Kdm4d mutant mice show impaired sperm motility and subfertility

Autor: Zhuoran XU, Yuka FUJIMOTO, Mizuki SAKAMOTO, Daiyu ITO, Masahito IKAWA, Takashi ISHIUCHI

Publikováno v: The Journal of Reproduction and Development, Vol 70, Iss 5, Pp 320-326 (2024)

Regulation of gene expression through histone modifications underlies cell homeostasis and differentiation. Kdm4d and Kdm4dl exhibit a high degree of similarity and demethylate H3K9me3. However, the physiological functions of these proteins remain un

Externí odkaz: https://doaj.org/article/06f7941772a94cc8b6f84b4c180e427e

Detection of newly synthesized RNA reveals transcriptional reprogramming during ZGA and a role of Obox3 in totipotency acquisition

Autor: Mizuki Sakamoto, Aoi Ito, Sayaka Wakayama, Hiroyuki Sasaki, Teruhiko Wakayama, Takashi Ishiuchi

Publikováno v: Cell Reports, Vol 43, Iss 4, Pp 114118- (2024)

Summary: Zygotic genome activation (ZGA) after fertilization enables the maternal-to-zygotic transition. However, the global view of ZGA, particularly at initiation, is incompletely understood. Here, we develop a method to capture and sequence newly

Externí odkaz: https://doaj.org/article/9ed8ec9cff2f42ee8f95fda64a19b2b8

Toll-like receptor 9-positive plasmacytoid dendritic cells promote Th17 immune responses in oral lichen planus stimulated by epithelium-derived cathepsin K

Autor: Yuka Miyahara, Hu Chen, Masafumi Moriyama, Keita Mochizuki, Naoki Kaneko, A. S. M. Rafiul Haque, Akira Chinju, Kazuki Kai, Mizuki Sakamoto, Noriko Kakizoe-Ishiguro, Masaki Yamauchi, Kenichi Ogata, Tamotsu Kiyoshima, Shintaro Kawano, Seiji Nakamura

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)

Abstract Oral lichen planus (OLP) is a chronic inflammatory disease associated with T cell infiltration. The crosstalk between oral epithelium and mucosal T cells was considered to be crucial in the pathogenesis of OLP. Here, we selectively extracted

