Pharmacogenetic studies of drug response in schizophrenia

Autor: C Gallego, Bárbara Arias, J Salazar, MJ Arranz

Publikováno v: Expert Review of Precision Medicine and Drug Development. 1:79-91

Treatment with antipsychotics is marred by frequent failure and adverse reactions. About a third of treated patients will not improve adequately, and more than 60% will develop severe and long-last...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14663dffb4e840595cbfd909fe2497c4
https://doi.org/10.1080/23808993.2016.1140554

Novel risk loci for COVID-19 hospitalization among admixed American populations.

Autor: Diz-de Almeida S; ERN-ITHACA-European Reference Network, Soria, Spain.; Pediatric Neurology Unit, Department of Pediatrics, Navarra Health Service Hospital, Pamplona, Spain.; CIBERER, ISCIII, Madrid, Spain.; Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Cruz R; ERN-ITHACA-European Reference Network, Soria, Spain.; Pediatric Neurology Unit, Department of Pediatrics, Navarra Health Service Hospital, Pamplona, Spain.; CIBERER, ISCIII, Madrid, Spain.; Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Luchessi AD; Universidade Federal do Rio Grande do Norte, Departamento de Analises Clinicas e Toxicologicas, Natal, Brazil., Lorenzo-Salazar JM; Genomics Division, Instituto Tecnológico y de Energías Renovables, Santa Cruz de Tenerife, Spain., de Heredia ML; CIBERER, ISCIII, Madrid, Spain., Quintela I; Fundación Pública Galega de Medicina Xenómica, Sistema Galego de Saúde (SERGAS), Santiago de Compostela, Spain., González-Montelongo R; Genomics Division, Instituto Tecnológico y de Energías Renovables, Santa Cruz de Tenerife, Spain., Nogueira Silbiger V; Universidade Federal do Rio Grande do Norte, Departamento de Analises Clinicas e Toxicologicas, Natal, Brazil., Porras MS; CIBERER, ISCIII, Madrid, Spain.; Instituto de Genética Médica y Molecular (INGEMM), Hospital Universitario La Paz IDIPAZ, Madrid, Spain., Tenorio Castaño JA; ERN-ITHACA-European Reference Network, Soria, Spain.; CIBERER, ISCIII, Madrid, Spain.; Instituto de Genética Médica y Molecular (INGEMM), Hospital Universitario La Paz IDIPAZ, Madrid, Spain., Nevado J; ERN-ITHACA-European Reference Network, Soria, Spain.; CIBERER, ISCIII, Madrid, Spain.; Instituto de Genética Médica y Molecular (INGEMM), Hospital Universitario La Paz IDIPAZ, Madrid, Spain., Aguado JM; Unit of Infectious Diseases, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.; Spanish Network for Research in Infectious Diseases (REIPI RD16/0016/0002), Instituto de Salud Carlos III, Madrid, Spain.; CIBERINFEC, ISCIII, Madrid, Spain., Aguilar C; Hospital General Santa Bárbara de Soria, Soria, Spain., Aguilera-Albesa S; Pediatric Neurology Unit, Department of Pediatrics, Navarra Health Service Hospital, Pamplona, Spain.; Navarra Health Service, NavarraBioMed Research Group, Pamplona, Spain., Almadana V; Hospital Universitario Virgen Macarena, Neumología, Sevilla, Spain., Almoguera B; CIBERER, ISCIII, Madrid, Spain.; Department of Genetics & Genomics, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain., Alvarez N; Spanish National Cancer Research Centre, Human Genotyping-CEGEN Unit, Madrid, Spain., Andreu-Bernabeu Á; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón (IiSGM), Madrid, Spain.; School of Medicine, Universidad Complutense, Madrid, Spain., Arana-Arri E; Biocruces Bizkai HRI, Bizkaia, Spain.; Cruces University Hospital, Osakidetza, Bizkaia, Spain., Arango C; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón (IiSGM), Madrid, Spain.; School of Medicine, Universidad Complutense, Madrid, Spain.; Centre for Biomedical Network Research on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain., Arranz MJ; Fundació Docència I Recerca Mutua Terrassa, Barcelona, Spain., Artiga MJ; Spanish National Cancer Research Centre, CNIO Biobank, Madrid, Spain., Baptista-Rosas RC; Hospital General de Occidente, Zapopan Jalisco, Mexico.; Centro Universitario de Tonalá, Universidad de Guadalajara, Tonalá Jalisco, Mexico.; Centro de Investigación Multidisciplinario en Salud, Universidad de Guadalajara, Tonalá Jalisco, Mexico., Barreda-Sánchez M; Universidad Católica San Antonio de Murcia (UCAM), Murcia, Spain.; Instituto Murciano de Investigación Biosanitaria (IMIB-Arrixaca), Murcia, Spain., Belhassen-Garcia M; Hospital Universitario de Salamanca-IBSAL, Servicio de Medicina Interna-Unidad de Enfermedades Infecciosas, Salamanca, Spain., Bezerra JF; Escola Tecnica de Saúde, Laboratorio de Vigilancia Molecular Aplicada, Brasilia, Brazil., Bezerra MAC; Federal University of Pernambuco, Genetics Postgraduate Program, Recife, Brazil., Boix-Palop L; Hospital Universitario Mutua Terrassa, Barcelona, Spain., Brion M; Instituto de Investigación Sanitaria de Santiago (IDIS), Xenética Cardiovascular, Santiago de Compostela, Spain.; CIBERCV, ISCIII, Madrid, Spain., Brugada R; CIBERCV, ISCIII, Madrid, Spain.; Cardiovascular Genetics Center, Institut d'Investigació Biomèdica Girona (IDIBGI), Girona, Spain.; Medical Science Department, School of Medicine, University of Girona, Girona, Spain.; Hospital Josep Trueta, Cardiology Service, Girona, Spain., Bustos M; Institute of Biomedicine of Seville (IBiS), Consejo Superior de Investigaciones Científicas (CSIC)- University of Seville- Virgen del Rocio University Hospital, Seville, Spain., Calderón EJ; Institute of Biomedicine of Seville (IBiS), Consejo Superior de Investigaciones Científicas (CSIC)- University of Seville- Virgen del Rocio University Hospital, Seville, Spain.; Departamento de Medicina, Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Seville, Spain.; CIBERESP, ISCIII, Madrid, Spain., Carbonell C; Hospital Universitario de Salamanca-IBSAL, Servicio de Medicina Interna, Salamanca, Spain.; Universidad de Salamanca, Salamanca, Spain., Castano L; CIBERER, ISCIII, Madrid, Spain.; Biocruces Bizkai HRI, Bizkaia, Spain.; Osakidetza, Cruces University Hospital, Bizkaia, Spain.; Centre for Biomedical Network Research on Diabetes and Metabolic Associated Diseases (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain.; University of Pais Vasco, UPV/EHU, Bizkaia, Spain., Castelao JE; Oncology and Genetics Unit, Instituto de Investigacion Sanitaria Galicia Sur, Xerencia de Xestion Integrada de Vigo-Servizo Galego de Saúde, Vigo, Spain., Conde-Vicente R; Hospital Universitario Río Hortega, Valladolid, Spain., Cordero-Lorenzana ML; Servicio de Medicina intensiva, Complejo Hospitalario Universitario de A Coruña (CHUAC), Sistema Galego de Saúde (SERGAS), A Coruña, Spain., Cortes-Sanchez JL; Tecnológico de Monterrey, Monterrey, Mexico.; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Magdeburg, Germany., Corton M; CIBERER, ISCIII, Madrid, Spain.; Department of Genetics & Genomics, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain., Darnaude MT; Hospital Universitario Mostoles, Unidad de Genética, Madrid, Spain., De Martino-Rodríguez A; Instituto Aragonés de Ciencias de la Salud (IACS), Zaragoza, Spain.; Instituto Investigación Sanitaria Aragón (IIS-Aragon), Zaragoza, Spain., Del Campo-Pérez V; Preventive Medicine Department, Instituto de Investigacion Sanitaria Galicia Sur, Xerencia de Xestion Integrada de Vigo-Servizo Galego de Saúde, Vigo, Spain., de Bustamante AD; Hospital Universitario Mostoles, Unidad de Genética, Madrid, Spain., Domínguez-Garrido E; Unidad Diagnóstico Molecular, Fundación Rioja Salud, La Rioja, Spain., Eirós R; Hospital Universitario de Salamanca-IBSAL, Servicio de Cardiología, Salamanca, Spain., Fariñas MC; IDIVAL, Cantabria, Spain.; Hospital U M Valdecilla, Cantabria, Spain.; Universidad de Cantabria, Cantabria, Spain., Fernandez-Nestosa MJ; Universidad Nacional de Asunción, Facultad de Politécnica, Paraguay, United States., Fernández-Robelo U; Urgencias Hospitalarias, Complejo Hospitalario Universitario de A Coruña (CHUAC), Sistema Galego de Saúde (SERGAS), A Coruña, Spain., Fernández-Rodríguez A; CIBERINFEC, ISCIII, Madrid, Spain.; Unidad de Infección Viral e Inmunidad, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain., Fernández-Villa T; CIBERESP, ISCIII, Madrid, Spain.; Grupo de Investigación en Interacciones Gen-Ambiente y Salud (GIIGAS) - Instituto de Biomedicina (IBIOMED), Universidad de León, León, Spain., Gago-Dominguez M; Fundación Pública Galega de Medicina Xenómica, Sistema Galego de Saúde (SERGAS), Santiago de Compostela, Spain.; IDIS, Seongnam, Republic of Korea., Gil-Fournier B; Hospital Universitario de Getafe, Servicio de Genética, Madrid, Spain., Gómez-Arrue J; Instituto Aragonés de Ciencias de la Salud (IACS), Zaragoza, Spain.; Instituto Investigación Sanitaria Aragón (IIS-Aragon), Zaragoza, Spain., Álvarez BG; Instituto Aragonés de Ciencias de la Salud (IACS), Zaragoza, Spain.; Instituto Investigación Sanitaria Aragón (IIS-Aragon), Zaragoza, Spain., Bernaldo de Quirós FG; Ministerio de Salud Ciudad de Buenos Aires, Buenos Aires, Argentina., González-Neira A; Spanish National Cancer Research Centre, Human Genotyping-CEGEN Unit, Madrid, Spain., González-Peñas J; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón (IiSGM), Madrid, Spain.; School of Medicine, Universidad Complutense, Madrid, Spain.; Centre for Biomedical Network Research on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain., Gutiérrez-Bautista JF; Hospital Universitario Virgen de las Nieves, Servicio de Análisis Clínicos e Inmunología, Granada, Spain., Herrero MJ; IIS La Fe, Plataforma de Farmacogenética, Valencia, Spain.; Universidad de Valencia, Departamento de Farmacología, Valencia, Spain., Herrero-Gonzalez A; Data Analysis Department, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain., Jimenez-Sousa MA; CIBERINFEC, ISCIII, Madrid, Spain.; Unidad de Infección Viral e Inmunidad, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain., Lattig MC; Universidad de los Andes, Facultad de Ciencias, Bogotá, Colombia.; SIGEN Alianza Universidad de los Andes - Fundación Santa Fe de Bogotá, Bogotá, Colombia., Borja AL; Hospital General de Segovia, Medicina Intensiva, Segovia, Spain., Lopez-Rodriguez R; CIBERER, ISCIII, Madrid, Spain.; Department of Genetics & Genomics, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain.; Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte, Spain., Mancebo E; Hospital Universitario 12 de Octubre, Department of Immunology, Madrid, Spain.; Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Transplant Immunology and Immunodeficiencies Group, Madrid, Spain., Martín-López C; Hospital General de Segovia, Medicina Intensiva, Segovia, Spain., Martín V; CIBERESP, ISCIII, Madrid, Spain.; Grupo de Investigación en Interacciones Gen-Ambiente y Salud (GIIGAS) - Instituto de Biomedicina (IBIOMED), Universidad de León, León, Spain., Martinez-Nieto O; SIGEN Alianza Universidad de los Andes - Fundación Santa Fe de Bogotá, Bogotá, Colombia.; Fundación Santa Fe de Bogota, Departamento Patologia y Laboratorios, Bogotá, Colombia., Martinez-Lopez I; Unidad de Genética y Genómica Islas Baleares, Islas Baleares, Spain.; Hospital Universitario Son Espases, Unidad de Diagnóstico Molecular y Genética Clínica, Islas Baleares, Spain., Martinez-Resendez MF; Tecnológico de Monterrey, Monterrey, Mexico., Martinez-Perez A; Genomics of Complex Diseases Unit, Research Institute of Hospital de la Santa Creu i Sant Pau, IIB Sant Pau, Barcelona, Spain., Mazzeu JF; Universidade de Brasília, Faculdade de Medicina, Brasília, Brazil.; Programa de Pós-Graduação em Ciências Médicas (UnB), Brasília, Brazil.; Programa de Pós-Graduação em Ciencias da Saude (UnB), Brazila, Brazil., Macías EM; Hospital El Bierzo, Unidad Cuidados Intensivos, León, Spain., Minguez P; CIBERER, ISCIII, Madrid, Spain.; Department of Genetics & Genomics, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain., Cuerda VM; Hospital Universitario Mostoles, Medicina Interna, Madrid, Spai, Spain.; Universidad Francisco de Vitoria, Madrid, Spain., Oliveira SF; Programa de Pós-Graduação em Ciencias da Saude (UnB), Brazila, Brazil.; Departamento de Genética e Morfologia, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, Brazil.; Programa de Pós-Graduação em Biologia Animal (UnB), Brasília, Brazil.; Programa de Pós-Graduação Profissional em Ensino de Biologia (UnB), Brasília, Brazil., Ortega-Paino E; Spanish National Cancer Research Centre, CNIO Biobank, Madrid, Spain., Parellada M; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón (IiSGM), Madrid, Spain.; School of Medicine, Universidad Complutense, Madrid, Spain.; Centre for Biomedical Network Research on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain., Paz-Artal E; Hospital Universitario 12 de Octubre, Department of Immunology, Madrid, Spain.; Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Transplant Immunology and Immunodeficiencies Group, Madrid, Spain.; Universidad Complutense de Madrid, Department of Immunology, Ophthalmology and ENT, Madrid, Spain., Santos NPC; Universidade Federal do Pará, Núcleo de Pesquisas em Oncologia, Belém, Brazil., Pérez-Matute P; Infectious Diseases, Microbiota and Metabolism Unit, CSIC Associated Unit, Center for Biomedical Research of La Rioja (CIBIR), Logroño, Spain., Perez P; Inditex, A Coruña, Corunna, Spain., Pérez-Tomás ME; Instituto Murciano de Investigación Biosanitaria (IMIB-Arrixaca), Murcia, Spain., Perucho T; GENYCA, Madrid, Spain., Pinsach-Abuin M; CIBERCV, ISCIII, Madrid, Spain.; Cardiovascular Genetics Center, Institut d'Investigació Biomèdica Girona (IDIBGI), Girona, Spain., Pita G; Spanish National