Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mizuho Tanabe"'
Autor:
Tomonori Igarashi, Ichiro Niina, Yasutomo Momii, Takayuki Torigoe, Mizuho Tanabe, Michihiko Kuwano, Kimitoshi Kohno, Takuya Imaizumi, Tetsuro Wakasugi, Hiroto Izumi, Takeshi Yoshida, Yoichiro Yoshida, Hiroshi Ishiguchi
Publikováno v:
Current Medicinal Chemistry-Anti-Cancer Agents. 5:15-27
Cisplatin is one of the most potent and widely used anti-cancer agents in the treatment of various solid tumors. However, the development of resistance to cisplatin is a major obstacle in clinical treatment. Several mechanisms are thought to be invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cfd3ad286d55b96fa8bf92465743065
https://doi.org/10.2174/1568011053352587
https://doi.org/10.2174/1568011053352587
Autor:
Mizuho Tanabe, Hidetaka Uramoto, Hiroshi Ishiguchi, Tomoko Ise, Takayuki Torigoe, Hiroto Izumi, Tadashi Murakami, Takeshi Yoshida, Yoichiro Yoshida, Kimitoshi Kohno, Minoru Nomoto
Publikováno v:
Cancer Treatment Reviews. 29:541-549
One of the major obstacles to the successful treatment of cancer is the complex biology of solid tumour development. Although regulation of intracellular pH has been shown to be critically important for many cellular functions, pH regulation has not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8921372b043048a54c0d67658e2793bf
https://doi.org/10.1016/s0305-7372(03)00106-3
https://doi.org/10.1016/s0305-7372(03)00106-3
Autor:
Hidetaka Uramoto, Takayuki Torigoe, Takeshi Yoshida, Yoichiro Yoshida, Hiroshi Ishiguchi, Mizuho Tanabe, Tadashi Murakami, Tomoko Ise, Hiroto Izumi, Kimitoshi Kohno
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1628:97-104
The vacuolar-ATPase (V-ATPase) is a multi-subunit enzyme that couples ATP hydrolysis to proton pumping across membranes. V-ATPase genes are considered to be housekeeping genes and are expressed in human neoplastic tissue and in cell lines. We have is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69abe5ff1d68d273a8ffbaa56390f68
https://doi.org/10.1016/s0167-4781(03)00119-2
https://doi.org/10.1016/s0167-4781(03)00119-2
Autor:
Takayuki Torigoe, Mizuho Tanabe, Tadashi Murakami, Minoru Nomoto, Kimitoshi Kohno, Yoichiro Yoshida, Hiroshi Ishiguchi, Hidetaka Uramoto, Tomoko Ise, Hiroto Izumi
Publikováno v:
Anti-Cancer Drugs. 13:237-243
Tumor cells in vivo often exist in a hypoxic microenvironment with a lower extracellular pH than that surrounding normal cells. Ability to upregulate proton extrusion may be important for tumor cell survival. Such microenvironmental factors may be in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::767810d568302a8a54ceec42b25cc232
https://doi.org/10.1097/00001813-200203000-00005
https://doi.org/10.1097/00001813-200203000-00005
Publikováno v:
Pharmacogenetics. 11:175-184
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe7f4f8d700eb4d9fbba4dd42d2008f
https://doi.org/10.1097/00008571-200103000-00008
https://doi.org/10.1097/00008571-200103000-00008
Autor:
Mizuho Tanabe, Yasuyuki Sasaguri, Kenji Sugio, Kimitoshi Kohno, Tomonori Igarashi, Ke-Yong Wang, Kosei Yasumoto, Tokuzo Arao, Hidetaka Uramoto, Kazuto Nishio, Hiroto Izumi, Yutaka Otsuji, Takeshi Uchiumi
Publikováno v:
Oncogene. 26(33)
The mechanisms underlying cellular drug resistance have been extensively studied, but little is known about its regulation. We have previously reported that activating transcription factor 4 (ATF4) is upregulated in cisplatin-resistant cells and play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87dc51e6ff084a34f1f705808f4b4469
https://pubmed.ncbi.nlm.nih.gov/17297441
https://pubmed.ncbi.nlm.nih.gov/17297441
Publikováno v:
Biochemical and biophysical research communications. 329(1)
To explore the mechanism of glucocorticoid-induced osteoporosis, we investigated the effect of glucocorticoid on canonical Wnt signaling that emerged as a novel key pathway for promoting bone formation. Wnt3a increased the T-cell factor (Tcf)/lymphoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a83b925ed79c0663c86c129666a281
https://pubmed.ncbi.nlm.nih.gov/15721290
https://pubmed.ncbi.nlm.nih.gov/15721290
Autor:
Mizuho, Tanabe, Hiroto, Izumi, Tomoko, Ise, Shun, Higuchi, Takao, Yamori, Kosei, Yasumoto, Kimitoshi, Kohno
Publikováno v:
Cancer research. 63(24)
Resistance to cisplatin is a major problem in the treatment of solid tumors. To investigate the determinants of cisplatin resistance, we have identified cisplatin-inducible genes by differential display of mRNA. One of the cisplatin-inducible genes w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04c097221b652ae9320bf7898b46fc30
https://pubmed.ncbi.nlm.nih.gov/14695168
https://pubmed.ncbi.nlm.nih.gov/14695168
Autor:
Hideaki Itoh, Kimitoshi Kohno, Mizuho Tanabe, Hidetaka Uramoto, Tomoko Ise, Hiroshi Ishiguchi, Yoichiro Yoshida, Hiroto Izumi, Takayuki Torigoe, Tadashi Murakami, Minoru Nomoto
Publikováno v:
The Journal of biological chemistry. 277(39)
We have isolated two overlapping genomic clones that contain the 5'-terminal portion of the human vacuolar H(+)-ATPase c subunit (ATP6L) gene. The sequence preceding the transcription initiation site, which is GC-rich, contains four GC boxes and one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b6dafd82b4bdc6d609762bf42e5256
https://pubmed.ncbi.nlm.nih.gov/12133827
https://pubmed.ncbi.nlm.nih.gov/12133827
Autor:
Takayuki Torigoe, Yoshifumi Nakayama, Kimitoshi Kohno, Tadashi Murakami, Yoichiro Yoshida, Hideaki Itoh, Hiroshi Kasai, Tomoko Ise, Hidetaka Uramoto, Hiroto Izumi, Mizuho Tanabe, Hiroshi Ishiguchi
Publikováno v:
Biochemical and biophysical research communications. 295(4)
Mitochondrial transcription factor A (mtTFA) is necessary for both transcription and maintenance of mtDNA, and is also one of the high mobility group (HMG) proteins that preferentially binds to cisplatin-damaged DNA. In this study we confirmed the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e6843b98cf3322a8b509f4818b6a95
https://pubmed.ncbi.nlm.nih.gov/12127986
https://pubmed.ncbi.nlm.nih.gov/12127986