Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Mizuho Kittaka"'
Autor:
Tetsuya Yoshimoto, Mizuho Kittaka, Andrew Anh Phuong Doan, Rina Urata, Matthew Prideaux, Roxana E. Rojas, Clifford V. Harding, W. Henry Boom, Lynda F. Bonewald, Edward M. Greenfield, Yasuyoshi Ueki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
MYD88 mediates the signal of bacterial infection. Here, in the context of periodontal infection, the authors show that the MYD88 pathway in osteocytes plays a dominant role in regulating osteolysis.
Externí odkaz:
https://doaj.org/article/e16f005c0ee94c278ec83641515e371c
Publikováno v:
Frontiers in Bioinformatics, Vol 2 (2022)
Osteoclasts are multinucleated cells that exclusively resorb bone matrix proteins and minerals on the bone surface. They differentiate from monocyte/macrophage lineage cells in the presence of osteoclastogenic cytokines such as the receptor activator
Externí odkaz:
https://doaj.org/article/c76e88be9b594650b3f8d83463694eaf
Autor:
Mizuho Kittaka, Tetsuya Yoshimoto, Collin Schlosser, Mikihito Kajiya, Hidemi Kurihara, Ernst J Reichenberger, Yasuyoshi Ueki
Publikováno v:
JBMR Plus, Vol 4, Iss 6, Pp n/a-n/a (2020)
ABSTRACT Cherubism (OMIM#118400) is a craniofacial disorder characterized by destructive jaw expansion. Gain‐of‐function mutations in SH3‐domain binding protein 2 (SH3BP2) are responsible for this rare disorder. We have previously shown that ho
Externí odkaz:
https://doaj.org/article/771a4998294a42b7801c0c626ba58eb0
Publikováno v:
Bone Reports, Vol 12, Iss , Pp 100258- (2020)
Even though the receptor activator of the nuclear factor-κB ligand (RANKL) and its receptor RANK have an exclusive role in osteoclastogenesis, the possibility of RANK/RANKL-independent osteoclastogenesis has been the subject of a long-standing debat
Externí odkaz:
https://doaj.org/article/8a18c3724bfa47d594a4248bef8b32be
Autor:
Teruhito Yoshitaka, Tomoyuki Mukai, Mizuho Kittaka, Lisa M. Alford, Salome Masrani, Shu Ishida, Ken Yamaguchi, Motohiko Yamada, Noriyoshi Mizuno, Bjorn R. Olsen, Ernst J. Reichenberger, Yasuyoshi Ueki
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 1752-1766 (2014)
Cherubism is caused by mutations in SH3BP2. Studies of cherubism mice showed that tumor necrosis factor α (TNF-α)-dependent autoinflammation is a major cause of the disorder but failed to explain why human cherubism lesions are restricted to jaws a
Externí odkaz:
https://doaj.org/article/5453dcbdd4d64aed8b946a1fbb2113bc
Autor:
Tomoyuki Mukai, Richard Gallant, Shu Ishida, Teruhito Yoshitaka, Mizuho Kittaka, Keiichiro Nishida, David A Fox, Yoshitaka Morita, Yasuyoshi Ueki
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105518 (2014)
SH3BP2 is a signaling adapter protein which regulates immune and skeletal systems. Gain-of-function mutations in SH3BP2 cause cherubism, characterized by jawbone destruction. This study was aimed to examine the role of SH3BP2 in inflammatory bone los
Externí odkaz:
https://doaj.org/article/55344c38147d466ba48414f194b2723d
Autor:
Xue Yuan, Vedanshi Amin, Tianli Zhu, Mizuho Kittaka, Yasuyoshi Ueki, Teresita M. Bellido, Hakan Turkkahraman
Publikováno v:
Journal of Periodontology. 94:277-289
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::163c8d6cddaae674c967f6ce49ca8ffc
https://doi.org/10.1002/jper.22-0192
https://doi.org/10.1002/jper.22-0192
Autor:
Sumie Hiramatsu Asano, Ikue Tosa, Toshitaka Oohashi, Masanori Iseki, Mizuho Kittaka, Katsuhiko Ishihara, Tomoyuki Mukai, Mitsuaki Ono, Yasuyoshi Ueki, Yoshitaka Morita, Ayano Yahagi, Takahiko Akagi
Publikováno v:
Oral Diseases. 29:1089-1101
Objective Cherubism is a genetic disorder characterised by bilateral jawbone deformation. The associated jawbone lesions regress after puberty, whereas severe cases require surgical treatment. Although several drugs have been tested, fundamental trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3f670f47f025c06cf49bde1e0fb6c2
https://doi.org/10.1111/odi.14073
https://doi.org/10.1111/odi.14073
Autor:
Xue, Yuan, Vedanshi, Amin, Tianli, Zhu, Mizuho, Kittaka, Yasuyoshi, Ueki, Teresita M, Bellido, Hakan, Turkkahraman
Publikováno v:
J Periodontol
Type I Diabetes Mellitus (T1DM) and periodontitis have long been thought to be biologically connected. Indeed, T1DM is a risk factor for periodontal disease. With the population of diabetic individuals growing, it's more important than ever to unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1136f3012810e4b768f64fe5d7e6b398
https://pubmed.ncbi.nlm.nih.gov/35869905
https://pubmed.ncbi.nlm.nih.gov/35869905
Autor:
Justin N Williams, Mavis Irwin, Yong Li, Anuradha Valiyakambrath, Brett T Mattingly, Sheel Patel, Mizuho Kittaka, Rebecca N Collins, Nicholas Clough, Emma H Doud, Amber L Mosley, Teresita M Bellido, Angela Bruzzaniti, Lilian I. Plotkin, Jonathan C. Trinidad, William R Thompson, Lynda F. Bonewald, Uma Sankar
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4718
Volume 24
Issue 5
Pages: 4718
Calcium/calmodulin (CaM)-dependent protein kinase kinase 2 (CaMKK2) regulates bone remodeling through its effects on osteoblasts and osteoclasts. However, its role in osteocytes, the most abundant bone cell type, and the master regulator of bone remo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb2e480e2ffef223a82db0e48bd2d0e
https://doi.org/10.3390/ijms24054718
https://doi.org/10.3390/ijms24054718