Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Mizuho Hasegawa"'
Autor:
Takashi Nishina, Yutaka Deguchi, Daisuke Ohshima, Wakami Takeda, Masato Ohtsuka, Shigeyuki Shichino, Satoshi Ueha, Soh Yamazaki, Mika Kawauchi, Eri Nakamura, Chiharu Nishiyama, Yuko Kojima, Satomi Adachi-Akahane, Mizuho Hasegawa, Mizuho Nakayama, Masanobu Oshima, Hideo Yagita, Kazutoshi Shibuya, Tetuo Mikami, Naohiro Inohara, Kouji Matsushima, Norihiro Tada, Hiroyasu Nakano
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The stromal fibroblast population in the colon is composed of heterogeneous and distinct cell subtypes that play a crucial role in the development of colitis and colon cancer. Here the authors generate IL-11 reporter mice and characterize the origin
Externí odkaz:
https://doaj.org/article/3db3ac661ebb40e88567f28d3824a2f8
Autor:
Masashi Ohno, Mizuho Hasegawa, Atsushi Hayashi, Gustavo Caballero-Flores, Christopher J Alteri, Trevor D Lawley, Nobuhiko Kamada, Gabriel Núñez, Naohiro Inohara
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008928 (2020)
Gut dysbiosis associated with intestinal inflammation is characterized by the blooming of particular bacteria such as adherent-invasive E. coli (AIEC). However, the precise mechanisms by which AIEC impact on colitis remain largely unknown. Here we sh
Externí odkaz:
https://doaj.org/article/935f58dcefaf4743a79d47e153d71f71
Autor:
Youssef Darzi, Yizu Jiao, Mizuho Hasegawa, Henry Moon, Gabriel Núñez, Naohiro Inohara, Jeroen Raes
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158866 (2016)
Strain NI1060 is an oral bacterium responsible for periodontitis in a murine ligature-induced disease model. To better understand its pathogenicity, we have determined the complete sequence of its 2,553,982 bp genome. Although closely related to Past
Externí odkaz:
https://doaj.org/article/043e576dbbb4452ebeafeb527c09a916
Autor:
Kouji Matsushima, Mizuho Hasegawa, Eri Nakamura, Kazutoshi Shibuya, Takashi Nishina, Daisuke Ohshima, Wakami Takeda, Norihiro Tada, Chiharu Nishiyama, Tetuo Mikami, Mizuho Nakayama, Shigeyuki Shichino, Hiroyasu Nakano, Mika Kawauchi, Masato Ohtsuka, Hideo Yagita, Naohiro Inohara, Satomi Adachi-Akahane, Masanobu Oshima, Soh Yamazaki, Yuko Kojima, Yutaka Deguchi, Satoshi Ueha
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Interleukin (IL)-11 is a member of the IL-6 family of cytokines and is involved in multiple cellular responses, including tumor development. However, the origin and functions of IL-11-producing (IL-11+) cells are not fully understood. To characterize
Publikováno v:
Am J Pathol
N-formyl peptide receptors (FPRs) serve as phagocyte pattern-recognition receptors that play a crucial role in the regulation of host defense against infection. Epithelial cells also express FPRs, and their activation during inflammation or injury re
Autor:
Hiroyasu Nakano, Yutaka Deguchi, Eri Nakamura, Masato Ohtsuka, Kazutoshi Shibuya, Takashi Nishina, Hideo Yagita, Daisuke Ohshima, Mizuho Nakayama, Mika Kawauchi, Wakami Takeda, Norihiro Tada, Mizuho Hasegawa, Chiharu Nishiyama, Naohiro Inohara, Satomi Adachi-Akahane, Masanobu Oshima, Soh Yamazaki, Yuko Kojima, Tetuo Mikami
SUMMARYInterleukin (IL)-11 is a member of the IL-6 family of cytokines and involved in multiple cellular responses, including tumor development. However, the origin and functions of IL-11-producing (IL-11+) cells are not fully understood. To characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e3cada8a9e1f5b821661058025f529
Autor:
Shuling Fan, Sven Flemming, Anny-Claude Luissint, Mizuho Hasegawa, Dennis H. M. Kusters, Arturo Raya-Sandino, Dennis W. Zhou, Vicky Garcia-Hernandez, Andrés J. García, Charles A. Parkos, Asma Nusrat
Publikováno v:
Molecular Biology of the Cell
The intestinal mucosa is lined by a single layer of epithelial cells that forms a tight barrier, separating luminal antigens and microbes from underlying tissue compartments. Mucosal damage results in a compromised epithelial barrier that can lead to
Autor:
Yukino Ukai, Yuki Kitamura, Miyu Okamoto, Mizuho Hasegawa, Hanaka Fukuishi, Naho Hara, Mayuko Sakanashi
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:1
Autor:
Christopher J. Alteri, Atsushi Hayashi, Gustavo Caballero-Flores, Trevor D. Lawley, Naohiro Inohara, Mizuho Hasegawa, Gabriel Núñez, Masashi Ohno, Nobuhiko Kamada
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 10, p e1008928 (2020)
PLoS Pathogens, Vol 16, Iss 10, p e1008928 (2020)
Gut dysbiosis associated with intestinal inflammation is characterized by the blooming of particular bacteria such as adherent-invasive E. coli (AIEC). However, the precise mechanisms by which AIEC impact on colitis remain largely unknown. Here we sh
Autor:
Nhu Do, Nobuhiko Kamada, Mengzhen Liu, Mizuho Hasegawa, Naohiro Inohara, Gabriel Núñez, Raúl Muñoz-Planillo, Shoko Yada
Publikováno v:
Immunity. 41(4):620-632
Summary Pathobionts play a critical role in disease development, but the immune mechanisms against pathobionts remain poorly understood. Here, we report a critical role for interleukin-22 (IL-22) in systemic protection against bacterial pathobionts t