Cancer Research Centre, Human Genotyping-CEGEN Unit, Madrid, Spain., Pompa-Mera EN; Instituto Mexicano del Seguro Social (IMSS), Centro Médico Nacional Siglo XXI, Unidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Mexico City, Mexico.; Instituto Mexicano del Seguro Social (IMSS), Centro Médico Nacional La Raza, Hospital de Infectología, Mexico City, Mexico., Porras-Hurtado GL; Clinica Comfamiliar Risaralda, Pereira, Colombia., Pujol A; CIBERER, ISCIII, Madrid, Spain.; Bellvitge Biomedical Research Institute (IDIBELL), Neurometabolic Diseases Laboratory, L'Hospitalet de Llobregat, Barcelona, Spain.; Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain., León SR; Hospital Universitario de Getafe, Servicio de Genética, Madrid, Spain., Resino S; CIBERINFEC, ISCIII, Madrid, Spain.; Unidad de Infección Viral e Inmunidad, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain., Fernandes MR; Universidade Federal do Pará, Núcleo de Pesquisas em Oncologia, Belém, Brazil.; Hospital Ophir Loyola, Departamento de Ensino e Pesquisa, Belém, Brazil., Rodríguez-Ruiz E; IDIS, Seongnam, Republic of Korea.; Unidad de Cuidados Intensivos, Hospital Clínico Universitario de Santiago (CHUS), Sistema Galego de Saúde (SERGAS), Santiago de Compostela, Spain., Rodriguez-Artalejo F; CIBERESP, ISCIII, Madrid, Spain.; Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain.; IdiPaz (Instituto de Investigación Sanitaria Hospital Universitario La Paz), Madrid, Spain.; IMDEA-Food Institute, CEI UAM+CSIC, Madrid, Spain., Rodriguez-Garcia JA; Complejo Asistencial Universitario de León, León, Spain., Ruiz-Cabello F; IDIS, Seongnam, Republic of Korea.; Instituto de Investigación Biosanitaria de Granada (ibs GRANADA), Granada, Spain.; Universidad de Granada, Departamento Bioquímica, Biología Molecular e Inmunología III, Granada, Spain., Ruiz-Hornillos J; Hospital Infanta Elena, Allergy Unit, Valdemoro, Madrid, Spain.; Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain.; Faculty of Medicine, Universidad Francisco de Vitoria, Madrid, Spain., Ryan P; CIBERINFEC, ISCIII, Madrid, Spain.; Hospital Universitario Infanta Leonor, Madrid, Spain.; Complutense University of Madrid, Madrid, Spain.; Gregorio Marañón Health Research Institute (IiSGM), Madrid, Spain., Soria JM; Genomics of Complex Diseases Unit, Research Institute of Hospital de la Santa Creu i Sant Pau, IIB Sant Pau, Barcelona, Spain., Souto JC; Haemostasis and Thrombosis Unit, Hospital de la Santa Creu i Sant Pau, IIB Sant Pau, Barcelona, Spain., Tamayo E; Hospital Clinico Universitario de Valladolid, Servicio de Anestesiologia y Reanimación, Valladolid, Spain.; Universidad de Valladolid, Departamento de Cirugía, Valladolid, Spain., Tamayo-Velasco A; Hospital Clinico Universitario de Valladolid, Servicio de Hematologia y Hemoterapia, Valladolid, Spain., Taracido-Fernandez JC; Data Analysis Department, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain., Teper A; Hospital de Niños Ricardo Gutierrez, Buenos Aires, Argentina., Torres-Tobar L; Fundación Universitaria de Ciencias de la Salud, Bogotá, Colombia., Urioste M; Spanish National Cancer Research Centre, Familial Cancer Clinical Unit, Madrid, Spain., Valencia-Ramos J; University Hospital of Burgos, Burgos, Spain., Yáñez Z; Universidad Simón Bolívar, Facultad de Ciencias de la Salud, Barranquilla, Colombia., Zarate R; Centro para el Desarrollo de la Investigación Científica, Asunción, Paraguay., de Rojas I; Centre for Biomedical Network Research on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Research Center and Memory clinic, ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain., Ruiz A; Centre for Biomedical Network Research on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Research Center and Memory clinic, ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain., Sánchez P; CIEN Foundation/Queen Sofia Foundation Alzheimer Center, Madrid, Spain., Real LM; Hospital Universitario de Valme, Unidad Clínica de Enfermedades Infecciosas y Microbiología, Sevilla, Spain., Guillen-Navarro E; Instituto Murciano de Investigación Biosanitaria (IMIB-Arrixaca), Murcia, Spain.; Sección Genética Médica - Servicio de Pediatría, Hospital Clínico Universitario Virgen de la Arrixaca, Servicio Murciano de Salud, Murcia, Spain.; Departamento Cirugía, Pediatría, Obstetricia y Ginecología, Facultad de Medicina, Universidad de Murcia (UMU), Murcia, Spain.; Grupo Clínico Vinculado, Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain., Ayuso C; CIBERER, ISCIII, Madrid, Spain.; Department of Genetics & Genomics, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain., Parra E; Department of Anthropology, University of Toronto at Mississauga, Mississauga, Canada., Riancho JA; CIBERER, ISCIII, Madrid, Spain.; IDIVAL, Cantabria, Spain.; Hospital U M Valdecilla, Cantabria, Spain.; Universidad de Cantabria, Cantabria, Spain., Rojas-Martinez A; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Mexico., Flores C; Genomics Division, Instituto Tecnológico y de Energías Renovables, Santa Cruz de Tenerife, Spain.; Research Unit, Hospital Universitario Nuestra Señora de Candelaria, Instituto de Investigación Sanitaria de Canarias, Santa Cruz de Tenerife, Spain.; Department of Clinical Sciences, University Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain.; Centre for Biomedical Network Research on Respiratory Diseases (CIBERES), Instituto de Salud Carlos III, Madrid, Spain., Lapunzina P; ERN-ITHACA-European Reference Network, Soria, Spain.; CIBERER, ISCIII, Madrid, Spain.; Instituto de Genética Médica y Molecular (INGEMM), Hospital Universitario La Paz IDIPAZ, Madrid, Spain., Carracedo Á; CIBERER, ISCIII, Madrid, Spain.; Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Fundación Pública Galega de Medicina Xenómica, Sistema Galego de Saúde (SERGAS), Santiago de Compostela, Spain.; IDIS, Seongnam, Republic of Korea.

Publikováno v: ELife [Elife] 2024 Oct 03; Vol. 13. Date of Electronic Publication: 2024 Oct 03.

Clinical Utility and Implementation of Pharmacogenomics for the Personalisation of Antipsychotic Treatments.

Autor: Hernandez M; PHAGEX Research Group, University Ramon Llull, 08022 Barcelona, Spain.; School of Health Sciences Blanquerna, University Ramon Llull, 08022 Barcelona, Spain., Cullell N; Fundació Docència i Recerca Mútua Terrassa, 08221 Terrassa, Spain.; Department of Neurology, Hospital Universitari Mútua Terrassa, 08221 Terrassa, Spain., Cendros M; EUGENOMIC Genómica y Farmacogenética, 08029 Barcelona, Spain., Serra-Llovich A; Fundació Docència i Recerca Mútua Terrassa, 08221 Terrassa, Spain., Arranz MJ; PHAGEX Research Group, University Ramon Llull, 08022 Barcelona, Spain.; Fundació Docència i Recerca Mútua Terrassa, 08221 Terrassa, Spain.

