Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mizuyo Kurazono"'
Autor:
Takahisa Maruyama, Eiji Matsuhisa, Hiromi Meiji Seika Kaisha Ltd. Takata, Eiki Shitara, Katsuyoshi Iwamatsu, Yuko Kano, Toshihiko Takata, Yasuo Yamamoto, Mizuyo Kurazono, Kunio Atsumi
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:6379-6387
A new series of 1β-methyl carbapenems possessing a 6,7-disubstituted imidazo[5,1- b ]thiazol-2-yl group directly attached to the C-2 position of the carbapenem nucleus was prepared, and the activities of these compounds against methicillin-resistant
Synthesis and SAR study of novel 7-(pyridinium-3-yl)-carbonyl imidazo[5,1-b]thiazol-2-yl carbapenems
Autor:
Katsuyoshi Iwamatsu, Yasuo Yamamoto, Takahisa Maruyama, Kunio Atsumi, Eiki Shitara, Mizuyo Kurazono, Yuko Kano
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:392-402
A new series of 1β-methyl carbapenems, possessing a 7-substituted imidazo[5,1- b ]thiazol-2-yl group directly attached to the C-2 position of the carbapenem nucleus, was synthesized and evaluated for antibacterial activity. These compounds showed po
Autor:
Minoru Yonezawa, Takayoshi Fukushima, Takahisa Suzuki, Kumiko Maeda, Mizuyo Kurazono, Yumiko Sanbongi, Matsuhisa Inoue, Kimiko Ubukata, Takashi Ida
Publikováno v:
Journal of Infection and Chemotherapy. 11:107-111
We investigated the antibacterial activities of 19 beta-lactams against three recombinant bacterial strains, in which three penicillin-binding protein genes, pbp2x, pbp1a, and pbp2b, from penicillin-resistant Streptococcus pneumoniae (PRSP), were tra
Autor:
Eiki Shitara, Minoru Yonezawa, Yoko Hirai, Takahisa Maruyama, Mizuyo Kurazono, Takashi Ida, Keiko Yamada
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:2831-2837
ME1036, formerly CP5609, is a novel parenteral carbapenem with a 7-acylated imidazo[5,1- b ]thiazole-2-yl group directly attached to the carbapenem moiety of the C-2 position. The present study evaluated the in vitro activities of ME1036 against clin
Autor:
Mizuyo Kurazono, Toshie Sugano, Yoko Hirai, Sho Takahata, Jun Nagura, Minoru Yonezawa, Eiki Shitara, Keiko Yamada, Yukari Tanaka, Koji Kijima, Yoshihiro Takayama
Publikováno v:
Antimicrobial Agents and Chemotherapy. 49:3526-3528
The efficacy of ME1036, a novel parenteral carbapenem, was compared with that of vancomycin by using a rabbit model of methicillin-resistant Staphylococcus aureus (MRSA) endocarditis. Compared with vancomycin, ME1036 reduced the bacterial counts in t
Autor:
Kunio Atsumi, Yuko Kano, Eiki Shitara, Katsuyoshi Iwamatsu, Mizuyo Kurazono, Takahisa Maruyama, Yasuo Yamamoto
Publikováno v:
ChemInform. 40
A new series of 1β-methyl carbapenems possessing a 6,7-disubstituted imidazo[5,1-b]thiazol-2-yl group directly attached to the C-2 position of the carbapenem nucleus was prepared, and their activities against methicillin-resistant Staphylococcus aur
Autor:
Takahisa Maruyama, Eiki Shitara, Kunio Atsumi, Yasuo Yamamoto, Mizuyo Kurazono, Yuko Kano, Katsuyoshi Iwamatsu
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(2)
A new series of 1β-methyl carbapenems possessing a 6,7-disubstituted imidazo[5,1-b]thiazol-2-yl group directly attached to the C-2 position of the carbapenem nucleus was prepared, and their activities against methicillin-resistant Staphylococcus aur
Autor:
Mizuyo Kurazono, Yasuo Yamamoto
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(6)
A new class of indole-containing compounds were prepared by the use of three component reaction and their in vitro antibacterial activities (MIC) were evaluated against Staphylococcus aureus and Enterococcus faecium including MRSA and VRE.
Autor:
Mizuyo Kurazono, Kazuhiko Irinoda, Takashi Ida, Masato Nonoyama, Ryoichi Okamoto, Matsuhisa Inoue
Publikováno v:
Antimicrobial agents and chemotherapy. 46(5)
We encountered three clinical isolates of methicillin-resistant Staphylococcus aureus which were susceptible to netilmicin and arbekacin in the absence of β-lactam antibiotics but which were resistant to them in the presence of β-lactam antibiotics
Autor:
Kumiko Maeda, Takashi Ida, Yumiko Sanbongi, Takahisa Suzuki, Takayoshi Fukushima, Mizuyo Kurazono, Minoru Yonezawa, Kimiko Ubukata, Matsuhisa Inoue
Publikováno v:
Journal of Infection & Chemotherapy (Springer Science & Business Media B.V.); Apr2005, Vol. 11 Issue 2, p107-111, 5p