Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mizuki Ochi"'
Autor:
Makoto Kuwahara, Wataru Ise, Mizuki Ochi, Junpei Suzuki, Kohei Kometani, Saho Maruyama, Maya Izumoto, Akira Matsumoto, Nobuaki Takemori, Ayako Takemori, Kenta Shinoda, Toshinori Nakayama, Osamu Ohara, Masaki Yasukawa, Tatsuya Sawasaki, Tomohiro Kurosaki, Masakatsu Yamashita
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Bach2 limits T cell effector functions. Here the authors show that Bach2–Batf complex antagonizes the recruitment of the Batf–Irf4 complex to AP-1 motifs and suppresses Th2 cytokine production, and describe mechanisms of negative feedback by whic
Externí odkaz:
https://doaj.org/article/46c2c5dacb5943f286af54fec57af3ac
Autor:
Junpei Suzuki, Masakatsu Yamashita, Mika Horiuchi, Makoto Kuwahara, Masumi Mizuki, Mizuki Ochi, Saho Maruyama, Tatsuya Sawasaki, Masaki Yasukawa, Hidekazu Tamauchi, Jinfang Zhu
Publikováno v:
Immunology. 147:476-487
A transcriptional repressor Gfi1 promotes T helper type 2 (Th2) cell development and inhibits Th17 and inducible regulatory T‐cell differentiation. However, the role of Gfi1 in regulating Th1 cell differentiation and the Th1‐type immune response
Autor:
Toshinori Nakayama, Osamu Ohara, Tatsuya Sawasaki, Junpei Suzuki, Akira Matsumoto, Ayako Takemori, Nobuaki Takemori, Kohei Kometani, Maya Izumoto, Makoto Kuwahara, Masaki Yasukawa, Saho Maruyama, Masakatsu Yamashita, Kenta Shinoda, Tomohiro Kurosaki, Wataru Ise, Mizuki Ochi
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Although Bach2 has an important role in regulating the Th2-type immune response, the underlying molecular mechanisms remain unclear. We herein demonstrate that Bach2 associates with Batf and binds to the regulatory regions of the Th2 cytokine gene lo