Publikováno v: Pharmaceutics [Pharmaceutics] 2024 Feb 07; Vol. 16 (2). Date of Electronic Publication: 2024 Feb 07.

Psychosis Endophenotypes: A Gene-Set-Specific Polygenic Risk Score Analysis.

Autor: Wang B; Department of Mental Health Neuroscience, Division of Psychiatry, University College London, London, UK.; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Irizar H; Department of Mental Health Neuroscience, Division of Psychiatry, University College London, London, UK.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Thygesen JH; Department of Mental Health Neuroscience, Division of Psychiatry, University College London, London, UK.; Institute of Health Informatics, University College London, London, UK., Zartaloudi E; Department of Mental Health Neuroscience, Division of Psychiatry, University College London, London, UK., Austin-Zimmerman I; Department of Mental Health Neuroscience, Division of Psychiatry, University College London, London, UK.; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Bhat A; Department of Mental Health Neuroscience, Division of Psychiatry, University College London, London, UK., Harju-Seppänen J; Department of Mental Health Neuroscience, Division of Psychiatry, University College London, London, UK., Pain O; Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Bass N; Department of Mental Health Neuroscience, Division of Psychiatry, University College London, London, UK., Gkofa V; Department of Mental Health Neuroscience, Division of Psychiatry, University College London, London, UK., Alizadeh BZ; University of Groningen, University Medical Center Groningen, University Center for Psychiatry, Rob Giel Research Center, Groningen, The Netherlands.; Department of Epidemiology, University Medical Center Groningen, Groningen, The Netherlands., van Amelsvoort T; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands., Arranz MJ; Fundació Docència i Recerca Mutua Terrassa, Terrassa, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Institut de Recerca Biomédica Sant Pau (IIB-Sant Pau), Barcelona, Spain., Bender S; Department of Child and Adolescent Psychiatry, Psychosomatic Medicine and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Cahn W; Department of Psychiatry, Brain Centre Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Altrecht, General Mental Health Care, Utrecht, The Netherlands., Stella Calafato M; Department of Mental Health Neuroscience, Division of Psychiatry, University College London, London, UK., Crespo-Facorro B; CIBERSAM, Centro Investigación Biomédica en Red Salud Mental, Sevilla, Spain.; Department of Psychiatry, University Hospital Virgen del Rocio, School of Medicine, University of Sevilla-IBiS, Sevilla, Spain., Di Forti M; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Giegling I; Comprehensive Centers for Clinical Neurosciences and Mental Health (C3NMH), Medical University of Vienna, Austria., de Haan L; Department of Psychiatry, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Arkin, Institute for Mental Health, Amsterdam, The Netherlands., Hall J; Neuroscience and Mental Health Innovation Institute, School of Medicine, Cardiff University, Hadyn Ellis Building, Mandy Road, Cardiff, UK., Hall MH; Psychosis Neurobiology Laboratory, Harvard Medical School, McLean Hospital, Belmont, MA, USA., van Haren N; Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Sophia's Children Hospital, Rotterdam, The Netherlands., Iyegbe C; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kahn RS; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kravariti E; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Lawrie SM; Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK., Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Luykx JJ; Department of Psychiatry, Brain Centre Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands., Mata I; Fundacion Argibide, Pamplona, Spain.; CIBERSAM, Centro Investigación Biomédica en Red Salud Mental, Madrid, Spain., McDonald C; The Centre for Neuroimaging & Cognitive Genomics (NICOG) and NCBES Galway Neuroscience Centre, University of Galway, Galway, Ireland., McIntosh AM; Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Murray RM; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Picchioni M; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; St Magnus Hospital, Surrey, UK., Powell J; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Prata DP; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciencias da Universidade de Lisboa, Portugal., Rujescu D; Department of Psychiatry, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Division of General Psychiatry, Medical University of Vienna, Austria., Rutten BPF; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands., Shaikh M; North East London Foundation Trust, London, UK.; Research Department of Clinical, Educational and Health Psychology, University College London, London, UK., Simons CJP; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands.; GGzE Institute for Mental Health Care, Eindhoven, The Netherlands., Toulopoulou T; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Interdisciplinary Program in Neuroscience, Aysel Sabuncu Brain Research Center, Bilkent University, Ankara, Türkiye.; National Magnetic Resonance Research Center (UMRAM), Bilkent University, Ankara, Türkiye.; Department of Psychology, Bilkent University, Ankara, Türkiye.; School of Medicine, Department of Psychiatry, National and Kapodistrian University of Athens, Athens, Greece.; Department of Psychiatry and Behavioral Health System, Icahn School of Medicine at Mount Sinai, New York, USA., Weisbrod M; Department of General Psychiatry, Center of Psychosocial Medicine, University of Heidelberg, Germany.; SRH Klinikum, Karlsbad-Langensteinbach, Germany., van Winkel R; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands.; KU Leuven, Department of Neuroscience, Research Group Psychiatry, Leuven, Belgium., Kuchenbaecker K; Department of Mental Health Neuroscience, Division of Psychiatry, University College London, London, UK.; UCL Genetics Institute, Division of Biosciences, University College London, London, UK., McQuillin A; Department of Mental Health Neuroscience, Division of Psychiatry, University College London, London, UK., Bramon E; Department of Mental Health Neuroscience, Division of Psychiatry, University College London, London, UK.; Institute of Cognitive Neuroscience, University College London, London, UK.

Publikováno v: Schizophrenia bulletin [Schizophr Bull] 2023 Nov 29; Vol. 49 (6), pp. 1625-1636.

Novel genes and sex differences in COVID-19 severity.

