Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Mizied Falah"'
Autor:
Ahmad Kadriya, Mizied Falah
Publikováno v:
Cells, Vol 12, Iss 15, p 1999 (2023)
Extracellular vesicle (EV) research has expanded substantially over the years. EVs have been identified in all living organisms and are produced and released as a means of intercellular communication or as a defense mechanism. Recently, nano-scaled v
Externí odkaz:
https://doaj.org/article/e801ebc0926a4a3c9ac04a48db219cc0
Autor:
Mahmoud Rayan, Saleh Abu Lafi, Mizied Falah, Tomas Kacergius, Agne Kirkliauskiene, Vika Gabe, Anwar Rayan
Publikováno v:
Molecules, Vol 28, Iss 4, p 1751 (2023)
Biofilms, which consist of microorganisms embedded in a polymer-rich matrix, contribute to a variety of infections and increase antimicrobial resistance. Thus, there is a constant need to develop new chemotherapeutic agents to combat biofilms. This r
Externí odkaz:
https://doaj.org/article/2a150c7c5ec1496ea809fb7a345ae0ad
Autor:
Mahmoud Rayan, Seba Shadafny, Adam Falah, Mizied Falah, Saleh Abu-Lafi, Sare Asli, Anwar Rayan
Publikováno v:
Molecules, Vol 27, Iss 3, p 961 (2022)
A novel conjugate of docetaxel and biotin (designated as IDD-1010) was designed and chemically synthesized via an ester linkage at position 2’ carbon in docetaxel. The synthesized pure IDD-1010 exhibits a potent anti-cancer activity in in vitro and
Externí odkaz:
https://doaj.org/article/f3b112756802485795d99361934a1588
Autor:
Amir Bashkin, Manar Ghanim, Basheer Abu-Farich, Mahmoud Rayan, Reem Miari, Samer Srouji, Anwar Rayan, Mizied Falah
Publikováno v:
Molecules, Vol 26, Iss 2, p 317 (2021)
Dysregulation of glucose homeostasis followed by chronic hyperglycemia is a hallmark of diabetes mellitus (DM), a disease spreading as a worldwide pandemic for which there is no satisfactory dietary treatment or cure. The development of glucose-contr
Externí odkaz:
https://doaj.org/article/0565f4591e3a4c8c8978c04bcce7ee1b
Publikováno v:
Molecules, Vol 25, Iss 16, p 3685 (2020)
Streptococcus mutans bacterium is implicated in the pathogenesis of dental caries due to the production of biofilm and organic acids from dietary sucrose. Despite the availability of various means of prophylaxis, caries still has a high worldwide pre
Externí odkaz:
https://doaj.org/article/3bb52da8a5324f76ba4ab85cc33ae2cf
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187925 (2017)
Cancer is considered one of the primary diseases that cause morbidity and mortality in millions of people worldwide and due to its prevalence, there is undoubtedly an unmet need to discover novel anticancer drugs. However, the traditional process of
Externí odkaz:
https://doaj.org/article/e1d48ad27ef649c092e800dc0b3c1726
Autor:
Vika Gabe, Tomas Kacergius, Saleh Abu-Lafi, Povilas Kalesinskas, Mahmud Masalha, Mizied Falah, Basheer Abu-Farich, Andrius Melninkaitis, Mouhammad Zeidan, Anwar Rayan
Publikováno v:
Molecules, Vol 24, Iss 3, p 529 (2019)
This study aimed to test the effectiveness of ethyl gallate (EG) against S. mutans biofilm formation on solid surfaces (polystyrene, glass) and acidogenicity, and to examine the effect on expression of related genes. The biofilm that is formed by S.
Externí odkaz:
https://doaj.org/article/e864d6579b47467b8002d6b2afebd073
Publikováno v:
Molecules, Vol 22, Iss 9, p 1563 (2017)
Diabetes mellitus (DM) poses a major health problem, for which there is an unmet need to develop novel drugs. The application of in silico techniques and optimization algorithms is instrumental to achieving this goal. A set of 97 approved anti-diabet
Externí odkaz:
https://doaj.org/article/cb6972f79e5246e38eda6a5909afb576
Autor:
Reema Fadoul, Tharwat Haj Khalil, Idan Redenski, Daniel Oren, Asaf Zigron, Avishalom Sharon, Amiel A. Dror, Mizied Falah, Samer Srouji
Publikováno v:
Stem cells and development. 31(11-12)
Endometrial polyps (EPs) are benign overgrowths of the endometrium, with the potential to cause severe complications, ranging from discomfort to inflammation and infertility. Dysfunction of endometrial fibroblasts may be a critical component leading
Autor:
Ayelet Shai, Evleen Galouk, Reem Miari, Hala Tareef, Marei Sammar, Mouhammad Zeidan, Anwar Rayan, Mizied Falah
Publikováno v:
Oncology letters. 23(4)
KRAS mutations, which are the main cause of the pathogenesis of lethal pancreatic adenocarcinomas, impair the functioning of the GTPase subunit, thus rendering it constitutively active and signaling intracellular pathways that end with cell transform