Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mizuho Harashima"'
Autor:
Chieko Saito, Masashi Hyuga, Youko Nagaoka, Shingo Niimi, Minako Furukawa, Nana Kawasaki, Taiichiro Seki, Mizuho Harashima, Toyohiko Ariga
Publikováno v:
Journal of Biophysical Chemistry. :348-356
Dexamethasone (Dex), a ligand for transcriptional enhancement of tyrosine aminotransferase (TAT) and tryptophan 2,3-dioxygenase (TO) genes, (100 nM) maximally increased these mRNA levels at 12 h and 7 h in primary cultured rat hepatocytes and the nuc
Publikováno v:
Current Drug Therapy. 4:221-233
Autor:
Teruhide Yamaguchi, Yoshimasa Ito, Toyohiko Ariga, Masashi Hyuga, Mizuho Harashima, Kayo Harada, Taiichiro Seki, Shingo Niimi
Publikováno v:
Journal of Biochemistry. 143:537-545
Annexin (Anx) A3 increases and plays important roles in the signalling cascade in hepatocyte growth in cultured hepatocytes. However, no information is available on its expression and role in rat liver regeneration. In the present study, AnxA3 expres
Publikováno v:
Journal of Organ Dysfunction. 3:164-182
RNA interference (RNAi) is the process of sequence-specific gene silencing, initiated by small double-stranded RNA homologous in sequence to the target gene. Various factors involved in the regulation of hepatocyte function have been identified using
Autor:
Toru Kawanishi, Mizuho Harashima, Takao Hayakawa, Shingo Niimi, Toyohiko Ariga, Taiichiro Seki, Masashi Hyuga, Hitomi Koyanagi, Seiji Noma
Publikováno v:
Biological and Pharmaceutical Bulletin. 29:1339-1343
We have recently reported that annexin (Anx) A3 expression is necessary for hepatocyte growth in cultured rat hepatocytes seeded at half the subconfluent density on collagen. In the present study, we investigated the effects of various regulatory fac
Autor:
Takao Hayakawa, Kazuko Takayama, Toru Kawanishi, Shingo Niimi, Mizuho Harashima, Masashi Hyuga, Toyohiko Ariga, Taiichiro Seki, Mayumi Hara
Publikováno v:
The Journal of Biochemistry. 137:579-586
Thrombomodulin (TM) is a thrombin receptor on the surface of endothelial cells that converts thrombin from a procoagulant to an anticoagulant. Thrombin promotes invasion by various tumor cells, and positive or negative correlations are found between
Autor:
Taiichiro Seki, Mizuho Harashima, Toyohiko Ariga, Tadashi Oshizawa, Shingo Niimi, Toru Kawanishi, Teruhide Yamaguchi, Takao Hayakawa
Publikováno v:
Biochemical and Biophysical Research Communications. 300:770-774
Small hepatocytes are cells that express characteristic phenotypes such as a high growth potential and differentiation capacity. In order to identify rat-small-hepatocyte specific proteins, we separated the cellular proteins of isolated small and par
Publikováno v:
Biomedical research (Tokyo, Japan). 34(5)
In the present study, we investigated the role of p16(INK4a) in the inhibition of DNA synthesis stimulated by hepatocyte growth factor (HGF) or epidermal growth factor (EGF) using RNA interference in primary cultured rat hepatocytes. The transfection
Autor:
Taiichiro Seki, Takao Hayakawa, Shingo Niimi, Toyohiko Ariga, Toru Kawanishi, Masashi Hyuga, Mizuho Harashima, Masaru Gamou
Publikováno v:
Biologicalpharmaceutical bulletin. 28(3)
Annexin A3 is a member of the lipocortin/annexin family, which binds to phospholipids and membranes in a Ca(2+)-dependent manner. Although annexin A3 has various functions in vitro, its cellular significance is completely unknown. Annexin A3 is not f