Autor: Cruz R; Centro Nacional de Genotipado (CEGEN), Universidade de Santiago de Compostela, 15706 Santiago de Compostela, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Instituto de Investigación Sanitaria de Santiago (IDIS), 15706 Santiago de Compostela, Spain.; Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CIMUS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain., Diz-de Almeida S; Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CIMUS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain., López de Heredia M; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain., Quintela I; Centro Nacional de Genotipado (CEGEN), Universidade de Santiago de Compostela, 15706 Santiago de Compostela, Spain., Ceballos FC; Unidad de Infección Viral e Inmunidad, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), 28220 Madrid, Spain., Pita G; Spanish National Cancer Research Centre, Human Genotyping-CEGEN Unit, 28029 Madrid, Spain., Lorenzo-Salazar JM; Genomics Division, Instituto Tecnológico y de Energías Renovables, 38600 Santa Cruz de Tenerife, Spain., González-Montelongo R; Genomics Division, Instituto Tecnológico y de Energías Renovables, 38600 Santa Cruz de Tenerife, Spain., Gago-Domínguez M; Fundación Pública Galega de Medicina Xenómica, Sistema Galego de Saúde (SERGAS), 15706 Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago (IDIS), 15706 Santiago de Compostela, Spain., Sevilla Porras M; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Instituto de Genética Médica y Molecular (INGEMM), Hospital Universitario La Paz-IDIPAZ, 28046 Madrid, Spain., Tenorio Castaño JA; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Instituto de Genética Médica y Molecular (INGEMM), Hospital Universitario La Paz-IDIPAZ, 28046 Madrid, Spain.; ERN-ITHACA-European Reference Network., Nevado J; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Instituto de Genética Médica y Molecular (INGEMM), Hospital Universitario La Paz-IDIPAZ, 28046 Madrid, Spain.; ERN-ITHACA-European Reference Network., Aguado JM; Unit of Infectious Diseases, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), 28041 Madrid, Spain.; Spanish Network for Research in Infectious Diseases (REIPI RD16/0016/0002), Instituto de Salud Carlos III, 28029 Madrid, Spain.; School of Medicine, Universidad Complutense, 28040 Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029 Madrid, Spain., Aguilar C; Hospital General Santa Bárbara de Soria, 42005 Soria, Spain., Aguilera-Albesa S; Pediatric Neurology Unit, Department of Pediatrics, Navarra Health Service Hospital, 31008 Pamplona, Spain.; Navarra Health Service, NavarraBioMed Research Group, 31008 Pamplona, Spain., Almadana V; Hospital Universitario Virgen Macarena, Neumología, 41009 Seville, Spain., Almoguera B; Department of Genetics & Genomics, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), 28040 Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain., Alvarez N; Spanish National Cancer Research Centre, Human Genotyping-CEGEN Unit, 28029 Madrid, Spain., Andreu-Bernabeu Á; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón (IiSGM), 28007 Madrid, Spain.; School of Medicine, Universidad Complutense, 28040 Madrid, Spain., Arana-Arri E; Biocruces Bizkai HRI, 48903 Barakaldo, Bizkaia, Spain.; Cruces University Hospital, Osakidetza, 48903 Barakaldo, Bizkaia, Spain., Arango C; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón (IiSGM), 28007 Madrid, Spain.; Centre for Biomedical Network Research on Mental Health (CIBERSAM), Instituto de Salud Carlos III, 28029 Madrid, Spain.; School of Medicine, Universidad Complutense, 28040 Madrid, Spain., Arranz MJ; Fundació Docència I Recerca Mutua Terrassa, 08221 Terrassa, Spain., Artiga MJ; Spanish National Cancer Research Center, CNIO Biobank, 28029 Madrid, Spain., Baptista-Rosas RC; Hospital General de Occidente, 45170 Zapopan, Jalisco, Mexico.; Centro Universitario de Tonalá, Universidad de Guadalajara, 45425 Tonalá, Jalisco, Mexico.; Centro de Investigación Multidisciplinario en Salud, Universidad de Guadalajara, 45425 Tonalá, Jalisco, Mexico., Barreda-Sánchez M; Instituto Murciano de Investigación Biosanitaria (IMIB-Arrixaca), 30120 Murcia, Spain.; Universidad Católica San Antonio de Murcia (UCAM), 30120 Murcia, Spain., Belhassen-Garcia M; Hospital Universitario de Salamanca-IBSAL, Servicio de Medicina Interna-Unidad de Enfermedades Infecciosas, 37007 Salamanca, Spain.; Universidad de Salamanca, 37007 Salamanca, Spain., Bezerra JF; Escola Tecnica de Saúde, Laboratorio de Vigilancia Molecular Aplicada, 68515-000 Pará, Brazil., Bezerra MAC; Federal University of Pernambuco, Genetics Postgraduate Program, Recife 50670-907, PE, Brazil., Boix-Palop L; Hospital Universitario Mutua Terrassa, 08221 Terrassa, Spain., Brion M; Instituto de Investigación Sanitaria de Santiago (IDIS), Xenética Cardiovascular, 15706 Santiago de Compostela, Spain.; Centre for Biomedical Network Research on Cardiovascular Diseases (CIBERCV), Instituto de Salud Carlos III, 28029 Madrid, Spain., Brugada R; Cardiovascular Genetics Center, Institut d'Investigació Biomèdica Girona (IDIBGI), 17190 Girona, Spain.; Medical Science Department, School of Medicine, University of Girona, 17190 Girona, Spain.; Centre for Biomedical Network Research on Cardiovascular Diseases (CIBERCV), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Hospital Josep Trueta, Cardiology Service, 17190 Girona, Spain., Bustos M; Institute of Biomedicine of Seville (IBiS), Consejo Superior de Investigaciones Científicas (CSIC)- University of Seville- Virgen del Rocio University Hospital, 41013 Seville, Spain., Calderón EJ; Departemento de Medicina, Hospital Universitario Virgen del Rocío, Universidad de Sevilla, 41013 Seville, Spain.; Centre for Biomedical Network Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Instituto de Biomedicina de Sevilla, 41013 Seville, Spain., Carbonell C; Hospital Universitario de Salamanca-IBSAL, Servicio de Medicina Interna, 37007 Salamanca, Spain.; Universidad de Salamanca, 37007 Salamanca, Spain., Castano L; Biocruces Bizkai HRI, 48903 Barakaldo, Bizkaia, Spain.; Osakidetza, Cruces University Hospital, 48903 Barakaldo, Bizkaia, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Centre for Biomedical Network Research on Diabetes and Metabolic Associated Diseases (CIBERDEM), Instituto de Salud Carlos III, 28029 Madrid, Spain.; University of Pais Vasco, UPV/EHU, 48903 Bizkaia, Spain., Castelao JE; Oncology and Genetics Unit, Instituto de Investigacion Sanitaria Galicia Sur, Xerencia de Xestion Integrada de Vigo-Servizo Galego de Saúde, 36312 Vigo, Spain., Conde-Vicente R; Hospital Universitario Río Hortega, 47012 Valladolid, Spain., Cordero-Lorenzana ML; Servicio de Medicina intensiva, Complejo Hospitalario Universitario de A Coruña (CHUAC), Sistema Galego de Saúde (SERGAS), 15009 A Coruña, Spain., Cortes-Sanchez JL; Tecnológico de Monterrey, 64718 Monterrey, Mexico.; Otto von Guericke University, Departament of Microgravity and Translational Regenerative Medicine, 39106 Magdeburg, Germany., Corton M; Department of Genetics & Genomics, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), 28040 Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain., Darnaude MT; Hospital Universitario Mostoles, Unidad de Genética, 28935 Madrid, Spain., De Martino-Rodríguez A; Instituto Aragonés de Ciencias de la Salud (IACS), 50009 Zaragoza, Spain.; Instituto Investigación Sanitaria Aragón (IIS-Aragon), 50009 Zaragoza, Spain., Del Campo-Pérez V; Preventive Medicine Department, Instituto de Investigacion