Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mizuki Sone"'
Autor:
Takeshi Toyoda1 t-toyoda@nihs.go.jp, Mizuki Sone1,2, Kohei Matsushita1, Hirotoshi Akane1, Jun-ichi Akagi1, Tomomi Morikawa1, Yasuko Mizuta1, Young-Man Cho1, Kumiko Ogawa1
Publikováno v:
Journal of Toxicological Sciences. Jun2023, Vol. 48 Issue 6, p323-332. 10p.
Autor:
Takeshi Toyoda, Akiyoshi Nishikawa, Kumiko Ogawa, Mizuki Sone, Tomomi Morikawa, Jun-ichi Akagi, Yasuko Mizuta, Kohei Matsushita, Young-Man Cho
Publikováno v:
Journal of Applied Toxicology. 39:868-876
Phosphorylated histone H2AX (γ-H2AX) has been demonstrated as a DNA damage marker both in vitro and in vivo. We previously reported the effects of genotoxic carcinogens in the urinary bladder of rats by immunohistochemical analysis of γ-H2AX using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be50ae658b5e5920d1238c735ad634c7
https://doi.org/10.1002/jat.3775
https://doi.org/10.1002/jat.3775
Publikováno v:
Journal of Toxicologic Pathology
In this study, we aimed to evaluate changes in the acute toxicity of intraperitoneally administered silver nanoparticles (AgNPs) of varying sizes in BALB/c mice. Seven-week-old female BALB/c mice were intraperitoneally administered AgNPs measuring 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab9d1f39f462837052b76acd4723325
http://europepmc.org/articles/PMC5820107
http://europepmc.org/articles/PMC5820107
Publikováno v:
Journal of Toxicologic Pathology
Spontaneous massive infarction of mammary gland tumors has been reported to occur infrequently in humans. A subcutaneous mass (18 × 17 × 10 mm) was observed in the right axilla extending to the chest region of a 110-week-old female Wistar Hannover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f996d0c7f55273727f4fe80887e277f
http://europepmc.org/articles/PMC5293692
http://europepmc.org/articles/PMC5293692
Autor:
Kazunori Oyama, Makoto Miyagawa, Jiro Yokoyama, Mizuki Sone, Katsuhiko Nishimori, Takahiro Shimoda, Tomokazu Fukuda
Publikováno v:
Animal science journal = Nihon chikusan Gakkaiho. 89(8)
Human epigenetic studies suggest that consumption of seaweed prevents mammary cancer, which possibly is explained by iodine daily intake. In this study, we evaluated the efficacy of dietary intake of iodine-enriched eggs on mammary tumor incidence ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10afe5b055813e69a7d08856a825c314
https://pubmed.ncbi.nlm.nih.gov/29770537
https://pubmed.ncbi.nlm.nih.gov/29770537
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 78:1813-1816
Previously, using the Keratin5-Cre transgenic mouse model we reported that female Lgr4-conditional KO mice (Lgr4K5 KO) showed subfertility with defective stromal decidualization due to abnormal development of the uterine gland. However, the impact of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cfddff6e94845bc71ffe6f845c1dcea
https://doi.org/10.1080/09168451.2014.936353
https://doi.org/10.1080/09168451.2014.936353
Autor:
Mizuki Sone, Katsuhiko Nishimori, Kazunori Oyama, Ryotaro Hayashi, Yasuaki Mohri, Hans Clevers
Publikováno v:
FASEB Journal, 27(12), 4917-4928. FASEB
In previous work we generated mice with a tissue specific ablation of a leucine-rich repeat containing G-protein-coupled receptor 4 (Lgr4) using the Keratin-5 (K5) Cre transgenic mouse strain (Lgr4(K5 KO)). Interestingly, the Lgr4(K5 KO) female mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320142f599ceb39723f0780d34f2a99b
https://doi.org/10.1096/fj.13-232215
https://doi.org/10.1096/fj.13-232215
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 76:888-891
In mice, homozygous Lgr4 inactivation results in hypoplastic kidneys. To understand better the role of LGR4 in kidney development, we performed an analysis of kidneys in Lgr4-/- embryos. We stained Lgr4-/- kidneys with anti-WT1 and anti-Cleaved Caspa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5937cc1ce1eb56fbdcf67eadea9980
https://doi.org/10.1271/bbb.110834
https://doi.org/10.1271/bbb.110834
Publikováno v:
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation. 5(4)
We have analyzed the function of LGR4 in the development of various mouse epithelial tissues. Here we first report the retarded invasion of mammary ducts into the fat pad observed in Lgr4K5 KO mice at 4 weeks, compared with that of age-matched Lgr4K5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745bc193e30b9a0ba590d235483b6f65
https://pubmed.ncbi.nlm.nih.gov/21791950
https://pubmed.ncbi.nlm.nih.gov/21791950
Autor:
Young-Man Cho1 ymcho@nihs.go.jp, Yasuko Mizuta1, Jun-ichi Akagi1, Takeshi Toyoda1, Mizuki Sone1, Kumiko Ogawa1
Publikováno v:
Journal of Toxicologic Pathology. 2018, Vol. 31 Issue 1, p73-80. 8p.