Externí odkaz: https://doaj.org/article/935a8d70adfb45f1bd3704f276984210

Overview of recent experimental results on the EAST Tokamak

Autor: X. Gong, on behalf of EAST Team and Collaborators, The EAST Team:, Yuntao Song, Baonian Wan, Jiangang Li, Yuanxi Wan, Xinchao Wu, Fukun Liu, Junling Chen, Jiansheng Hu, Guosheng Xu, Kun Lu, Xianzu Gong, Bingjia Xiao, Yu Wu, Xiang Gao, Damao Yao, Nong Xiang, Liqun Hu, Chundong Hu, Jiefeng Wu, Biao Shen, Ge Gao, Yiyun Huang, Liuwei Xu, Qiyong Zhang, Cheonho Bae, Bin Cao, Lei Cao, Jiafeng Chang, Dalong Chen, Ran Chen, Xiaojiao Chen, Yebin Chen, Yue Chen, Yunxin Cheng, Yong Cheng, Bojiang Ding, Fang Ding, Rui Ding, Shijun Du, Yanmin Duan, Jia Fu, Daming Gao, Wei Gao, Yongqi Gu, Bin Guo, Fei Guo, Yong Guo, Xiaofeng Han, Shiying He, Ailan Hu, Chang Hu, Guanghai Hu, Huaichuan Hu, Qingsheng Hu, Yanlan Hu, Zhenhua Hu, Juan Huang, Liansheng Huang, Ming Huang, Ronglin Huang, Xiang Ji, Hua Jia, Caichao Jiang, Yinxian Jie, Songqing Ju, Defeng Kong, Erzhong Li, Guoqiang Li, Jiahong Li, Junjun Li, Miaohui Li, Pan Li, Kedong Li, Shi Li, Yadong Li, Lizhen Liang, Yanchuan Liao, Shiyao Lin, Xin Lin, Bili Ling, Haiqing Liu, Huajun Liu, Jianwen Liu, Liang Liu, Shaocheng Liu, Sheng Liu, Wenbin Liu, Xiaoju Liu, Xiaoyan Liu, Yong Liu, Zhihong Liu, Zhimin Liu, Jianhua Lu, Zhengping Luo, Dengkui Ma, Huafeng Mao, Wendong Ma, Songtao Mao, Yuzhou Mao, Tingfeng Ming, Chao Pan, Chengkang Pan, Shengmin Pan, Jing Qian, Jinping Qian, Chengming Qin, Zhiyong Qiu, Qilong Ren, Zhicai Sheng, Shihua Song, Pengjun Sun, Xiaoyang Sun, Youwen Sun, Tian Tang, Ling Tao, Ang Ti, Baoguo Wang, Feng Wang, Fudi Wang, Huihui Wang, Jian Wang, Liang Wang, Linsen Wang, Mao Wang, Ping Wang, Xiaojie Wang, Shouxin Wang, Yating Wang, Yuehang Wang, Yong Wang, Zhengchu Wang, Jianglong Wei, Jing Wei, Xuechao Wei, Bin Wu, Dajun Wu, Hao Wu, Jinhua Wu, Xiangming Wu, Yibing Wu, Zege Wu, Weibin Xi, Tianyang Xia, Yezheng Xiao, Yahong Xie, Yuanlai Xie, Handong Xu, Liqing Xu, Weiye Xu, Ning Yan, Rong Yan, Jianhua Yang, Lei Yang, Qingxi Yang, Yao Yang, Zhongshi Yang, Min Yu, Yaowei Yu, Qiping Yuan, Shuai Yuan, Qing Zang, Bin Zhang, Jian Zhang, Jizong Zhang, Liyuan Zhang, Ling Zhang, Ruirui Zhang, Shoubiao Zhang, Tao Zhang, Wei Zhang, Xinjun Zhang, Xiuqing Zhang, Yang Zhang, Zuchao Zhang, Hailin Zhao, Lianmin Zhao, Guoqiang Zhong, Ruijie Zhou, Haishan Zhou, Tianhu Zhou, Yue Zhou, Dahuan Zhu, Haisheng Zhu, Ping Zhu, Zeying Zhu, Huidong Zhuang, Zibo Zhou, Zhiyong Zhou, Zhiwei Zhou, Guizhong Zuo, International and Domestic Collaborators:, Huishan Cai, Weixing Ding, Tao Lan, Adi Liu, Wandong Liu, Shaojie Wang, Minyou Ye, Yi Yu, Ge Zhuang, Wei Chen, Guangjiu Lei, Lin Nie, Min Xu, Huang Yuan, Nanhua Yao, Zhe Gao, Long Zeng, Tieshuan Fan, Liu Chen, Guoyong Fu, Zhiwei Ma, Zengmao Sheng, Yong Xiao, Xiaogang Wang, Zhongyong Chen, Yonghua Ding, Xiwei Hu, Zijiang Wang, Fangchuan Zhong, Hongbin Ding, Dezhen Wang, Zhengxiong Wang, Chenggang Jin, Xuemei Wu, Xiaofei Yang, Jianhua Zhang, Qingyuan Hu, Xi Yuan, Changqi Chen, Shuyi Gan, Xudi Wang, Congzhong Wu, Chongwei Zhang, Ting Zhang, Wu Zhu, Erhua Kong, Kaisong Wang, Chuanli Wang, Hongtao Yang, Lixiang Zhang, Yuhong Xu, Paul Anderson, Gheni Abla, Vincent Chan, John L. Doane, Andrea Garofalo, Punit Gohil, Chung Lih Hsieh, Ruey Hong, David Humphreys, Alan Walter Hyatt, Gary Jackson, Lang Lao, Yueqiang Liu, James Leuer, John Lohr, Mohamad Ali Mahdavi, Robert Olstad, Ben Penaflor, Ron Prater, David