K., S.P.W., M.J.E.K., J.W.M.H., M.N.).; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg-University of Mainz, Germany (C.S., K.J.)., Montague SJ; Institute of Cardiovascular Sciences, The Medical School, University of Birmingham, United Kingdom (S.J.M., S.P.W.)., Brouns SLN; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands (C.S., S.L.N.B., J.M.E.M.C., R.R.K., S.P.W., M.J.E.K., J.W.M.H., M.N.)., Burston JJ; Systems Immunity Research Institute, School of Medicine, Cardiff University, United Kingdom (J.J.B., V.B.O.)., Cosemans JMEM; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands (C.S., S.L.N.B., J.M.E.M.C., R.R.K., S.P.W., M.J.E.K., J.W.M.H., M.N.)., Jurk K; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg-University of Mainz, Germany (C.S., K.J.).; Department of Anaesthesiology and Intensive Care, University Hospital Muenster, Germany (K.J., B.E.K.)., Kehrel BE; Department of Anaesthesiology and Intensive Care, University Hospital Muenster, Germany (K.J., B.E.K.)., Koenen RR; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands (C.S., S.L.N.B., J.M.E.M.C., R.R.K., S.P.W., M.J.E.K., J.W.M.H., M.N.)., Ní Áinle F; School of Medicine, University College Dublin, Ireland (F.N.Á.).; Department of Haematology, Mater Misericordiae University Hospital and Rotunda Hospital, Dublin, Ireland (F.N.Á.)., O'Donnell VB; Systems Immunity Research Institute, School of Medicine, Cardiff University, United Kingdom (J.J.B., V.B.O.)., Soehnlein O; Institute for Cardiovascular Prevention, Ludwig-Maximilians-Universität München, Germany (O.S.).; Institute for Experimental Pathology, Center for Molecular Biology of Inflammation, Westfälische Wilhelms Universität, Münster, Germany (O.S.).; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (O.S.)., Watson SP; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands (C.S., S.L.N.B., J.M.E.M.C., R.R.K., S.P.W., M.J.E.K., J.W.M.H., M.N.).; Institute of Cardiovascular Sciences, The Medical School, University of Birmingham, United Kingdom (S.J.M., S.P.W.).; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, the Midlands, United Kingdom (S.P.W.)., Kuijpers MJE; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands (C.S., S.L.N.B., J.M.E.M.C., R.R.K., S.P.W., M.J.E.K., J.W.M.H., M.N.).; Thrombosis Expertise Centre, Heart and Vascular Centre, Maastricht University Medical Centre, the Netherlands (M.J.E.K.)., Heemskerk JWM; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands (C.S., S.L.N.B., J.M.E.M.C., R.R.K., S.P.W., M.J.E.K., J.W.M.H., M.N.).; Synapse Research Institute, Maastricht, the Netherlands (J.W.M.H.)., Nagy M; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands (C.S., S.L.N.B., J.M.E.M.C., R.R.K., S.P.W., M.J.E.K., J.W.M.H., M.N.).

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2023 Sep; Vol. 43 (9), pp. 1700-1712. Date of Electronic Publication: 2023 Jul 06.