Sanitaria Galicia Sur, Xerencia de Xestion Integrada de Vigo-Servizo Galego de Saúde, 36312 Vigo, Spain., Diaz de Bustamante A; Hospital Universitario Mostoles, Unidad de Genética, 28935 Madrid, Spain., Domínguez-Garrido E; Unidad Diagnóstico Molecular. Fundación Rioja Salud, 26006 La Rioja, Spain., Luchessi AD; Universidade Federal do Rio Grande do Norte, Departamento de Analises Clinicas e Toxicologicas, 59012-570 Natal, Brazil., Eiros R; Hospital Universitario de Salamanca-IBSAL, Servicio de Cardiología, 37007 Salamanca, Spain., Estigarribia Sanabria GM; Instituto Regional de Investigación en Salud-Universidad Nacional de Caaguazú, HH36+J3Q Caaguazú, Paraguay., Carmen Fariñas M; IDIVAL, 39008 Cantabria, Spain.; Universidad de Cantabria, 39008 Cantabria, Spain.; Hospital U M Valdecilla, 39008 Cantabria, Spain., Fernández-Robelo U; Urgencias Hospitalarias, Complejo Hospitalario Universitario de A Coruña (CHUAC), Sistema Galego de Saúde (SERGAS), 15009 A Coruña, Spain., Fernández-Rodríguez A; Unidad de Infección Viral e Inmunidad, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), 28220 Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029 Madrid, Spain., Fernández-Villa T; Grupo de Investigación en Interacciones Gen-Ambiente y Salud (GIIGAS) - Instituto de Biomedicina (IBIOMED), Universidad de León, 24071 León, Spain., Gil-Fournier B; Hospital Universitario de Getafe, Servicio de Genética, 28905 Madrid, Spain., Gómez-Arrue J; Instituto Aragonés de Ciencias de la Salud (IACS), 50009 Zaragoza, Spain.; Instituto Investigación Sanitaria Aragón (IIS-Aragon), 50009 Zaragoza, Spain., González Álvarez B; Instituto Aragonés de Ciencias de la Salud (IACS), 50009 Zaragoza, Spain.; Instituto Investigación Sanitaria Aragón (IIS-Aragon), 50009 Zaragoza, Spain., Gonzalez Bernaldo de Quirós F; Ministerio de Salud Ciudad de Buenos Aires, Buenos Aires C1425EFD CABA, Argentina., González-Peñas J; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón (IiSGM), 28007 Madrid, Spain.; School of Medicine, Universidad Complutense, 28040 Madrid, Spain.; Centre for Biomedical Network Research on Mental Health (CIBERSAM), Instituto de Salud Carlos III, 28029 Madrid, Spain., Gutiérrez-Bautista JF; Hospital Universitario Virgen de las Nieves, Servicio de Análisis Clínicos e Inmunología, 18014 Granada, Spain., Herrero MJ; IIS La Fe, Plataforma de Farmacogenética, 46026 Valencia, Spain.; Universidad de Valencia, Departamento de Farmacología, 46010 Valencia, Spain., Herrero-Gonzalez A; Data Analysis Department, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), 28040 Madrid, Spain., Jimenez-Sousa MA; Unidad de Infección Viral e Inmunidad, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), 28220 Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029 Madrid, Spain., Lattig MC; Universidad de los Andes, Facultad de Ciencias, Bogotá 111711, Colombia.; SIGEN Alianza Universidad de los Andes - Fundación Santa Fe de Bogotá, Bogotá 111711, Clombia., Liger Borja A; Hospital General de Segovia, Medicina Intensiva, 40002 Segovia, Spain., Lopez-Rodriguez R; Department of Genetics & Genomics, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), 28040 Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain., Mancebo E; Hospital Universitario 12 de Octubre, Department of Immunology, 28041 Madrid, Spain.; Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Transplant Immunology and Immunodeficiencies Group, 28041 Madrid, Spain., Martín-López C; Hospital General de Segovia, Medicina Intensiva, 40002 Segovia, Spain., Martín V; Instituto de Biomedicina (IBIOMED), Universidad de León, 24071 León, Spain.; Centre for Biomedical Network Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, 28029 Madrid, Spain., Martinez-Nieto O; Fundación Santa Fe de Bogota, Departamento Patologia y Laboratorios, Bogotá 111711, Colombia.; SIGEN Alianza Universidad de los Andes - Fundación Santa Fe de Bogotá, Bogotá 111711, Clombia., Martinez-Lopez I; Unidad de Genética y Genómica Islas Baleares, 07120 Islas Baleares, Spain.; Hospital Universitario Son Espases, Unidad de Diagnóstico Molecular y Genética Clínica, 07120 Islas Baleares, Spain., Martinez-Resendez MF; Tecnológico de Monterrey, 64718 Monterrey, Mexico., Martinez-Perez A; Genomics of Complex Diseases Unit, Research Institute of Hospital de la Santa Creu i Sant Pau, IIB Sant Pau, 08041 Barcelona, Spain., Mazzeu JF; Faculdade de Medicina, Universidade de Brasília, Brasilia 70910-900, Brazil.; Programa de Pós-Graduação em Ciências Médicas, Universidade de Brasília, Brasilia 70910-900, Brazil.; Programa de Pós-Graduação em Ciências da Saúde, Universidade de Brasília, Brasilia 70910-900, Brazil., Merayo Macías E; Hospital El Bierzo, Unidad Cuidados Intensivos, 24404 León, Spain., Minguez P; Department of Genetics & Genomics, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), 28040 Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain., Moreno Cuerda V; Hospital Universitario Mostoles, Medicina Interna, 28935 Madrid, Spain.; Universidad Francisco de Vitoria, 28223 Madrid, Spain., Silbiger VN; Universidade Federal do Rio Grande do Norte, Departamento de Analises Clinicas e Toxicologicas, 59012-570 Natal, Brazil., Oliveira SF; Faculdade de Medicina, Universidade de Brasília, Brasilia 70910-900, Brazil.; Programa de Pós-Graduação em Biologia Animal, Universidade de Brasília, Brasília 70910-900, Brazil.; Programa de Pós-Graduação Profissional em Ensino de Biologia, Universidade de Brasília, Brasília 70910-900, Brazil.; Programa de Pós-Graduação Profissional em Ensino de Biologia (UnB), Universidade de Brasília, Brasília 70910-900, Brazil.; Programa de Pós-Graduação em Ciências Médicas, Universidade de Brasília, Brasília 70910-900, Brazil., Ortega-Paino E; Spanish National Cancer Research Center, CNIO Biobank, 28029 Madrid, Spain., Parellada M; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón (IiSGM), 28007 Madrid, Spain.; Centre for Biomedical Network Research on Mental Health (CIBERSAM), Instituto de Salud Carlos III, 28029 Madrid, Spain.; School of Medicine, Universidad Complutense, 28040 Madrid, Spain., Paz-Artal E; Hospital Universitario 12 de Octubre, Department of Immunology, 28041 Madrid, Spain.; Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Transplant Immunology and Immunodeficiencies Group, 28041 Madrid, Spain.; Universidad Complutense de Madrid, Department of Immunology, Ophthalmology and ENT, 28040 Madrid, Spain., Santos NPC; Universidade Federal do Pará, Núcleo de Pesquisas em Oncologia, Belém, Pará 66075-110, Brazil., Pérez-Matute P; Infectious Diseases, Microbiota and Metabolism Unit, Center for Biomedical Research of La Rioja (CIBIR), 26006 Logroño, Spain., Perez P; Inditex, 15141 A Coruña, Spain., Pérez-Tomás ME; Instituto Murciano de Investigación Biosanitaria (IMIB-Arrixaca), 30120 Murcia, Spain., Perucho T; GENYCA, 28220 Madrid, Spain., Pinsach-Abuin ML; Cardiovascular Genetics Center, Institut d'Investigació Biomèdica Girona (IDIBGI), 17190 Girona, Spain.; Centre for Biomedical Network Research on Cardiovascular Diseases (CIBERCV), Instituto de Salud Carlos III, 28029 Madrid, Spain., Pompa-Mera EN; Instituto Mexicano del Seguro Social (IMSS), Centro Médico Nacional Siglo XXI, Unidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Mexico City 02990, Mexico., Porras-Hurtado GL; Clinica Comfamiliar Risaralda, 660003 Pereira, Colombia., Pujol A; Bellvitge Biomedical Research Institute (IDIBELL), Neurometabolic Diseases Laboratory, 08908 L'Hospitalet de Llobregat, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Catalan