Effector target-guided engineering of an integrated domain expands the disease resistance profile of a rice NLR immune receptor

Autor: JHR Maidment, M Shimizu, S Vera, M Franceschetti, A Longya, CEM Stevenson, JC De la Concepcion, A Białas, S Kamoun, R Terauchi, MJ Banfield

A subset of plant intracellular NLR immune receptors detect effector proteins, secreted by phytopathogens to promote infection, through unconventional integrated domains which resemble the effector’s host targets. Direct binding of effectors to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a2bbc34be538d6854e48c0d0ef38015
https://doi.org/10.1101/2022.06.14.496076

Structure of TrkAIg2 and molecular modelling of the neurotrophin binding sites of the Trk receptors

Autor: Ags, Robertson, Richard Sessions, Mj, Banfield, Ja, Dando, Ggf, Mason, Ph, Holden, Shelley Allen, Sj, Tyler, Jj, Burston, Rl, Naylor, Gk, Wilcock, Rl, Brady, Dawbarn, D.

Publikováno v: University of Bristol-PURE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0a8bcd60f236e3cbc2ebd1bc9df032be
https://research-information.bris.ac.uk/en/publications/e6e1a4ef-c995-4d8b-9e01-9367641e7588

Activation of plant immunity through conversion of a helper NLR homodimer into a resistosome.

Autor: Selvaraj M; The Sainsbury Laboratory, University of East Anglia; Norwich Research Park, Norwich, United Kingdom., Toghani A; The Sainsbury Laboratory, University of East Anglia; Norwich Research Park, Norwich, United Kingdom., Pai H; The Sainsbury Laboratory, University of East Anglia; Norwich Research Park, Norwich, United Kingdom., Sugihara Y; The Sainsbury Laboratory, University of East Anglia; Norwich Research Park, Norwich, United Kingdom., Kourelis J; The Sainsbury Laboratory, University of East Anglia; Norwich Research Park, Norwich, United Kingdom., Yuen ELH; Imperial College London, London, United Kingdom., Ibrahim T; Imperial College London, London, United Kingdom., Zhao H; The Sainsbury Laboratory, University of East Anglia; Norwich Research Park, Norwich, United Kingdom., Xie R; The Sainsbury Laboratory, University of East Anglia; Norwich Research Park, Norwich, United Kingdom., Maqbool A; The Sainsbury Laboratory, University of East Anglia; Norwich Research Park, Norwich, United Kingdom., De la Concepcion JC; Department of Biochemistry and Metabolism, John Innes Centre, Norwich, United Kingdom., Banfield MJ; Department of Biochemistry and Metabolism, John Innes Centre, Norwich, United Kingdom., Derevnina L; The Sainsbury Laboratory, University of East Anglia; Norwich Research Park, Norwich, United Kingdom., Petre B; The Sainsbury Laboratory, University of East Anglia; Norwich Research Park, Norwich, United Kingdom., Lawson DM; Department of Biochemistry and Metabolism, John Innes Centre, Norwich, United Kingdom., Bozkurt TO; Imperial College London, London, United Kingdom., Wu CH; The Sainsbury Laboratory, University of East Anglia; Norwich Research Park, Norwich, United Kingdom., Kamoun S; The Sainsbury Laboratory, University of East Anglia; Norwich Research Park, Norwich, United Kingdom., Contreras MP; The Sainsbury Laboratory, University of East Anglia; Norwich Research Park, Norwich, United Kingdom.

Publikováno v: PLoS biology [PLoS Biol] 2024 Oct 18; Vol. 22 (10), pp. e3002868. Date of Electronic Publication: 2024 Oct 18 (Print Publication: 2024).

Zinc-finger (ZiF) fold secreted effectors form a functionally diverse family across lineages of the blast fungus Magnaporthe oryzae.

Autor: De la Concepcion JC; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich, United Kingdom.; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Langner T; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Fujisaki K; Division of Genomics and Breeding, Iwate Biotechnology Research Center, Iwate, Japan., Yan X; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Were V; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Lam AHC; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich, United Kingdom., Saado I; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich, United Kingdom., Brabham HJ; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Win J; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Yoshida K; Laboratory of Plant Genetics, Graduate School of Agriculture, Kyoto University, Kyoto, Japan., Talbot NJ; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Terauchi R; Division of Genomics and Breeding, Iwate Biotechnology Research Center, Iwate, Japan.; Laboratory of Crop Evolution, Graduate School of Agriculture, Kyoto University, Kyoto, Japan., Kamoun S; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, United Kingdom., Banfield MJ; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich, United Kingdom.

Publikováno v: PLoS pathogens [PLoS Pathog] 2024 Jun 17; Vol. 20 (6), pp. e1012277. Date of Electronic Publication: 2024 Jun 17 (Print Publication: 2024).

Allelic compatibility in plant immune receptors facilitates engineering of new effector recognition specificities.

Autor: Bentham AR; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK., De la Concepcion JC; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK., Benjumea JV; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK., Kourelis J; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich NR4 7UH, UK., Jones S; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK., Mendel M; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK., Stubbs J; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK., Stevenson CEM; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK., Maidment JHR; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich NR4 7UH, UK., Youles M; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich NR4 7UH, UK., Zdrzałek R; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK., Kamoun S; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich NR4 7UH, UK., Banfield MJ; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.

Publikováno v: The Plant cell [Plant Cell] 2023 Sep 27; Vol. 35 (10), pp. 3809-3827.