Piglowski, Michael Schaffe, Tim Scoville, Wayne Solomon, Mike Walker, Anders Welander, Manfred Bitter, Robert Budny, Robert A. Ellis, Nat Fisch, Rich Hawryluk, Kenneth W. Hill, Joel Hosea, Michael A. Jaworski, Egemen Kolemen, Rajesh Maingi, Dennis Mansfield, Dana M. Mastrovito, Jonathan Menard, Dennis Mueller, Novmir Pablant, Lane Roquemore, Filippo Scotti, Gary Taylor, Kevin Tritz, Randy Wilson, Michael Zarnstorff, Seung Gyou Baek, Beck Bill, Paul T. Bonoli, Robert Granetz, Ron Parker, Shunichi Shiraiwa, Josh Stillerman, Greg Wallace, Stephen Wukitch, Lihua Zhou, He Huang, Kenneth Gentle, Ken Liao, Perry Philippe, William L. Rowan, Linjin Zheng, Patrick H. Diamond, George R. Tynan, Nicolas Fedorczak, Peter Manz, Lei Zhao, David Brower, William W. Heidbrink, Yubao Zhu, Calvin W. Domier, Neville C. Luhmann, Chris Holcomb, Xueqiao Xu, Eric Wang, Max E. Fenstermarcher, Mickey Wade, Donald L. Hillis, Steve Meitner, Igor V. Vinyar, Vladimir Davydenko, Igor Shikhovtsev, Naoko Ashikawa, Kasahara Hiroshi, Katsumi Ida, Shinichiro Kado, Tomita Kawamura, Saito Kenji, Ryuhei Kumazawa, Ogawa Kunihiro, Isobe Mitsutaka, Shigeru Morita, Haruhisa Nakano, Masaki Osakabe, Mizuki Sakamoto, Yasuhiko Takeiri, Kazuo Toi, Katsuyoshi Tsumori, Nobuta Yuji, Masaya Hanada, Mitsuru Kikuchi, Atsushi Kojima, Kazuhiro Watanabe, Jean-Francois Artaud, Vincent Basiuk, F. Bouquey, B. Bremond, Laurent Colas, Joan Decker, D. Douai, Annika Ekedahl, Christel Fenzi, Eric Gauthier, Gerardo Giruzzi, Marc Goniche, Dominique Guilhem, Walid Helou, Julien Hillairet, Tuong Hoang, Philippe Huynh, Frederic Imbeaux, Xavier Litaudon, Roland Magne, Yves Peysson, K. Vueillie, Xiaolan Zou, Alberto Loarte, Richard Pitts, Tom Wauters, Franz Braun, R. Bilato, Volodymyr Bobkov, J.M. Noterdaeme, Qingquan Yu, Yunfeng Liang, Jonny Pearson, Michael Rack, Joseph Banks, John Fessey, Charles Monroe, Damian King, Stefan Schmuck, Hongjuan Sun, Paul Trimble, Tom Todd, Jun-Gyo Bak, Suk-Ho Hong, Sangong Lee, Bae Young Soon, Oh Byung Hoon, Chang Doo Hee, Lee Kwang Won, Luca Amicucci, Giuseppe Calabro, Silvio Ceccuzzi, Roberto Cesario, Flavio Crisanti, Edmondo Giovannozzi, Giuseppe Ramogida, Gianmaria De Tommasi, Angelo Antonio Tuccillo, Bruno Viola, Raffaele Albanese, Roberto Ambrosino, Lucio Barbato, Stefano Mastrostefano, Alfredo Pironti, Vincenzo Pericoli Ridolfini, Rory Scannell, Fabio Villone, Volker Naulin, Anders H. Nielsen, Roman Zagorsky, Sandor Zoletnik, Chijin Xiao, B. Madsen, M. Salewski, Eugenio Schuster

Publikováno v: Nuclear Fusion, Vol 64, Iss 11, p 112013 (2024)

Since the last IAEA-FEC in 2021, significant progress on the development of long pulse steady state scenario and its related key physics and technologies have been achieved, including the reproducible 403 s long-pulse steady-state H-mode plasma with

Externí odkaz: https://doaj.org/article/e7d8d2e749f749ba980b1e4d3ca6cf2b

Fuel recycling control in long pulse operation with full tungsten divertors in EAST tokamak

Autor: Yaowei Yu, Deze Zhou, Mizuki Sakamoto, Bin Cao, Guizhong Zuo, Jiansheng Hu

Publikováno v: Nuclear Materials and Energy, Vol 34, Iss , Pp 101333- (2023)

Fuel recycling control in long pulse discharges is studied in EAST tokamak with tungsten divertors by particle balance. Double null configuration, proper Resonant Magnetic Perturbation (RMP), divertor cryopumps and realtime lithium injection, are all

Externí odkaz: https://doaj.org/article/481ffdfa69854ff6a1be452617f0c80c