Institution of Research and Advanced Studies (ICREA), 08010 Barcelona, Spain., Ramiro León S; Hospital Universitario de Getafe, Servicio de Genética, 28905 Madrid, Spain., Resino S; Unidad de Infección Viral e Inmunidad, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), 28220 Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029 Madrid, Spain., Fernandes MR; Universidade Federal do Pará, Núcleo de Pesquisas em Oncologia, Belém, Pará 66075-110, Brazil.; Hospital Ophir Loyola, Departamento de Ensino e Pesquisa, Belém, Pará 66063-240, Brazil., Rodríguez-Ruiz E; Unidad de Cuidados Intensivos, Hospital Clínico Universitario de Santiago (CHUS), Sistema Galego de Saúde (SERGAS), 15706 Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago (IDIS), 15706 Santiago de Compostela, Spain., Rodriguez-Artalejo F; Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid, 28049 Madrid, Spain.; IdiPaz (Instituto de Investigación Sanitaria Hospital Universitario La Paz), 28046 Madrid, Spain.; Centre for Biomedical Network Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, 28029 Madrid, Spain.; IMDEA-Food Institute, CEI UAM+CSIC, 28049 Madrid, Spain., Rodriguez-Garcia JA; Complejo Asistencial Universitario de León, 24071 León, Spain., Ruiz Cabello F; Hospital Universitario Virgen de las Nieves, Servicio de Análisis Clínicos e Inmunología, 18014 Granada, Spain.; Instituto de Investigación Biosanitaria de Granada (ibs GRANADA), 18012 Granada, Spain.; Universidad de Granada, Departamento Bioquímica, Biología Molecular e Inmunología III, 18071 Granada, Spain., Ruiz-Hornillos J; Hospital Infanta Elena, Allergy Unit, Valdemoro, 28342 Madrid, Spain.; Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), 28040 Madrid, Spain.; Faculty of Medicine, Universidad Francisco de Vitoria, 28223 Madrid, Spain., Ryan P; Hospital Universitario Infanta Leonor, 28031 Madrid, Spain.; Complutense University of Madrid, 28040 Madrid, Spain.; Gregorio Marañón Health Research Institute (IiSGM), 28007 Madrid, Spain., Soria JM; Genomics of Complex Diseases Unit, Research Institute of Hospital de la Santa Creu i Sant Pau, IIB Sant Pau, 08041 Barcelona, Spain., Souto JC; Haemostasis and Thrombosis Unit, Hospital de la Santa Creu i Sant Pau, IIB Sant Pau, 08041 Barcelona, Spain., Tamayo E; Hospital Clinico Universitario de Valladolid, Servicio de Anestesiologia y Reanimación, 47003 Valladolid, Spain.; Universidad de Valladolid, Departamento de Cirugía, 47005 Valladolid, Spain., Tamayo-Velasco A; Hospital Clinico Universitario de Valladolid, Servicio de Hematologia y Hemoterapia, 47003 Valladolid, Spain., Taracido-Fernandez JC; Data Analysis Department, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), 28040 Madrid, Spain., Teper A; Hospital de Niños Ricardo Gutierrez, Buenos Aires C1425EFD CABA, Argentina., Torres-Tobar L; Fundación Universitaria de Ciencias de la Salud, 113827 Bogotá, Colombia., Urioste M; Spanish National Cancer Research Centre, Familial Cancer Clinical Unit, 28029 Madrid, Spain., Valencia-Ramos J; University Hospital of Burgos, 09006 Burgos, Spain., Yáñez Z; Universidad Simón Bolívar, Facultad de Ciencias de la Salud, 080002 Barranquilla, Colombia., Zarate R; Centro para el Desarrollo de la Investigación Científica, 1255 Asunción, Paraguay., Nakanishi T; Institute for Molecular Medicine Finland (FIMM), 00014 Univerisity of Helsinki, Finland.; McGill University, Department of Human Genetics, H3A 0G4 Montréal, Québec, Canada.; Lady Davis Institute, Jewish General Hospital, McGill University, H3T 1E2 Montréal, Québec, Canada.; Kyoto-McGill International Collaborative School in Genomic Medicine, Graduate School of Medicine, Kyoto University, 606-8501 Kyoto, Japan.; Research Fellow, Japan Society for the Promotion of Science, 102-0083 Tokyo, Japan., Pigazzini S; University of Milano-Bicocca, 20126 Milano, Italy.; Institute for Molecular Medicine Finland, Univerisity of Helsinki, 00014 Helsinki, Finland., Degenhardt F; Institute of Clinical Molecular Biology, Christian-Albrechts-University, 24118 Kiel, Germany.; University Hospital Schleswig-Holstein, Campus Kiel, 24118 Kiel, Germany., Butler-Laporte G; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, H3A 0G4 Montréal, Québec, Canada.; Lady Davis Institute, Jewish General Hospital, McGill University, H3T 1E2 Montréal, Québec, Canada., Maya-Miles D; Digestive Diseases Unit, Virgen del Rocio University Hospital, Institute of Biomedicine of Seville, University of Seville, 41103 Seville, Spain.; Centre for Biomedical Network Research on Hepatic and Digestive Diseases (CIBEREHD), Instituto de Salud Carlos III, 28029 Madrid, Spain., Bujanda L; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital, University of the Basque Country (UPV/EHU), 20014 San Sebastian, Spain.; Centre for Biomedical Network Research on Hepatic and Digestive Diseases (CIBEREHD), Instituto de Salud Carlos III, 28029 Madrid, Spain., Bouysran Y; Centre de Génétique Humaine, Hôpital Erasme, Université Libre de Bruxelles, 1070 Brussels, Belgium., Palom A; Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, 08035 Barcelona, Spain.; Universitat Autònoma de Barcelona, Departament de Medicina, Bellatera, 08193 Barcelona, Spain.; Vall d'Hebron Institut de Recerca (VHIR), Liver Diseases, 08035 Barcelona, Spain., Ellinghaus D; Novo Nordisk Foundation Center for Protein Research, Disease Systems Biology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.; Institute of Clinical Molecular Biology, Christian-Albrechts-University, 24118 Kiel, Germany., Martínez-Bueno M; GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government, 18016 Granada, Spain., Rolker S; Institute of Human Genetics, University Hospital Bonn, Medical Faculty University of Bonn, 53127 Bonn, Germany., Amitrano S; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, 53100 Siena, Italy., Roade L; Centre for Biomedical Network Research on Hepatic and Digestive Diseases (CIBEREHD), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, 08035 Barcelona, Spain.; Universitat Autònoma de Barcelona, Departament de Medicina, Bellatera, 08193 Barcelona, Spain., Fava F; University of Siena, Medical Genetics, 53100 Siena, Italy.; Azienda Ospedaliero-Universitaria Senese, Genetica Medica, 53100 Siena, Italy.; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy., Spinner CD; Technical University of Munich, School of Medicine, University Hospital rechts der Isar, Department of Internal Medicine II, 80333 Munich, Germany., Prati D; Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, 20126 Milano, Italy., Bernardo D; Mucosal Immunology Lab, Unidad de Excelencia del Instituto de Biomedicina y Genética Molecular (IBGM, Universidad de Valladolid-CSIC), 47005 Valladolid, Spain.; Centre for Biomedical Network Research on Hepatic and Digestive Diseases (CIBEREHD), Instituto de Salud Carlos III, 28029 Madrid, Spain., Garcia F; Hospital Universitario Clinico San Cecilio, 18016 Granada, Spain.; Instituto de Investigación Ibs, Granada, 18012 Granada, Spain., Darcis G; University of Liege. GIGA-Insitute, B- 4000 Liege, Belgium.; Liege University Hospital (CHU of Liege), B- 4000 Liege, Belgium., Fernández-Cadenas I; Biomedical Research Institute Sant Pau (IIB Sant Pau), Stroke Pharmacogenomics and Genetics Group, 08041 Barcelona, Spain., Holter JC; Oslo University Hospital, Department of Microbiology, 0424 Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, 0424 Oslo, Norway., Banales JM; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital, University of the Basque Country (UPV/EHU), Ikerbasque, 20014 San Sebastian, Spain.; Centre for Biomedical Network Research on Hepatic and Digestive Diseases (CIBEREHD), Instituto de Salud Carlos III, 28029 Madrid, Spain., Frithiof R; Department of Surgical Sciences, Anaesthesiology and Intensive Care Medicine, Uppsala University, 751 05 Uppsala, Sweden., Duga S; Humanitas University, Department of Biomedical Sciences, 20089 Milan, Italy.; IRCCS Humanitas Research Hospital, Rozzano, 20089 Milan, Italy., Asselta R; Humanitas University, Department of Biomedical Sciences, 20089 Milan, Italy.; IRCCS Humanitas Research Hospital, Rozzano, 20089 Milan, Italy., Pereira AC; Heart Institute (InCor)/University of Sao Paulo Medical School, 05508-070 Sao Paulo, Brazil., Romero-Gómez M; Digestive Diseases Unit, Virgen del Rocio University Hospital, Institute of Biomedicine of Seville, University of Seville, 41103 Seville, Spain.; Centre for Biomedical Network Research on Hepatic and Digestive Diseases (CIBEREHD), Instituto de Salud Carlos III, 28029 Madrid, Spain., Nafría-Jiménez B; Osakidetza Basque Health Service, Donostialdea Integrated Health Organisation, Clinical Biochemistry Department, 20006 San Sebastian, Spain., Hov JR; Norwegian PSC Research Center and Section of Gastroenterology, Dept Transplantation Medicine, Oslo University Hospital, 0424 Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, 0424 Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital, 0424 Oslo, Norway., Migeotte I; Fonds de la Recherche Scientifique (FNRS), B - 1000 Brussels.; Centre de Génétique Humaine, Hôpital Erasme, Université Libre de Bruxelles, 1070 Brussels, Belgium., Renieri A; University of Siena, Medical Genetics, 53100 Siena, Italy.; Azienda Ospedaliero-Universitaria Senese, Genetica Medica, 53100 Siena, Italy.; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy., Planas AM; Institute for Biomedical Research of Barcelona (IIBB), National Spanish Research Council (CSIC), 08028 Barcelona, Spain.; Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Ludwig KU; Institute of Human Genetics, University Hospital Bonn, Medical Faculty University of Bonn, 53127 Bonn, Germany., Buti M; Centre for Biomedical Network Research on Hepatic and Digestive Diseases (CIBEREHD), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, 08035 Barcelona, Spain.; Universitat Autònoma de Barcelona, Departament de Medicina, Bellatera, 08193 Barcelona, Spain., Rahmouni S; University of Liege. GIGA-Insitute, B- 4000 Liege, Belgium., Alarcón-Riquelme ME; GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government, 18016 Granada, Spain.; Institute for Environmental Medicine, Karolinska Institutet, 171 65 Solna, Sweden., Schulte EC; Institute of Virology, Technical University Munich/Helmholtz Zentrum München, D-85764 Munich, Germany.; Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich University, 80539 Munich, Germany.; Department of Psychiatry, University Hospital, LMU Munich University, 80539 Munich, Germany., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University, 24118 Kiel, Germany.; University Hospital Schleswig-Holstein, Campus Kiel, 24118 Kiel, Germany., Karlsen TH; Norwegian PSC Research Center and Section of Gastroenterology, Dept Transplantation Medicine, Oslo University Hospital, 0424 Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, 0424 Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital, 0318 Oslo, Norway., Valenti L; Università degli Studi di Milano, Department of Pathopgysiology and Transplantation, 20126 Milano, Italy.; Department of Transfusion Medicine and Hematology, Precision Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy., Zeberg H; Karolinska Institutet, Department of Neuroscience, 171 77 Stockholm, Sweden.; Max-Planck Institute for Evolutionary Anthropology, 04103 Leipzig, Germany., Richards B; Department of Human Genetics, Epidemiology, Biostatistics and Occupational Health, McGill University, H3A 0G4 Montréal, Québec, Canada.; Lady Davis Institute, Jewish General Hospital, McGill University, H3T 1E2 Montréal, Québec, Canada.; King's College London, Department of Twin Research, London, WC2R 2LS, United Kingdom., Ganna A; Institute for Molecular Medicine Finland, Univerisity of Helsinki, 00014 Helsinki, Finland.; Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Boada M; Research Center and Memory clinic, ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08028 Barcelona, Spain.; Centre for Biomedical Network Research on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, 28029 Madrid, Spain., de Rojas I; Research Center and Memory clinic, ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08028 Barcelona, Spain.; Centre for Biomedical Network Research on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, 28029 Madrid, Spain., Ruiz A; Research Center and Memory clinic, ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, 08028 Barcelona, Spain.; Centre for Biomedical Network Research on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, 28029 Madrid, Spain., Sánchez-Juan P; CIEN Foundation/Queen Sofia Foundation Alzheimer Center, 28031 Madrid, Spain., Real LM; Hospital Universitario de Valme, Unidad Clínica de Enfermedades Infecciosas y Microbiología, 41014 Sevilla, Spain., Guillen-Navarro E; Instituto Murciano de Investigación Biosanitaria (IMIB-Arrixaca), 30120 Murcia, Spain.; Sección Genética Médica - Servicio de Pediatría, Hospital Clínico Universitario Virgen de la Arrixaca, Servicio Murciano de Salud, 30120 Murcia, Spain.; Departamento Cirugía, Pediatría, Obstetricia y Ginecología, Facultad de Medicina, Universidad de Murcia (UMU), 30100 Murcia, Spain.; Grupo Clínico Vinculado, Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain., Ayuso C; Department of Genetics & Genomics, Instituto de Investigación Sanitaria-Fundación Jiménez Díaz University Hospital - Universidad Autónoma de Madrid (IIS-FJD, UAM), 28040 Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain., González-Neira A; Spanish National Cancer Research Centre, Human Genotyping-CEGEN Unit, 28029 Madrid, Spain., Riancho JA; IDIVAL, 39008 Cantabria, Spain.; Universidad de Cantabria, 39008 Cantabria, Spain.; Hospital U M Valdecilla, 39008 Cantabria, Spain., Rojas-Martinez A; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, 64718 Monterrey, Mexico., Flores C; Genomics Division, Instituto Tecnológico y de Energías Renovables, 38600 Santa Cruz de Tenerife, Spain.; Research Unit, Hospital Universitario N.S. de Candelaria, 38010 Santa Cruz de Tenerife, Spain.; Centre for Biomedical Network Research on Respiratory Diseases (CIBERES), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Facultad de Ciencias de la Salud, Universidad Fernando Pessoa Canarias, 35450 Las Palmas de Gran Canaria, Spain., Lapunzina P; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Instituto de Genética Médica y Molecular (INGEMM), Hospital Universitario La Paz-IDIPAZ, 28046 Madrid, Spain.; ERN-ITHACA-European Reference Network., Carracedo A; Centro Nacional de Genotipado (CEGEN), Universidade de Santiago de Compostela, 15706 Santiago de Compostela, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Instituto de Investigación Sanitaria de Santiago (IDIS), 15706 Santiago de Compostela, Spain.; Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CIMUS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.; Fundación Pública Galega de Medicina Xenómica, Sistema Galego de Saúde (SERGAS), 15706 Santiago de Compostela, Spain.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2022 Nov 10; Vol. 31 (22), pp. 3789-3806.