Zobrazeno 1 - 10 of 126 pro vyhledávání: '"Mj, Stadecker"'
1
In situ analysis of B7-2 costimulatory, major histocompatibility complex class II, and adhesion molecule expression in schistosomal egg granulomas
Autor: Rathore A, Sacristán C, Ricklan DE, Pedro Flores-Villanueva, Mj, Stadecker
Publikováno v: Europe PubMed Central
Immunopathological damage in schistosomiasis consist of egg granuloma formation, which is a hypersensitivity reaction mediated by antigen-specific CD4+ T helper (Th) lymphocytes. Th cells are dependent on accessory cell-bound co-stimulatory signals f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a9a3dea42c9369123f8545edfa34bc01
https://pubmed.ncbi.nlm.nih.gov/8686742
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2
Recombinant IL-10 and IL-10/Fc treatment down-regulate egg antigen-specific delayed hypersensitivity reactions and egg granuloma formation in schistosomiasis
Autor: Pedro Flores-Villanueva, Xx, Zheng, Tb, Strom, Mj, Stadecker
Publikováno v: Europe PubMed Central
In infection with the helminth Schistosoma mansoni, parasite eggs elicit a Th cell-mediated hepatic granulomatous inflammation that leads to scarring, portal hypertension, hemorrhage, and death. On the other hand, the cytokine IL-10 has been shown to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bcbe65756983570ec06215e042436eb1
https://pubmed.ncbi.nlm.nih.gov/8617955
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3
In situ analysis of cytokine responses in experimental murine schistosomiasis
Autor: Sa, Bogen, Pedro Flores-Villanueva, Me, Mccusker, Fogelman I, Garifallou M, Es, El-Attar, Kwan P, Mj, Stadecker
Publikováno v: Europe PubMed Central
Infection with schistosomiasis results in CD4+ T helper (Th) cell-dependent granulomatous inflammation around parasite eggs. T cell-derived cytokines play a critical role in the induction and subsequent down-modulation of the granulomas. These cytoki
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fb6e380fb1423c99a6da7c57826efd89
https://pubmed.ncbi.nlm.nih.gov/7637326
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4
Role of IL-10 on antigen-presenting cell function for schistosomal egg-specific monoclonal T helper cell responses in vitro and in vivo
Autor: Pedro Flores-Villanueva, Sm, Chikunguwo, Ts, Harris, Mj, Stadecker
Publikováno v: Europe PubMed Central
Egg Ag-stimulated lymphoid cell culture supernatants from schistosome-infected mice significantly inhibited Ag-specific, MHC-restricted proliferative responses of cloned schistosomal egg Ag-specific CD4+, Th-1-type lymphocytes. The inhibitory molecul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::45e80e9ffc856d076fe59d4cdc3918e7
https://pubmed.ncbi.nlm.nih.gov/8376775
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6
Regulation of T helper cell responses in experimental murine schistosomiasis by IL-10. Effect on expression of B7 and B7-2 costimulatory molecules by macrophages
Autor: Pedro Flores-Villanueva, Reiser H, Mj, Stadecker
Publikováno v: Europe PubMed Central
Granulomatous inflammation in schistosomiasis is a manifestation of cell-mediated hypersensitivity to parasite egg Ags that is predictably reduced in size over the course of the disease. This down-regulation may reflect a state of anergy in the T cel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b68b176bf6a25c17c87017a8992ba4e9
http://europepmc.org/abstract/med/7525726
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7
NLRP3 and AIM2 inflammasomes exacerbate the pathogenic Th17 cell response to eggs of the helminth Schistosoma mansoni .
Autor: Suresh Kumar Meena Kumari M; Department of Veterinary and Biomedical Sciences, Center for Molecular Immunology and Infectious Disease, Pennsylvania State University, University Park, Pennsylvania, United States of America., Liu P; Department of Veterinary and Biomedical Sciences, Center for Molecular Immunology and Infectious Disease, Pennsylvania State University, University Park, Pennsylvania, United States of America., Jump K; Department of Veterinary and Biomedical Sciences, Center for Molecular Immunology and Infectious Disease, Pennsylvania State University, University Park, Pennsylvania, United States of America., Morales Y; Department of Immunology, Tufts University School of Medicine, Boston, Massachusetts, United States of America., Miller EA; Department of Immunology, Tufts University School of Medicine, Boston, Massachusetts, United States of America., Shecter I; Department of Immunology, Tufts University School of Medicine, Boston, Massachusetts, United States of America., Stadecker MJ; Department of Immunology, Tufts University School of Medicine, Boston, Massachusetts, United States of America., Kalantari P; Department of Veterinary and Biomedical Sciences, Center for Molecular Immunology and Infectious Disease, Pennsylvania State University, University Park, Pennsylvania, United States of America.; Department of Immunology, Tufts University School of Medicine, Boston, Massachusetts, United States of America.
Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Mar 13. Date of Electronic Publication: 2024 Mar 13.
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8
Akademický článek
Obesity does not associate with 5-year surgical complications following anatomic total shoulder arthroplasty and reverse total shoulder arthroplasty.
Autor: Agarwal AR; Department of Orthopedic Surgery, George Washington Hospital, Washington, DC, USA. Electronic address: amil_agarwal@gwu.edu., Wang KY; Johns Hopkins Department of Orthopaedic Surgery, Columbia, MD, USA., Xu AL; Johns Hopkins Department of Orthopaedic Surgery, Columbia, MD, USA., Stadecker MJ; Department of Orthopedic Surgery, George Washington Hospital, Washington, DC, USA., Jami M; Johns Hopkins Department of Orthopaedic Surgery, Columbia, MD, USA., Miller A; Johns Hopkins Department of Orthopaedic Surgery, Columbia, MD, USA., Best MJ; Johns Hopkins Department of Orthopaedic Surgery, Columbia, MD, USA., Srikumaran U; Johns Hopkins Department of Orthopaedic Surgery, Columbia, MD, USA.
Publikováno v: Journal of shoulder and elbow surgery [J Shoulder Elbow Surg] 2023 May; Vol. 32 (5), pp. 947-957. Date of Electronic Publication: 2022 Nov 11.
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9
Akademický článek
The balance between gasdermin D and STING signaling shapes the severity of schistosome immunopathology.
Autor: Kalantari P; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111.; Department of Veterinary and Biomedical Sciences, Center for Molecular Immunology and Infectious Disease, The Pennsylvania State University, University Park, PA 16802., Shecter I; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111., Hopkins J; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111., Pilotta Gois A; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111., Morales Y; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111., Harandi BF; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111., Sharma S; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111., Stadecker MJ; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111.
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Mar 28; Vol. 120 (13), pp. e2211047120. Date of Electronic Publication: 2023 Mar 21.
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10
Akademický článek
The C-type Lectin Receptor-Driven, Th17 Cell-Mediated Severe Pathology in Schistosomiasis: Not All Immune Responses to Helminth Parasites Are Th2 Dominated.
Autor: Kalantari P; Department of Immunology, Tufts University School of Medicine, Boston, MA, United States., Bunnell SC; Department of Immunology, Tufts University School of Medicine, Boston, MA, United States., Stadecker MJ; Department of Immunology, Tufts University School of Medicine, Boston, MA, United States.
Publikováno v: Frontiers in immunology [Front Immunol] 2019 Jan 30; Vol. 10, pp. 26. Date of Electronic Publication: 2019 Jan 30 (Print Publication: 2019).
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